Suchergebnisse

Fischer, L.; Klingner, C.; Schlichthärle, T.; Strauss, M. T.; Böttcher, R. T.; Fässler, R.; Jungmann, R.; Grashoff, C.: Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion. Nature Communications 12 (1), 919 (2021)

Orre, T.; Joly, A.; Karatas, Z.; Kastberger, B.; Cabriel, C.; Böttcher, R. T.; Leveque-Fort, S.; Sibarita, J.-B.; Fässler, R.; Wehrle-Haller, B. et al.; Rossier, O.; Giannone, G.: Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions. Nature Communications 12 (1), 3104 (2021)

Samarelli, A. V.; Ziegler, T.; Meves, A.; Fässler, R.; Böttcher, R. T.: Rabgap1 promotes recycling of active beta1 integrins to support effective cell migration. Journal of Cell Science 133 (18), jcs243683 (2020)

Shirakawa, J.; Kajikawa, S.; Böttcher, R. T.; Costell, M.; Izu, Y.; Hayata, T.; Noda, M.; Ezura, a. Y.: Profilin 1 Negatively Regulates Osteoclast Migration in Postnatal Skeletal Growth, Remodeling, and Homeostasis in Mice. JBMR Plus 3 (6), e10130 (2019)

Tseng, H.-Y.; Samarelli, A. V.; Kammerer, P.; Scholze, S.; Ziegler, T.; Immler, R.; Zent, R.; Sperandio, M.; Sanders, C. R.; Fässler, R. et al.; Böttcher, R. T.: LCP1 preferentially binds clasped alpha M beta 2 integrin and attenuates leukocyte adhesion under flow. Journal of Cell Science 131 (22), UNSP jcs218214 (2018)

Heim, J. B.; McDonald, C. A.; Wyles, S. P.; Sominidi-Damodaran, S.; Squirewel, E. J.; Li, M.; Motsonelidze, C.; Böttcher, R. T.; van Deursen, J.; Meves, A.: FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis. PLoS One 13 (7), e0200558 (2018)

Lin, W.; Izu, Y.; Smriti, A.; Kawasaki, M.; Pawaputanon, C.; Böttcher, R. T.; Costell, M.; Moriyama, K.; Noda, M.; Ezura, Y.: Profilin1 is expressed in osteocytes and regulates cell shape and migration. Journal of Cellular Physiology 233 (1), S. 259 - 268 (2018)

Wujak, L.; Böttcher, R. T.; Pak, O.; Frey, H.; El Agha, E.; Chen, Y.; Schmitt, S.; Bellusci, S.; Schaefer, L.; Weissmann, N. et al.; Fässler, R.; Wygrecka, M.: Low density lipoprotein receptor-related protein 1 couples beta 1 integrin activation to degradation. Cellular and Molecular Life Sciences 75 (9), S. 1671 - 1685 (2018)

Gaertner, F.; Ahmad, Z.; Rosenberger, G.; Fan, S.; Nicolai, L.; Busch, B.; Yavuz, G.; Luckner, M.; Ishikawa-Ankerhold, H.; Hennel, R. et al.; Benechet, A.; Lorenz, M.; Chandraratne, S.; Schubert, I.; Helmer, S.; Striednig, B.; Stark, K.; Janko, M.; Böttcher, R. T.; Verschoor, A.; Leon, C.; Gachet, C.; Gudermann, T.; Mederos y Schnitzler, M.; Pincus, Z.; Iannacone, M.; Haas, R.; Wanner, G.; Lauber, K.; Sixt, M.; Massberg, S.: Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria. Cell 171 (6), S. 1368 - 1382.e23 (2017)

Böttcher, R. T.; Sun, Z.; Fässler, R.: A forceful connection: mechanoregulation of oncogenic YAP. The EMBO Journal 36 (17), S. 2467 - 2469 (2017)

Böttcher, R. T.; Veelders, M.; Rombaut, P.; Faix, J.; Theodosiou, M.; Stradal, T. E.; Rottner, K.; Zent, R.; Herzog, F.; Fässler, R.: Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. Journal of Cell Biology 216 (11), S. 3785 - 3798 (2017)

Gau, D.; Veon, W.; Capasso, T. L.; Bottcher, R.; Shroff, S.; Roman, B. L.; Roy, P.: Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis. Angiogenesis 20 (4), S. 663 - 672 (2017)

Heim, J. B.; Squirewell, E. J.; Neu, A.; Zocher, G.; Sominidi-Damodaran, S.; Wyles, S. P.; Nikolova, E.; Behrendt, N.; Saunte, D. M.; Lock-Andersen, J. et al.; Gaonkar, K. S.; Yan, H.; Sarkaria, J. N.; Krendel, M.; van Deursen, J.; Sprangers, R.; Stehle, T.; Böttcher, R. T.; Lee, J.-H.; Ordog, T.; Meves, A.: Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proceedings of the National Academy of Sciences of the United States of America 114 (15), S. 3933 - 3938 (2017)

Jiang, C.; Ding, Z.; Joy, M.; Chakraborty, S.; Kim, S. H.; Bottcher, R.; Condeelis, J.; Singh, S.; Roy, P.: A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells. Cell Cycle 16 (24), S. 2366 - 2373 (2017)

Pick, R.; Begandt, D.; Stocker, T. J.; Salvermoser, M.; Thome, S.; Böttcher, R. T.; Montanez, E.; Harrison, U.; Forne, I.; Khandoga, A. G. et al.; Coletti, R.; Weckbach, L. T.; Brechtefeld, D.; Haas, R.; Imhof, A.; Massberg, S.; Sperandio, M.; Walzog, B.: Coronin 1A, a novel player in integrin biology, controls neutrophil trafficking in innate immunity. Blood 130 (7), S. 847 - 858 (2017)

Mana, G.; Clapero, F.; Panieri, E.; Panero, V.; Böttcher, R. T.; Tseng, H.-Y.; Saltarin, F.; Astanina, E.; Wolanska, K. I.; Morgan, M. R. et al.; Humphries, M. J.; Santoro, M. M.; Serini, G.; Valdembri, D.: PPFIA1 drives active alpha 5 beta 1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nature Communications 7, 13546 (2016)

Deuschle, E.; Keller, B.; Siegfried, A.; Manncke, B.; Spaeth, T.; Köberle, M.; Drechsler-Hake, D.; Reber, J.; Böttcher, R. T.; Autenrieth, S. E. et al.; Autenrieth, I. B.; Bohn, E.; Schütz, M.: Role of beta 1 integrins and bacterial adhesins for Yop injection into leukocytes in Yersinia enterocolitica systemic mouse infection. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY 306 (2), S. 77 - 88 (2016)

Theodosiou, M.; Widmaier, M.; Böttcher, R. T.; Rognoni, E.; Veelders, M.; Bharadwaj, M.; Lambacher, A.; Austen, K.; Müller, D. J.; Zent, R. et al.; Fässler, R.: Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. ELIFE 5, e10130 (2016)

Yazlovitskaya, E. M.; Tseng, H.-Y.; Viquez, O.; Tu, T.; Mernaugh, G.; McKee, K. K.; Riggins, K.; Quaranta, V.; Pathak, A.; Carter, B. D. et al.; Yurchenco, P.; Sonnenberg, A.; Böttcher, R. T.; Pozzi, A.; Zent, R.: Integrin alpha 3 beta 1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. MOLECULAR BIOLOGY OF THE CELL 26 (10), S. 1857 - 1874 (2015)

Rognoni, E.; Widmaier, M.; Jakobson, M.; Ruppert, R.; Ussar, S.; Katsougkri, D.; Böttcher, R. T.; Lai-Cheong, J. E.; Rifkin, D. B.; McGrath, J. A. et al.; Fässler, R.: Kindlin-1 controls Wnt and TGF-beta availability to regulate cutaneous stem cell proliferation. Nature Medicine 20 (4), S. 350 - 359 (2014)