Publikationen von Reinhard Fässler

Bharadwaj, M.; Strohmeyer, N.; Colo, G. P.; Helenius, J.; Beerenwinkel, N.; Schiller, H. B.; Fässler, R.; Müller, D. J.: αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin. Nature Communications 8, 14348 (2017)

Böttcher, R. T.; Sun, Z.; Fässler, R.: A forceful connection: mechanoregulation of oncogenic YAP. The EMBO Journal 36 (17), S. 2467 - 2469 (2017)

Böttcher, R. T.; Veelders, M.; Rombaut, P.; Faix, J.; Theodosiou, M.; Stradal, T. E.; Rottner, K.; Zent, R.; Herzog, F.; Fässler, R.: Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. Journal of Cell Biology 216 (11), S. 3785 - 3798 (2017)

Kammerer, P.; Aretz, J.; Fässler, R.: Lucky kindlin: A cloverleaf at the integrin tail. Proceedings of the National Academy of Sciences of the United States of America 114 (35), S. 9234 - 9236 (2017)

Mathew, S.; Palamuttam, R. J.; Mernaugh, G.; Ramalingam, H.; Lu, Z.; Zhang, M.-Z.; Ishibe, S.; Critchley, D. R.; Fässler, R.; Pozzi, A. et al.; Sanders, C. R.; Carroll, T. J.; Zent, R.: Talin regulates integrin beta 1-dependent and -independent cell functions in ureteric bud development. Development 144 (22), S. 4148 - 4158 (2017)

Lu, Z.; Mathew, S.; Chen, J.; Hadziselimovic, A.; Palamuttam, R.; Hudson, B. G.; Fässler, R.; Pozzi, A.; Sanders, C. R.; Zent, R.: Implications of the differing roles of the beta 1 and beta 3 transmembrane and cytosplasmic domains for integrin function. eLife 5, e18633 (2016)

Cerikan, B.; Shaheen, R.; Colo, G. P.; Glaesser, C.; Hata, S.; Knobeloch, K.-P.; Alkuraya, F. S.; Faessler, R.; Schiebel, E.: Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator. Developmental Cell 39 (1), S. 28 - 43 (2016)

Rognoni, E.; Ruppert, R.; Fässler, R.: The kindlin family: functions, signaling properties and implications for human disease. Journal of Cell Science 129 (1), S. 17 - 27 (2016)

Cheah, M.; Andrews, M. R.; Chew, D. J.; Moloney, E. B.; Verhaagen, J.; Fässler, R.; Fawcett, J. W.: Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord. The Journal of Neuroscience 36 (27), S. 7283 - 7297 (2016)

Geiger, B.; Fässler, R.: Introduction to the ECR special issue, "Mechanosensing via Cell-Matrix Adhesions". EXPERIMENTAL CELL RESEARCH 343 (1), S. 1 - 2 (2016)

Hermann, M.-R.; Jakobson, M.; Colo, G. P.; Rognoni, E.; Jakobson, M.; Kupatt, C.; Posern, G.; Fässler, R.: Integrins synergise to induce expression of the MRTF-A-SRF target gene ISG15 for promoting cancer cell invasion. JOURNAL OF CELL SCIENCE 129 (7), S. 1391 - 1403 (2016)

Lukjanenko, L.; Jung, M. J.; Hegde, N.; Perruisseau-Carrier, C.; Migliavacca, E.; Rozo, M.; Karaz, S.; Jacot, G.; Schmidt, M.; Li, L. et al.; Metairon, S.; Raymond, F.; Lee, U.; Sizzano, F.; Wilson, D. H.; Dumont, N. A.; Palini, A.; Fässler, R.; Steiner, P.; Descombes, P.; Rudnicki, M. A.; Fan, C.-M.; von Maltzahn, J.; Feige, J. N.; Bentzinger, C. F.: Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice. Nature Medicine 22 (8), S. 897 - 905 (2016)

Sun, Z.; Guo, S. S.; Fässler, R.: Integrin-mediated mechanotransduction. The Journal of Cell Biology: JCB 215 (4), S. 445 - 456 (2016)

Sun, Z.; Tseng, H.-Y.; Tan, S.; Senger, F.; Kurzawa, L.; Dedden, D.; Mizuno, N.; Wasik, A. A.; Thery, M.; Dunn, A. R. et al.; Fässler, R.: Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation. Nature Cell Biology 18 (9), S. 941 - 953 (2016)

Theodosiou, M.; Widmaier, M.; Böttcher, R. T.; Rognoni, E.; Veelders, M.; Bharadwaj, M.; Lambacher, A.; Austen, K.; Müller, D. J.; Zent, R. et al.; Fässler, R.: Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. ELIFE 5, e10130 (2016)

Giancotti, F. G.; Fässler, R.: Guido Tarone, Ph.D. (1951-2015) OBITUARY. JOURNAL OF CELL SCIENCE 128 (16), S. 2955 - 2956 (2015)

Karaköse, E.; Geiger, T.; Flynn, K.; Lorenz-Baath, K.; Zent, R.; Mann, M.; Fässler, R.: The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites. Journal of Cell Science 128 (5), S. 1023 - 1033 (2015)

Klapproth, S.; Moretti, F. A.; Zeiler, M.; Ruppert, R.; Breithaupt, U.; Mueller, S.; Haas, R.; Mann, M.; Sperandio, M.; Fässler, R. et al.; Moser, M.: Minimal amounts of kindlin-3 suffice for basal platelet and leukocyte functions in mice. BLOOD 126 (24), S. 2592 - 2600 (2015)

Klapproth, S.; Sperandio, M.; Pinheiro, E. M.; Pruenster, M.; Soehnlein, O.; Gertler, F. B.; Fässler, R.; Moser, M.: Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired beta 2 integrin function in mice. BLOOD 126 (25), S. 2704 - 2712 (2015)

Ruppert, R.; Moser, M.; Sperandio, M.; Rognoni, E.; Orban, M.; Liu, W.-H.; Schulz, A. S.; Oostendorp, R. A. J.; Massberg, S.; Fässler, R.: Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells. JOURNAL OF EXPERIMENTAL MEDICINE 212 (9), S. 1415 - 1432 (2015)