Publikationen des Instituts

Zheng, X.; Mund, A.; Mann, M.: Protocol for spatial proteomic profiling of tonsil cancer microenvironments using multiplexed imaging-powered deep visual proteomics. STAR Protocols 6 (3), 103901 (2025)

Hansen, K. G.; Baxter-Koenigs, A.; Weiss, C. A. M.; Mcshane, E.; Churchman, L. S.: Transcription arrest induces formation of RNA granules in mitochondria. Life science alliance 8 (9), e202403082 (2025)

Fotovati, M.; Lee, J. W.; Taheri, M.; Ghassempour, A.; Rezadoost, H.; Seidel-Morgenstern, A.: Chromatographic method to isolate valuable ingredients of saffron extracts. Journal of Chromatography A 1757, 466098 (2025)

Riggi, M.; Iwasa, J. H.: Agent-based modeling of complex molecular mechanisms. Seminars in Cell & Developmental Biology 172, 103626 (2025)

Itang, E. C. M.; Albrecht, V.; Schebesta, A.-S.; Thielert, M.; Lanz, A.-L.; Danhauser, K.; Jin, J.; Prell, T.; Strobel, S.; Klein, C. et al.; Mann, M.; Pangratz-Fuehrer, S.; Mueller-Reif, J. B.: Ontology-guided clustering enables proteomic analysis of rare pediatric disorders. Embo Molecular Medicine 17 (7), S. 1842 - 1867 (2025)

Pesch, G.; Piseddu, I.; Gaertig, J.; Kramer, N.; Kramer, R.; Schulz, T. U.; Zwiebel, M.; Ledderose, S.; Retzlaff, J.; Eckstein, M. et al.; Schett, G.; Kammerbauer, C.; Schmitt, C.; Kumbrink, J.; Erdmann, M.; Kruis, W.; Dougan, M.; Mayerle, J.; French, L. E.; Vera, J.; Nordmann, T. M.; Mann, M.; Klauschen, F.; Anz, D.; Heinzerling, L.: Deep immune phenotyping reveals distinct immunopathogenesis in checkpoint inhibitor-induced colitis compared to ulcerative colitis. Cancer Immunology Research 13 (7), S. 1053 - 1069 (2025)

Huber, L.; Kucera, T.; Hoellerer, S.; Borgwardt, K.; Panke, S.; Jeschek, M.: Data-driven Protease Engineering by DNA-Recording and Epistasis-aware Machine Learning. Nature Communications 16, 5466 (2025)

Ogger, P. P.: Loss of Iron Regulatory Protein 2 (IRP2) Protects Mice from Lung Inflammation during Bronchoconstriction. American Journal of Respiratory Cell and Molecular Biology 73 (1), S. 12 - 13 (2025)

Pesch, G.; Piseddu, I.; Gaertig, J.; Kramer, N.; Kramer, R.; Schulz, T. U.; Zwiebel, M.; Ledderose, S.; Retzlaff, J.; Eckstein, M. et al.; Schett, G.; Kammerbauer, C.; Schmitt, C.; Kumbrink, J.; Erdmann, M.; Kruis, W.; Dougan, M.; Mayerle, J.; French, L. E.; Vera, J.; Nordmann, T. M.; Mann, M.; Klauschen, F.; Anz, D.; Heinzerling, L.: Deep Immune Phenotyping Reveals Distinct Immunopathogenesis in Checkpoint Inhibitor-Induced Colitis Compared with Ulcerative Colitis. CANCER IMMUNOLOGY RESEARCH 13 (7), S. 1053 - 1069 (2025)

Shang, X.; Bartels, N.; Weck, J. M.; Suppmann, S.; Basquin, J.; Thaventhiran, G.; Heuer-Jungemann, A.; Monzel, C.: High yield purification of an isoleucine zipper-modified CD95 ligand for efficient cell apoptosis initiation and with biotin or DNA-oligomer binding domain to probe ligand functionalization effects. BMC Biotechnology 25 (1), 64 (2025)

Honsa, M.; Pachmayr, I.; Heinze, L.; Bas, L.; Masullo, L. A.; Kwon, J.; Perovic, A.; Schulman, B. A.; Jungmann, R.: Imaging Ligand-Receptor Interactions at Single-Protein Resolution with DNA-PAINT. Small Methods 9 (6), 2401799 (2025)

Weck, J. M.; Nair, R.; Kesici, M.-Z.; Shang, X.; Gavrilovic, S.; Monzel, C.; Heuer-Jungemann, A.: Effects of DNA Origami-Based Nanoagent Design on Apoptosis Induction in a Large 3D Cancer Spheroid Model. Small 21 (24), 2502490 (2025)

Kraehenbuehl, L.; Winkelbeiner, N.; Turko, P.; Staeger, R.; Ghosh, A.; Kaiser, V.; Stadler, P.-C.; Nordmann, T. M.; Brüggen, M.-C.; Levesque, M. P. et al.; Contassot, E.; French, L. E.; Dummer, R.; Meier-Schiesser, B.: Immune-Related Cutaneous Adverse Events Display Distinct Clinical and Molecular Characteristics, Depending on Immune Checkpoints Targeted. Cancers 17 (12), 1992 (2025)

Klebl, D. P.; McMillan, S. N.; Risi, C.; Forgacs, E.; Virok, B.; Atherton, J. L.; Harris, S. A.; Stofella, M.; Winkelmann, D. A.; Sobott, F. et al.; Galkin, V. E.; Knight, P. J.; Muench, S. P.; Scarff, C. A.; White, H. D.: Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM. Nature 642 (8067), S. 519 - 526 (2025)

Rosenberger, F. A.; Mädler, S. C.; Thorhauge, K. H.; Steigerwald, S.; Fromme, M.; Lebedev, M.; Weiss, C. A. M.; Oeller, M.; Wahle, M.; Metousis, A. et al.; Zwiebel, M.; Schmacke, N. A.; Detlefsen, S.; Boor, P.; Fabian, O.; Frankova, S.; Krag, A.; Strnad, P.; Mann, M.: Deep Visual Proteomics maps proteotoxicity in a genetic liver disease. Nature 642 (8067), S. 484 - 491 (2025)

Paloja, K.; Rodriguez-Franco, H. J.; Jungmann, R.; Parish, I. A.; Bastings, M. M. C.: Multivalent Presentation of TCRs on DNA Nanostructures as a Sensitive Probe for pMHC Detection. ACS Applied Nano Materials 8 (24), S. 12490 - 12497 (2025)

Velazco, A.; Glen, T.; Klumpe, S.; Pennington, A.; Zhang, J.; Smith, J. L. R.; Glynn, C.; Bowles, W.; Kobylynska, M.; Fleck, R. A. et al.; Naismith, J. H.; Kim, J. S.; Darrow, M. C.; Grange, M.; Kirkland, A. I.; Dumoux, M.: Reduction of SEM charging artefacts in native cryogenic biological samples. Nature Communications 16, 5204 (2025)

Bone, R. A.; Lowndes, M. P.; Raineri, S.; Riveiro, A.; Lundregan, S. L.; Dall, M.; Sulek, K.; Romero, J. A. H.; Malzard, L.; Koigi, S. et al.; Heckenbach, I. J.; Solis-Mezarino, V.; Voelker-Albert, M.; Vasilopoulou, C.; Meier, F.; Trusina, A.; Mann, M.; Nielsen, M.; Treebak, J. T.; Brickman, J. M.: Altering metabolism programs cell identity via NAD+-dependent deacetylation. The EMBO Journal 44 (11), S. 3056 - 3084 (2025)

Coscia, F.; Nielsen, A. B.; Weigert, M.; Watters, K.; Javellana, M.; Anglesio, M.; Yamada, S. D.; Lastra, R. R.; Mann, M.; Lengyel, E.: A Proteogenomic View of Synchronous Endometrioid Endometrial and Ovarian Cancer. Clinical Cancer Research 31 (11), S. 2230 - 2240 (2025)

Nachmias, D.; Frohn, B. P.; Sachse, C.; Mizrahi, I.; Elia, N.: ESCRTs - A multi-purpose membrane remodeling device encoded in all life forms. Trends in Microbiology 33 (6), S. 665 - 687 (2025)