Publikationen von R. Huber

Garrido-Franco, M.; Ehlert, S.; Messerschmidt, A.; Marinkovic, S.; Huber, R.; Laber, B.; Bourenkov, G. P.; Clausen, T.: Structure and function of threonine synthase from yeast. Journal of Biological Chemistry 277 (14), S. 12396 - 12405 (2002)

Krojer, T.; Garrido-Franco, M.; Huber, R.; Ehrmann, M.; Clausen, T.: Crystal structure of DegP (HtrA) reveals a new protease- chaperone machine. Nature 416 (6879), S. 455 - 459 (2002)

Friedrich, R.; Steinmetzer, T.; Huber, R.; Stürzebecher, J.; Bode, W.: The methyl group of N-alpha(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage. Journal of Molecular Biology 316 (4), S. 869 - 874 (2002)

Richardson, J. L.; Fuentes-Prior, P.; Sadler, J. E.; Huber, R.; Bode, W.: Characterization of the residues involved in the human alpha- thrombin-haemadin complex: An exosite II-binding inhibitor. Biochemistry 41 (8), S. 2535 - 2542 (2002)

Schramek, N.; Bracher, A.; Fischer, M.; Auerbach, G.; Nar, H.; Huber, R.; Bacher, A.: Reaction mechanism of GTP cyclohydrolase I: Single turnover experiments using a kinetically competent reaction intermediate. Journal of Molecular Biology 316 (3), S. 829 - 837 (2002)

Grazulis, S.; Deibert, M.; Rimseliene, R.; Skirgaila, R.; Sasnauskas, G.; Lagunavicius, A.; Repin, V.; Urbanke, C.; Huber, R.; Siksnys, V.: Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence. Nucleic Acids Research 30 (4), S. 876 - 885 (2002)

Friedrich, R.; Fuentes-Prior, P.; Ong, E.; Coombs, G.; Hunter, M.; Oehler, R.; Pierson, D.; Gonzalez, R.; Huber, R.; Bode, W. et al.; Madison, E. L.: Catalytic domain structures of MT-SP1/matriptase, a matrix- degrading transmembrane serine proteinase. Journal of Biological Chemistry 277 (3), S. 2160 - 2168 (2002)

Budisa, N.; Rubini, M.; Bae, J. H.; Weyher, E.; Wenger, W.; Golbik, R.; Huber, R.; Moroder, L.: Global replacement of tryptophan with aminotryptophans generates non-invasive protein-based optical pH sensors. Angewandte Chemie-International Edition 41 (21), S. 4066 - 4069 (2002)

Declerck, N.; Machius, M.; Joyet, P.; Wiegand, G.; Huber, R.; Gaillardin, C.: Engineering the thermostability of Bacillus licheniformis alpha-amylase. Biologia 57 (Suppl. 11), S. 203 - 211 (2002)

Fischer, M.; Haase, I.; Feicht, R.; Richter, G.; Gerhardt, S.; Changeux, J. P.; Huber, R.; Bacher, A.: Biosynthesis of riboflavin - 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. European Journal of Biochemistry 269 (2), S. 519 - 526 (2002)

Gerhardt, S.; Haase, I.; Steinbacher, S.; Kaiser, J. T.; Cushman, M.; Bacher, A.; Huber, R.; Fischer, M.: The structural basis of riboflavion binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase. Journal of Molecular Biology 318, S. 1317 - 1329 (2002)

Kaiser, M.; Groll, M.; Renner, C.; Huber, R.; Moroder, L.: The core structure of TMC-95A is a promising lead for reversible proteasome inhibition. Angewandte Chemie-International Edition 41 (5), S. 780 - 783 (2002)

Song, H. K.; Mulrooney, S. B.; Huber, R.; Hausinger, R. P.: Crystal structure of Klebsiella aerogenes UreE, a nickel- binding metallochaperone for urease activation. Journal of Biological Chemistry 276 (52), S. 49359 - 49364 (2001)

Riedl, S. J.; Fuentes-Prior, P.; Renatus, M.; Kairies, N.; Krapp, S.; Huber, R.; Salvesen, G. S.; Bode, W.: Structural basis for the activation of human procaspase-7. Proceedings of the National Academy of Sciences of the United States of America 98 (26), S. 14790 - 14795 (2001)

Dorowski, A.; Hofmann, A.; Steegborn, C.; Boicu, M.; Huber, R.: Crystal Structure of Paprika Ferredoxin-NADP(+)Reductase – Implications for the Electron Transfer Pathway. J. Biol. Chem. 276 (12), S. 9253 - 9263 (2001)

Bergner, A.; Oganessyan, V.; Muta, T.; Iwanaga, S.; Typke, D.; Huber, R.; Bode, W.: Crystal structure of coagulogen, the clotting protein from horseshoe crab - a structural homologue of nerve growth factor. EMBO Journal 15 (24), S. 6789 - 6797 (1996)

Stock, D.; Nederlof, P. M.; Seemüller, E.; Baumeister, W.; Huber, R.; Löwe, J.: Proteasome: from structure to function. Current Opinion in Biotechnology. 7 (4), S. 376 - 385 (1996)

Löwe, J.; Stock, D.; Jap, B.; Zwickl, P.; Baumeister, W.; Huber, R.: Crystal structure of the 20s proteasome from the archaeon t-acidophilum at 3.4 angstrom resolution. Science 268 (5210), S. 533 - 539 (1995)

Seemüller, E.; Lupas, A.; Stock, D.; Löwe, J.; Huber, R.; Baumeister, W.: Proteasome from thermoplasma acidophilum - a threonine protease. Science 268 (5210), S. 579 - 582 (1995)

Stock, D.; Ditzel, L.; Baumeister, W.; Huber, R.; Löwe, J.: Catalytic mechanism of the 20s proteasome of thermoplasma acidophilum revealed by x-ray crystallography. Cold Spring Harbor Symposia on Quantitative Biology 60, S. 525 - 532 (1995)