Publikationen von Reinhard Fässler

Brod, F.; Fässler, R.: A FAK conundrum is solved: activation and organization of focal adhesion kinase at the plasma membrane. EMBO Journal 39, e106234 (2020)

Benito-Jardon, M.; Strohmeyer, N.; Ortega-Sanchis, S.; Bharadwaj, M.; Moser, M.; Mueller, D. J.; Fässler, R.; Costell, M.: alpha v-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation. The Journal of Cell Biology 219 (12), e202004198 (2020)

Guo, S. S.; Au, T. Y. K.; Wynn, S.; Aszodi, A.; Chan, D.; Fässler, R.; Cheah, K. S. E.: beta 1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs. Development 147 (22), dev192724 (2020)

Krenn, P. W.; Koschmieder, S.; Fässler, R.: Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches. Proceedings of the National Academy of Sciences of the United States of America 117 (39), S. 24326 - 24335 (2020)

Mole, M. A.; Galea, G. L.; Rolo, A.; Weberling, A.; Nychyk, O.; De Castro, S. C.; Savery, D.; Fässler, R.; Ybot-Gonzalez, P.; Greene, N. D. E. et al.; Copp, A. J.: Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure. DEVELOPMENTAL CELL 52 (3), S. 321 - 334 (2020)

Pinto-Costa, R.; Sousa, S. C.; Leite, S. C.; Nogueira-Rodrigues, J.; da Silva, T. F.; Machado, D.; Marques, J.; Costa, A. C.; Liz, M. A.; Bartolini, F. et al.; Brites, P.; Costell, M.; Fässler, R.; Sousa, M. M.: Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration. JOURNAL OF CLINICAL INVESTIGATION 130 (4), S. 2024 - 2040 (2020)

Reich, D.; Kresinsky, A.; Müller, J. P.; Bauer, R.; Kallenbach, J.; Schnoeder, T. M.; Heidel, F. H.; Fässler, R.; Mann, M.; Böhmer, F.-D. et al.; Jayavelu, A. K.: SHP1 regulates a STAT6-ITGB3 axis in FLT3ITD-positive AML cells. LEUKEMIA 34 (5), S. 1444 - 1449 (2020)

Samarelli, A. V.; Ziegler, T.; Meves, A.; Fässler, R.; Böttcher, R. T.: Rabgap1 promotes recycling of active beta1 integrins to support effective cell migration. Journal of Cell Science 133 (18), jcs243683 (2020)

Spoerri, P. M.; Strohmeyer, N.; Sun, Z.; Fässler, R.; Müller, D. J.: Protease-activated receptor signalling initiates alpha(5)beta(1)-integrin-mediated adhesion in non-haematopoietic cells. NATURE MATERIALS 19, S. 218 - 226 (2020)

Dedden, D.; Schumacher, S.; Kelley, C.; Zacharias, M.; Biertümpfel, C.; Fässler, R.; Mizuno, N.: The Architecture of Talin1 Reveals an Autoinhibition Mechanism. CELL 179 (1), S. 120 - 131.e13 (2019)

Hubeau, C.; Gerard, C.; Carnet, O.; Moser, M.; Fässler, R.; Noel, A.; Rocks, N.; Cataldo, D.: Microenvironment-Derived ADAM28 Impacts the Onset of Lung Cancer. JOURNAL OF THORACIC ONCOLOGY 14 (10, Suppl.), P1.04-65, S. S466 - S466 (2019)

Sun, Z.; Costell, M.; Fässler, R.: Integrin activation by talin, kindlin and mechanical forces. Nature Cell Biology 21 (1), S. 25 - 31 (2019)

Volckaert, T.; Yuan, T.; Yuan, J.; Boateng, E.; Hopkins, S.; Zhang, J.-S.; Thannickal, V. J.; Fässler, R.; De Langhe, S. P.: Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and beta-catenin signaling. Development 146 (2), UNSP dev166454 (2019)

Tseng, H.-Y.; Samarelli, A. V.; Kammerer, P.; Scholze, S.; Ziegler, T.; Immler, R.; Zent, R.; Sperandio, M.; Sanders, C. R.; Fässler, R. et al.; Böttcher, R. T.: LCP1 preferentially binds clasped alpha M beta 2 integrin and attenuates leukocyte adhesion under flow. Journal of Cell Science 131 (22), UNSP jcs218214 (2018)

Chen, N.-P.; Sun, Z.; Fässler, R.: The Kank family proteins in adhesion dynamics. Current Opinion in Cell Biology 54, S. 130 - 136 (2018)

Gerard, C.; Hubeau, C.; Carnet, O.; Bellefroid, M.; Sounni, N. E.; Blacher, S.; Bendavid, G.; Moser, M.; Fässler, R.; Noel, A. et al.; Cataldo, D.; Rocks, N.: Microenvironment-derived ADAM28 prevents cancer dissemination. Oncotarget 9 (98), S. 37185 - 37199 (2018)

Moretti, F. A.; Klapproth, S.; Ruppert, R.; Margraf, A.; Jasmin, W.; Pick, R.; Scheiermann, C.; Sperandio, M.; Fässler, R.; Moser, M.: Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. eLife 7, e35816 (2018)

Wujak, L.; Böttcher, R. T.; Pak, O.; Frey, H.; El Agha, E.; Chen, Y.; Schmitt, S.; Bellusci, S.; Schaefer, L.; Weissmann, N. et al.; Fässler, R.; Wygrecka, M.: Low density lipoprotein receptor-related protein 1 couples beta 1 integrin activation to degradation. Cellular and Molecular Life Sciences 75 (9), S. 1671 - 1685 (2018)

Ringer, P.; Colo, G.; Fässler, R.; Grashoff, C.: Sensing the mechano-chemical properties of the extracellular matrix. Matrix Biology 64, S. 6 - 16 (2017)

Strohmeyer, N.; Bharadwaj, M.; Costell, M.; Fässler, R.; Müller, D. J.: Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second. Nature Materials 16, S. 1262 - 1270 (2017)