Publikationen von M. Kaiser

Tennstaedt, A.; Popsel, S.; Truebestein, L.; Hauske, P.; Brockmann, A.; Schmidt, N.; Irle, I.; Sacca, B.; Niemeyer, C. M.; Brandt, R. et al.; Ksiezak-Reding, H.; Tirniceriu, A. L.; Egensperger, R.; Baldi, A.; Dehmelt, L.; Kaiser, M.; Huber, R.; Clausen, T.; Ehrmann, M.: Human High Temperature Requirement Serine Protease A1 (HTRA1) Degrades Tau Protein Aggregates. Journal of Biological Chemistry 287 (25), S. 20931 - 20941 (2012)

Weski, J.; Meltzer, M.; Spaan, L.; Monig, T.; Oeljeklaus, J.; Hauske, P.; Vouilleme, L.; Volkmer, R.; Boisguerin, P.; Boyd, D. et al.; Huber, R.; Kaiser, M.; Ehrmann, M.: Chemical Biology Approaches Reveal Conserved Features of a C-Terminal Processing PDZ Protease. ChemBioChem 13 (3), S. 402 - 408 (2012)

Clausen, T.; Kaiser, M.; Huber, R.; Ehrmann, M.: HTRA proteases: regulated proteolysis in protein quality control. Nature Reviews Molecular Cell Biology 12 (3), S. 152 - 162 (2011)

Merdanovic, M.; Clausen, T.; Kaiser, M.; Huber, R.; Ehrmann, M.: Protein Quality Control in the Bacterial Periplasm. Annual Review of Microbiology 65, S. 149 - 168 (2011)

Clerc, J.; Schellenberg, B.; Groll, M.; Bachmann, A. S.; Huber, R.; Dudler, R.; Kaiser, M.: Convergent Synthesis and Biological Evaluation of Syringolin A and Derivatives as Eukaryotic 20S Proteasome Inhibitors. European Journal of Organic Chemistry (21), S. 3991 - 4003 (2010)

Merdanovic, M.; Mamant, N.; Meltzer, M.; Poepsel, S.; Auckenthaler, A.; Melgaard, R.; Hauske, P.; Nagel-Steger, L.; Clarke, A. R.; Kaiser, M. et al.; Huber, R.; Ehrmann, M.: Determinants of structural and functional plasticity of a widely conserved protease chaperone complex. Nature Structural & Molecular Biology 17 (7), S. 837 - 843 (2010)

Hasenbein, S.; Meltzer, M.; Hauske, P.; Kaiser, M.; Huber, R.; Clausen, T.; Ehrmann, M.: Conversion of a Regulatory into a Degradative Protease. Journal of Molecular Biology 397 (4), S. 957 - 966 (2010)

Wetzel, S.; Wilk, W.; Chammaa, S.; Sperl, B.; Roth, A. G.; Yektaoglu, A.; Renner, S.; Berg, T.; Arenz, C.; Giannis, A. et al.; Oprea, T. I.; Rauh, D.; Kaiser, M.; Waldmann, H.: A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of gamma-Pyrones. Angewandte Chemie-International Edition 49 (21), S. 3666 - 3670 (2010)

Clerc, J.; Florea, B. I.; Kraus, M.; Groll, M.; Huber, R.; Bachmann, A. S.; Dudler, R.; Driessen, C.; Overkleeft, H. S.; Kaiser, M.: Syringolin A Selectively Labels the 20 S Proteasome in Murine EL4 and Wild-Type and Bortezomib-Adapted Leukaemic Cell Lines. ChemBioChem 10 (16), S. 2638 - 2643 (2009)

Meltzer, M.; Hasenbein, S.; Mamant, N.; Merdanovic, M.; Poepsel, S.; Hauske, P.; Kaiser, M.; Huber, R.; Krojer, T.; Clausen, T. et al.; Ehrmann, M.: Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli. Research in Microbiology 160 (9 Sp. Iss.), S. 660 - 666 (2009)

Ottmann, C.; Rose, R.; Huttenlocher, F.; Cedzich, A.; Hauske, P.; Kaiser, M.; Huber, R.; Schaller, A.: Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3. Proceedings of the National Academy of Sciences of the United States of America 106 (40), S. 17223 - 17228 (2009)

Clerc, J.; Groll, M.; Illich, D. J.; Bachmann, A. S.; Huber, R.; Schellenberg, B.; Dudler, R.; Kaiser, M.: Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition. Proceedings of the National Academy of Sciences of the United States of America 106 (16), S. 6507 - 6512 (2009)

Groll, M.; Schellenberg, B.; Bachmann, A. S.; Archer, C. R.; Huber, R.; Powell, T. K.; Lindow, S.; Kaiser, M.; Dudler, R.: A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism. NATURE 452 (7188), S. 755 - 758 (2008)

Gotz, M. G.; Groll, M.; Kaiser, M.; Weyher, E.; Moroder, L.: MEDI 24-Macrocyclic peptidyl biaryl-ether inhibitors provide evidence for the catalytic versatility of the 20S proteasome. Abstracts of Papers of the American Chemical Society 235, S. 24-MEDI (2008)

Groll, M.; Götz, M.; Kaiser, M.; Weyher, E.; Moroder, L.: TMC-95-based inhibitor design provides evidence for the catalytic versatility of the proteasome. Chemistry & Biology 13 (6), S. 607 - 614 (2006)

Musiol, H. J.; Dong, S. L.; Kaiser, M.; Bausinger, R.; Zurnbusch, A.; Bertsch, U.; Moroder, L.: Toward semisynthetic lipoproteins by convergent strategies based on click and ligation chemistry. ChemBioChem 6 (4), S. 625 - 628 (2005)

Kaiser, M.; Groll, M.; Siciliano, C.; Assfalg-Machleidt, I.; Weyher, E.; Kohno, J.; Milbradt, A. G.; Renner, C.; Huber, R.; Moroder, L.: Binding mode of TMC-95A analogues to eukaryotic 20S proteasome. ChemBioChem 5 (9), S. 1256 - 1266 (2004)

Kaiser, M.; Milbradt, A. G.; Siciliano, C.; Assfalg-Machleidt, I.; Machleidt, W.; Groll, M.; Renner, C.; Moroder, L.: TMC-95A analogues with endocyclic biphenyl ether group as proteasome inhibitors. Chemistry & Biodiversity 1 (1), S. 161 - 173 (2004)

Kaiser, M.; Siciliano, C.; Assfalg-Machleidt, I.; Groll, M.; Milbradt, A. G.; Moroder, L.: Synthesis of a TMC-95A ketomethylene analogue by cyclization via intramolecular Suzuki coupling. Organic Letters 5 (19), S. 3435 - 3437 (2003)

Kaiser, M.; Milbradt, A. G.; Moroder, L.: Synthesis of TMC-95A analogues. Structure-based prediction of cyclization propensities of linear precursors. Letters in Peptide Science 9 (2-3), S. 65 - 70 (2003)