Publikationen von John A. G. Briggs

Klumpe, S.; Senti, K. A.; Beck, F.; Sachweh, J.; Hampoelz, B.; Ronchi, P.; Oorschot, V.; Brandstetter, M.; Yeroslaviz, A.; Briggs, J. A. G. et al.; Brennecke, J.; Beck, M.; Plitzko, J. M.: In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography. Cell 188 (8), S. 2094 - 2110.e18 (2025)

Stacey, J. C. V.; Hrebík, D.; Nand, E.; Shetty, S. D.; Qu, K.; Boicu, M.; Anders-Össwein, M.; Uchil, P. D.; Dick, R. A.; Mothes, W. et al.; Kräusslich, H.-G.; Müller, B.; Briggs, J. A. G.: The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation. Nature 640 (8057), S. 258 - 264 (2025)

Hastie, K. M.; Salie, Z. L.; Ke, Z.; Halfmann, P. J.; DeWald, L. E.; McArdle, S.; Grinyó, A.; Davidson, E.; Schendel, S. L.; Hariharan, C. et al.; Norris, M. J.; Yu, X.; Chennareddy, C.; Xiong, X.; Heinrich, M.; Holbrook, M. R.; Doranz, B.; Crozier, I.; Kawaoka, Y.; Branco, L. M.; Kuhn, J. H.; Briggs, J. A. G.; Worwa, G.; Davis, C. W.; Ahmed, R.; Saphire, E. O.: Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane. Nature Communications 16, 1293 (2025)

Peukes, J.; Dmitrieff, S.; Nédélec, F. J.; Briggs, J.: A physical model for M1-mediated influenza A virus assembly. Biophysical Journal 124 (1), S. 134 - 144 (2025)

Ke, Z.; Peacock, T. P.; Brown, J. C.; Sheppard, C. M.; Croll, T. I.; Kotecha, A.; Goldhill, D. H.; Barclay, W. S.; Briggs, J. A. G.: Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants. The EMBO Journal 43 (24), S. 6469 - 6495 (2024)

Xu, J.; Erlendsson, S.; Singh, M.; Holling, A.; Regier, M.; Ibiricu, I.; Einstein, J.; Hantak, M. P.; Day, G. S.; Piquet, A. L. et al.; Smith, T. L.; Clardy, S. L.; Whiteley, A. M.; Briggs, J. A. G.; Shepherd, J. D.; Feschotte, C.: PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome. Cell 187 (4), S. 831 - 845 (2024)

Banerjee, P.; Qu, K.; Briggs, J. A. G.; Voth, G. A.: Molecular dynamics simulations of HIV-1 matrix-membrane interactions at different stages of viral maturation. Biophysical Journal 123 (3), S. 389 - 406 (2024)

Highland, C. M.; Tan, A.; Ricana, C. L.; Briggs, J. A. G.; Dick, R. A.: Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18), e2220545120 (2023)

Taylor, R. J.; Tagiltsev, G.; Briggs, J. A. G.: The structure of COPI vesicles and regulation of vesicle turnover. FEBS Letters 597 (6), S. 819 - 835 (2023)

Gaynor, K. U. U.; Vaysburd, M.; Harman, M. A. J.; Albecka, A.; Jeffrey, P.; Beswick, P.; Papa, G.; Chen, L.; Mallery, D.; McGuinness, B. et al.; Van Rietschoten, K.; Stanway, S.; Brear, P.; Lulla, A.; Ciazynska, K.; Chang, V. T. T.; Sharp, J.; Neary, M.; Box, H.; Herriott, J.; Kijak, E.; Tatham, L.; Bentley, E. G. G.; Sharma, P.; Kirby, A.; Han, X.; Stewart, J. P. P.; Owen, A.; Briggs, J. A. G.; Hyvonen, M.; Skynner, M. J. J.; James, L. C. C.: Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2. Nature Communications 14 (1), 3852 (2023)

Stacey, J. C. V.; Tan, A.; Lu, J. M.; James, L. C.; Dick, R. A.; Briggs, J. A. G.: Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding. Proceedings of the National Academy of Sciences of the United States of America 120 (16), e222055712 (2023)

Zivanov, J.; Otón, J.; Ke, Z.; von Kügelgen, A.; Pyle, E.; Qu, K.; Morado, D.; Castaño-Díez, D.; Zanetti, G.; Bharat, T. A. et al.; Briggs, J. A. G.; Scheres, S. H.: A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0. eLife 11, e83724 (2022)

He, P.; Liu, B.; Gao, X.; Yan, Q.; Pei, R.; Sun, J.; Chen, Q.; Hou, R.; Li, Z.; Zhang, Y. et al.; Zhao, J.; Sun, H.; Feng, B.; Wang, Q.; Yi, H.; Hu, P.; Li, P.; Zhang, Y.; Chen, Z.; Niu, X.; Zhong, X.; Jin, L.; Liu, X.; Qu, K.; Ciazynska, K. A.; Carter, A. P.; Briggs, J. A. G.; Chen, J.; Liu, J.; Chen, X.; He, J.; Chen, L.; Xiong, X.: SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nature Microbiology 7, S. 1635 - 1649 (2022)

Qu, K.; Chen, Q.; Ciazynska, K. A.; Liu, B.; Zhang, X.; Wang, J.; He, Y.; Guan, J.; He, J.; Liu, T. et al.; Zhang, X.; Carter, A. P.; Xiong, X.; Briggs, J. A. G.: Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. PLoS Pathogens 18 (7), e1010583 (2022)

Meng, B.; Abdullahi, A.; Ferreira, I. A. T. M.; Goonawardane, N.; Saito, A.; Kimura, I.; Yamasoba, D.; Gerber, P. P.; Fatihi, S.; Rathore, S. et al.; Zepeda, S. K.; Papa, G.; Kemp, S. A.; Ikeda, T.; Toyoda, M.; Tan, T. S.; Kuramochi, J.; Mitsunaga, S.; Ueno, T.; Shirakawa, K.; Takaori-Kondo, A.; Brevini, T.; Mallery, D. L.; Charles, O. J.; Bowen, J. E.; Joshi, A.; Walls, A. C.; Jackson, L.; Martin, D.; Smith, K. G. C.; Bradley, J.; Briggs, J. A. G.; Choi, J.; Madissoon, E.; Meyer, K. B.; Mlcochova, P.; Ceron-Gutierrez, L.; Doffinger, R.; Teichmann, S. A.; Fisher, A. J.; Pizzuto, M. S.; de Marco, A.; Corti, D.; Hosmillo, M.; Lee, J. H.; James, L. C.; Thukral, L.; Veesler, D.; Sigal, A.; Sampaziotis, F.; Goodfellow, I. G.; Matheson, N. J.; Sato, K.; Gupta, R. K.: Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity. Nature 603 (7902), S. 706 - 714 (2022)

Yu, A.; Lee, E. M. Y.; Briggs, J. A. G.; Ganser-Pornillos, B. K.; Pornillos, O.; Voth, G. A.: Strain and rupture of HIV-1 capsids during uncoating. Proceedings of the National Academy of Sciences of the United States of America 119 (10), e2117781119 (2022)

Pak, A. J.; Yu, A.; Ke, Z.; Briggs, J. A. G.; Voth, G. A.: Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core. Nature Communications 13 (1), 1002 (2022)

Zaccai, N. R.; Kadlecova, Z.; Dickson, V. K.; Korobchevskaya, K.; Kamenicky, J.; Kovtun, O.; Umasankar, P. K.; Wrobel, A. G.; Kaufman, J. G. G.; Gray, S. R. et al.; Qu, K.; Evans, P. R.; Fritzsche, M.; Sroubek, F.; Hoening, S.; Briggs, J. A. G.; Kelly, B. T.; Owen, D. J.; Traub, L. M.: FCHO controls AP2's initiating role in endocytosis through a Ptdlns(4,5)P-2-dependent switch. Science Advances 8 (17), eahn2018 (2022)

Baxendale, H. E.; Wells, D.; Gronlund, J.; Nadesalingham, A.; Paloniemi, M.; Carnell, G.; Tonks, P.; Ceron-Gutierrez, L.; Ebrahimi, S.; Sayer, A. et al.; Briggs, J. A. G.; Ziong, X.; Nathan, J. A.; Grice, G.; James, L. C.; Luptak, J.; Pai, S.; Heeney, J. L.; Lear, S.; Doffinger, R.: Critical Care Workers Have Lower Seroprevalence of SARS-CoV-2 IgG Compared with Non-patient Facing Staff in First Wave of COVID19. Journal of Critical Care Medicine 7 (3), S. 199 - 210 (2021)

Carnell, G. W.; Ciazynska, K. A.; Wells, D. A.; Xiong, X.; Aguinam, E. T.; McLaughlin, S. H.; Mallery, D.; Ebrahimi, S.; Ceron-Gutierrez, L.; Asbach, B. et al.; Einhauser, S.; Wagner, R.; James, L. C.; Doffinger, R.; Heeney, J. L.; Briggs, J. A. G.; Parrish, C. R.: SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses. Journal of Virology 95 (15), e00203-21 (2021)