Publikationen von Matthias Mann

Sherpa, D.; Mueller, J.; Karayel, Ö.; Xu, P.; Yao, Y.; Chrustowicz, J.; Gottemukkala, K. V.; Baumann, C. A.; Gross, A.; Czarnecki, O. et al.; Zhang, W.; Gu, J.; Nilvebrant, J.; Sidhu, S. S.; Murray, P. J.; Mann, M.; Weiss, M. J.; Schulman, B. A.; Alpi, A. F.: Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation. eLife 11, e77937 (2022)

Wirth, A.-K.; Wange, L.; Vosberg, S.; Henrich, K.-O.; Rausch, C.; Oezdemir, E.; Zeller, C. M.; Richter, D.; Feuchtinger, T.; Kaller, M. et al.; Hermeking, H.; Greif, P. A.; Senft, D.; Jurinovic, V.; Bahrami, E.; Jayavelu, A. K.; Westermann, F.; Mann, M.; Enard, W.; Herold, T.; Jeremias, I.: In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance. Leukemia 36 (9), S. 2863 - 2874 (2022)

Reußwig, K.-U.; Bittmann, J.; Peritore, M.; Courtes, M.; Pardo, B.; Wierer, M.; Mann, M.; Pfander, B.: Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions. Nature Communications 13 (1), 7014 (2022)

Yahya, G.; Menges, P.; Amponsah, P. S.; Ngandiri, D. A.; Schulz, D.; Wallek, A. U.; Kulak, N. A.; Mann, M.; Cramer, P.; Savage, V. et al.; Raeschle, M.; Storchova, Z.: Sublinear scaling of the cellular proteome with ploidy. Nature Communications 13 (1), 6182 (2022)

Diamanti, K.; Cavalli, M.; Pereira, M. J.; Pan, G.; Castillejo-Lopez, C.; Kumar, C.; Mundt, F.; Komorowski, J.; Deshmukh, A. S.; Mann, M. et al.; Korsgren, O.; Eriksson, J. W.; Wadelius, C.: Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues. Cell Reports Medicine 3 (10), 100763 (2022)

Skowronek, P.; Thielert, M.; Voytik, E.; Tanzer, M. C.; Hansen, F. M.; Willems, S.; Karayel, O.; Brunner, A.-D.; Meier, F.; Mann, M.: Rapid and in-depth coverage of the (phospho-) proteome with deep libraries and optimal window design for dia-PASEF. Molecular & Cellular Proteomics 21 (9), 100279 (2022)

Meissner, F.; Geddes-McAlister, J.; Mann, M.; Bantscheff, M.: The emerging role of mass spectrometry-based proteomics in drug discovery. Nature Reviews Drug Discovery 21 (9), S. 637 - 654 (2022)

Sirinian, C.; Papanastasiou, A. D.; Karayel, O.; Degn, S. E.; Peroukidis, S.; Chaniotis, D.; Nonni, A.; Repanti, M.; Kriegsmann, M.; Makatsoris, T. et al.; Koutras, A.; Mann, M.; Kalofonos, H. P.: Analysis of RANK-c interaction partners identifies TRAF3 as a critical regulator of breast cancer aggressiveness. Neoplasia 33, 100836 (2022)

Mehta, S.; Buyanbat, A.; Kai, Y.; Karayel, O.; Goldman, S. R.; Seruggia, D.; Zhang, K.; Fujiwara, Y.; Donovan, K. A.; Zhu, Q. et al.; Yang, H.; Nabet, B.; Gray, N. S.; Mann, M.; Fischer, E. S.; Adelman, K.; Orkin, S. H.: Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degra-dation of BCL11A protein in erythroid cells. Cell Chemical Biology 29 (8), S. 1273 - 1287 (2022)

Mund, A.; Coscia, F.; Kriston, A.; Hollandi, R.; Kovacs, F.; Brunner, A. D.; Migh, E.; Schweizer, L.; Santos, A.; Bzorek, M. et al.; Naimy, S.; Rahbek-Gjerdrum, L. M.; Dyring-Andersen, B.; Bulkescher, J.; Lukas, C.; Eckert, M. A.; Lengyel, E.; Gnann, C.; Lundberg, E.; Horvath, P.; Mann, M.: Deep Visual Proteomics defines single-cell identity and heterogeneity. Nature Biotechnology 40, S. 1231 - 1240 (2022)

Schaller, T.; Maerkl, B.; Claus, R.; Sholl, L.; Hornick, J. L.; Giannetti, M. P.; Schweizer, L.; Mann, M.; Castells, M.: Mast cells in lung damage of COVID-19 autopsies: A descriptive study. Allergy: European Journal of Allergy and Clinical Immunology 77 (7), S. 2237 - 2239 (2022)

Karayel, O.; Winter, S.; Padmanabhan, S.; Kuras I, Y.; Tung Vu, D.; Tuncali, I.; Merchant, K.; Wills, A.-M.; Scherzer, C. R.; Mann, M.: Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease. Cell Reports Medicine 3 (6), 100661 (2022)

Mund, A.; Brunner, A.-D.; Mann, M.: Unbiased spatial proteomics with single-cell resolution in tissues. Molecular Cell 82 (12), S. 2335 - 2349 (2022)

Langlois, C. R.; Beier, V.; Karayel, O.; Chrustowicz, J.; Sherpa, D.; Mann, M.; Schulman, B. A.: A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters. EMBO Reports 23 (6), e53835 (2022)

Riemenschneider, H.; Guo, Q.; Bader, J. M.; Frottin, F.; Farny, D.; Kleinberger, G.; Haass, C.; Mann, M.; Hartl, F. U.; Baumeister, W. et al.; Hipp, M. S.; Meissner, F.; Fernandez-Busnadiego, R.; Edbauer, D.: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. EMBO Reports 23 (6), e53890 (2022)

Niu, L.; Thiele, M.; Geyer, P. E.; Rasmussen, D. N.; Webel, H. E.; Santos, A.; Gupta, R.; Meier, F.; Strauss, M. T.; Kjaergaard, M. et al.; Lindvig, K.; Jacobsen, S.; Rasmussen, S.; Hansen, T.; Krag, A.; Mann, M.: Noninvasive proteomic biomarkers for alcohol-related liver disease. Nature Medicine 28 (6), S. 1277 - 1287 (2022)

Qiao, S.; Lee, C.-W.; Sherpa, D.; Chrustowicz, J.; Cheng, J. D.; Duennebacke, M.; Steigenberger, B.; Karayel, O.; Tung Vu, D.; Gronau, S. v. et al.; Mann, M.; Wilfling, F.; Schulman, B.: Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nature Communications 13 (1), 3041 (2022)

Bludau, I.; Willems, S.; Zeng, W.-F.; Strauss, M. T.; Hansen, F. M.; Tanzer, M. C.; Karayel, O.; Schulman, B. A.; Mann, M.: The structural context of posttranslational modifications at a proteome-wide scale. PLoS Biology 20 (5), e3001636 (2022)

Fan, Y. X.; Murgia, M.; Linder, M. I.; Mizoguchi, Y.; Wang, C.; Lyszkiewicz, M.; Zietara, N.; Liu, Y. S.; Frenz, S.; Sciuccati, G. et al.; Partida-Gaytan, A.; Alizadeh, Z.; Rezaei, N.; Rehling, P.; Dennerlein, S.; Mann, M.; Klein, C.: HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation. The Journal of Clinical Investigation 132 (9), e153153 (2022)

Niu, L.; Geyer, P. E.; Gupta, R.; Santos, A.; Meier, F.; Doll, S.; Albrechtsen, N. J. W.; Klein, S.; Ortiz, C.; Uschner, F. E. et al.; Schierwagen, R.; Trebicka, J.; Mann, M.: Dynamic human liver proteome atlas reveals functional insights into disease pathways. Molecular Systems Biology 18 (5), e10947 (2022)