Publications of the Institute

Xu, R.; Li, K.; Chen, A.; Chen, Y.; Sheng, R.; Chen, C.; Qin, H.; Zhang, W.; Liu, Y.; Rodriguez, H. V. et al.; Kanaparti, D.; Zhu, B.: Responses of Soil Microbial Communities to Abandoned Paddy Fields With Different Fertilization Histories. Land Degradation & Development 36 (6), pp. 1820 - 1833 (2025)

Pesch, G.; Piseddu, I.; Gaertig, J.; Kramer, N.; Kramer, R.; Schulz, T. U.; Zwiebel, M.; Ledderose, S.; Retzlaff, J.; Eckstein, M. et al.; Schett, G.; Kammerbauer, C.; Schmitt, C.; Kumbrink, J.; Erdmann, M.; Kruis, W.; Dougan, M.; Mayerle, J.; French, L. E.; Vera, J.; Nordmann, T. M.; Mann, M.; Klauschen, F.; Anz, D.; Heinzerling, L.: Deep immune phenotyping reveals distinct immunopathogenesis in checkpoint inhibitor-induced colitis compared to ulcerative colitis. Cancer Immunology Research (2025)

Klumpe, S.; Senti, K. A.; Beck, F.; Sachweh, J.; Hampoelz, B.; Ronchi, P.; Oorschot, V.; Brandstetter, M.; Yeroslaviz, A.; Briggs, J. A. G. et al.; Brennecke, J.; Beck, M.; Plitzko, J. M.: In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography. Cell 188 (8), pp. 2094 - 2110.e18 (2025)

Kiss, L.; James, L. C.; Schulman, B. A.: UbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chains. Molecular Cell 85 (7), pp. 1467 - 1476 (2025)

Sewald, L.; Tabak, W. W. A.; Fehr, L.; Zolg, S.; Najdzion, M.; Verhoef, C. J. A.; Podlesainski, D.; Geiss-Friedlander, R.; Lammens, A.; Kaschani, F. et al.; Hellerschmied, D.; Huber, R.; Kaiser, M.: Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors. Nature Communications 16 (1), 3208 (2025)

Stacey, J. C. V.; Hrebík, D.; Nand, E.; Shetty, S. D.; Qu, K.; Boicu, M.; Anders-Össwein, M.; Uchil, P. D.; Dick, R. A.; Mothes, W. et al.; Kräusslich, H.-G.; Müller, B.; Briggs, J. A. G.: The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation. Nature 640 (8057), pp. 258 - 264 (2025)

Archer, D.; Pérez-Muñoz, M. E.; Tollenaar, S.; Veniamin, S.; Hotte, N.; Cheng, C. C.; Nieves, K.; Oh, J.-H.; Morceli, L.; Muncner, S. et al.; Barreda, D. R.; Krishnamoorthy, G.; Power, C.; van Pijkeren, J.-P.; Walter, J.: A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis. Cell Reports 44 (3), 115321 (2025)

Carvajal-Patiño, J. G.; Mallet, V.; Becerra, D.; Vasquez, L. F. N.; Oliver, C.; Waldispühl, J.: RNAmigos2: Accelerated structure-based RNA virtual screening with deep graph learning. Nature Communications 16 (1), 2799 (2025)

Pousa, S.; Ramos-Bermudez, P. E.; Besada, V.; Cabrales-Rico, A.; Cruz, O. G.; Garay, H. E.; Rodriguez-Mallon, A.; Zettl, K.; Wiśniewski, J. R.; Gonzalez, L. J.: Characterization by LC-MS/MS analysis of KLH vaccine conjugated with a tick antigen peptide. Analyst 150 (6), pp. 1091 - 1102 (2025)

Unterauer, E.; Schentarra, E.-M.; Jevdokimenko, K.; Boushehri, S. S.; Marr, C.; Opazo, F.; Fornasiero, E. F.; Jungmann, R.: Protocol for SUM-PAINT spatial proteomic imaging generating neuronal architecture maps in rat hippocampal neurons. Star Protocols 6 (1), 103637 (2025)

Becker, M.; Kälin, S.; Neubig, A. H.; Lauber, M.; Opaleva, D.; Hipp, H.; Salb, V. K.; Ott, V. B.; Legutko, B.; Kälin, R. E. et al.; Hippich, M.; Scherm, M. G.; Nascimento, L. F. R.; Serr, I.; Hosp, F.; Nikolaev, A.; Mohebiany, A.; Krueger, M.; Flachmeyer, B.; Pfaffl, M. W.; Haase, B.; Yi, C. X.; Dietzen, S.; Bopp, T.; Woods, S. C.; Waisman, A.; Weigmann, B.; Mann, M.; Tschöp, M. H.; Daniel, C.: Regulatory T cells in the mouse hypothalamus control immune activation and ameliorate metabolic impairments in high-calorie environments. Nature Communications 16, 2744 (2025)

Gupta, M.; Kurth, T.; Heinemann, F.; Schwille, P.; Keil, S.; Knopf, F.; Brand, M.: Fine-tuning of Fgf8 morphogen gradient by heparan sulfate proteoglycans in the extracellular matrix. Biophysical Journal 124 (6), pp. 996 - 1010 (2025)

Jerala, R.; Vidmar, S.; Šmidlehner, T.; Aupič, J.; Strmšek, Ž.; Ljubetič, A.; Xiao, F.; Hu, G.; Liu, C.; Beck, F. et al.; Erdmann, P. S.: Beyond Dimerization: Harnessing Tetrameric Coiled‐Coils for Nanostructure Assembly. Angewandte Chemie International Edition 64 (12), e202422075 (2025)

Kriebisch, C. M. E.; Bantysh, O.; Pellejero, L. B.; Belluati, A.; Bertosin, E.; Dai, K.; de Roy, M.; Fu, H. L.; Galvanetto, N.; Gibbs, J. M. et al.; Gomez, S. S.; Granatelli, G.; Griffo, A.; Guix, M.; Gurdap, C. O.; Harth-Kitzerow, J.; Haugerud, I. S.; Häfner, G.; Jaiswal, P.; Javed, S.; Karimi, A.; Kato, S.; Kriebisch, B. A. K.; Laha, S.; Lee, P. W.; Lipinski, W. P.; Matreux, T.; Michaels, T. C. T.; Poppleton, E.; Ruf, A.; Slootbeek, A. D.; Smokers, I. B. A.; Soria-Carrera, H.; Sorrenti, A.; Stasi, M.; Stevenson, A.; Thatte, A.; Tran, M.; van Haren, M. H. I.; Vuijk, H. D.; Wickham, S. F. J.; Zambrano, P.; Adamala, K. P.; Alim, K.; Andersen, E. S.; Bonfio, C.; Braun, D.; Frey, E.; Gerland, U.; Huck, W. T. S.; Jülicher, F.; Laohakunakorn, N.; Mahadavan, L.; Otto, S.; Saenz, J.; Schwille, P.; Göpfrich, K.; Weber, C. A.; Boekhoven, J.: A roadmap toward the synthesis of life. Chem 11 (3), 102399 (2025)

Zheng, X.; Mund, A.; Mann, M.: Deciphering functional tumor-immune crosstalk through highly multiplexed imaging and deep visual proteomics. Molecular Cell 85 (5), pp. 1008 - 1023 (2025)

Niu, L. L.; Stinson, S. E.; Holm, L. A.; Lund, M. A. V.; Fonvig, C. E.; Cobuccio, L.; Meisner, J.; Juel, H. B.; Fadista, J.; Thiele, M. et al.; Krag, A.; Holm, J.-C.; Rasmussen, S.; Hansen, T.; Mann, M.: Plasma proteome variation and its genetic determinants in children and adolescents. Nature Genetics 57 (3), pp. 635 - 646 (2025)

Guo, T.; Steen, J. A.; Mann, M.: Mass-spectrometry-based proteomics: from single cells to clinical applications. Nature 638 (8052), pp. 901 - 911 (2025)

Ravenhill, B. J.; Oliveira, M.; Wood, G.; Di, Y.; Kite, J.; Wang, X.; Davies, C. T. R.; Lu, Y.; Antrobus, R.; Elliott, G. et al.; Irigoyen, N.; Hughes, D. J.; Lyons, P. A.; Chung, B.; Borner, G. H. H.; Weekes, M. P.: Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11. Cell Reports 44 (2), 115263 (2025)

Muhar, M. F.; Farnung, J.; Cernakova, M.; Hofmann, R.; Henneberg, L. T.; Pfleiderer, M. M.; Denoth-Lippuner, A.; Kalčic, F.; Nievergelt, A. S.; Peters Al-Bayati, M. et al.; Sidiropoulos, N. D.; Beier, V.; Mann, M.; Jessberger, S.; Jinek, M.; Schulman, B.; Bode, J. W.; Corn, J. E.: C-terminal amides mark proteins for degradation via SCF–FBXO31. Nature 638, pp. 519 - 527 (2025)

Weck, J. M.; Heuer-Jungemann, A.: Fully addressable designer superstructures assembled from one single modular DNA origami. Nature Communications 16 (1), 1556 (2025)