Publikationen von Ralph T. Böttcher

Heim, J. B.; Squirewell, E. J.; Neu, A.; Zocher, G.; Sominidi-Damodaran, S.; Wyles, S. P.; Nikolova, E.; Behrendt, N.; Saunte, D. M.; Lock-Andersen, J. et al.; Gaonkar, K. S.; Yan, H.; Sarkaria, J. N.; Krendel, M.; van Deursen, J.; Sprangers, R.; Stehle, T.; Böttcher, R. T.; Lee, J.-H.; Ordog, T.; Meves, A.: Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proceedings of the National Academy of Sciences of the United States of America 114 (15), S. 3933 - 3938 (2017)

Jiang, C.; Ding, Z.; Joy, M.; Chakraborty, S.; Kim, S. H.; Bottcher, R.; Condeelis, J.; Singh, S.; Roy, P.: A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells. Cell Cycle 16 (24), S. 2366 - 2373 (2017)

Pick, R.; Begandt, D.; Stocker, T. J.; Salvermoser, M.; Thome, S.; Böttcher, R. T.; Montanez, E.; Harrison, U.; Forne, I.; Khandoga, A. G. et al.; Coletti, R.; Weckbach, L. T.; Brechtefeld, D.; Haas, R.; Imhof, A.; Massberg, S.; Sperandio, M.; Walzog, B.: Coronin 1A, a novel player in integrin biology, controls neutrophil trafficking in innate immunity. Blood 130 (7), S. 847 - 858 (2017)

Mana, G.; Clapero, F.; Panieri, E.; Panero, V.; Böttcher, R. T.; Tseng, H.-Y.; Saltarin, F.; Astanina, E.; Wolanska, K. I.; Morgan, M. R. et al.; Humphries, M. J.; Santoro, M. M.; Serini, G.; Valdembri, D.: PPFIA1 drives active alpha 5 beta 1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nature Communications 7, 13546 (2016)

Deuschle, E.; Keller, B.; Siegfried, A.; Manncke, B.; Spaeth, T.; Köberle, M.; Drechsler-Hake, D.; Reber, J.; Böttcher, R. T.; Autenrieth, S. E. et al.; Autenrieth, I. B.; Bohn, E.; Schütz, M.: Role of beta 1 integrins and bacterial adhesins for Yop injection into leukocytes in Yersinia enterocolitica systemic mouse infection. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY 306 (2), S. 77 - 88 (2016)

Theodosiou, M.; Widmaier, M.; Böttcher, R. T.; Rognoni, E.; Veelders, M.; Bharadwaj, M.; Lambacher, A.; Austen, K.; Müller, D. J.; Zent, R. et al.; Fässler, R.: Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. ELIFE 5, e10130 (2016)

Yazlovitskaya, E. M.; Tseng, H.-Y.; Viquez, O.; Tu, T.; Mernaugh, G.; McKee, K. K.; Riggins, K.; Quaranta, V.; Pathak, A.; Carter, B. D. et al.; Yurchenco, P.; Sonnenberg, A.; Böttcher, R. T.; Pozzi, A.; Zent, R.: Integrin alpha 3 beta 1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. MOLECULAR BIOLOGY OF THE CELL 26 (10), S. 1857 - 1874 (2015)

Rognoni, E.; Widmaier, M.; Jakobson, M.; Ruppert, R.; Ussar, S.; Katsougkri, D.; Böttcher, R. T.; Lai-Cheong, J. E.; Rifkin, D. B.; McGrath, J. A. et al.; Fässler, R.: Kindlin-1 controls Wnt and TGF-beta availability to regulate cutaneous stem cell proliferation. Nature Medicine 20 (4), S. 350 - 359 (2014)

Böttcher, R. T.; Fässler, R.: Membrane tension drives ligand-independent integrin signaling. EMBO JOURNAL 33 (21), S. 2439 - 2441 (2014)

Montani, L.; Buerki-Thurnherr, T.; de Faria, J. P.; Pereira, J. A.; Dias, N. G.; Fernandes, R.; Goncalves, A. F.; Braun, A.; Benninger, Y.; Böttcher, R. T. et al.; Costell, M.; Nave, K.-A.; Franklin, R. J. M.; Meijer, D.; Suter, U.; Relvas, J. B.: Profilin 1 is required for peripheral nervous system myelination. DEVELOPMENT 141 (7), S. 1553 - 1561 (2014)

Tseng, H.-Y.; Thorausch, N.; Ziegler, T.; Meves, A.; Fässler, R.; Böttcher, R. T.: Sorting Nexin 31 Binds Multiple beta Integrin Cytoplasmic Domains and Regulates beta 1 Integrin Surface Levels and Stability. JOURNAL OF MOLECULAR BIOLOGY 426 (18), S. 3180 - 3194 (2014)

Zheng, J.; Lu, Z.; Kocabas, F.; Böttcher, R. T.; Costell, M.; Kang, X.; Liu, X.; DeBerardinis, R. J.; Wang, Q.; Chen, G.-Q. et al.; Sadek, H.; Zhang, C. C.: Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow. BLOOD 123 (7), S. 992 - 1001 (2014)

Meves, A.; Stremmel, C.; Böttcher, R. T.; Fässler, R.: beta 1 Integrins with Individually Disrupted Cytoplasmic NPxY Motifs Are Embryonic Lethal but Partially Active in the Epidermis. JOURNAL OF INVESTIGATIVE DERMATOLOGY 133 (12), S. 2722 - 2731 (2013)

Legate, K. R.; Montag, D.; Böttcher, R. T.; Takahashi, S.; Fässler, R.: Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type I gamma in vivo. JOURNAL OF CELL SCIENCE 125 (23), S. 5636 - 5646 (2012)

Kullmann, J. A.; Neumeyer, A.; Wickertsheim, I.; Böttcher, R. T.; Costell, M.; Deitmer, J. W.; Witke, W.; Friauf, E.; Rust, M. B.: PURKINJE CELL LOSS AND MOTOR COORDINATION DEFECTS IN PROFILIN1 MUTANT MICE. Neuroscience 223, S. 355 - 364 (2012)

Miyajima, D.; Hayata, T.; Suzuki, T.; Hemmi, H.; Nakamoto, T.; Notomi, T.; Amagasa, T.; Böttcher, R. T.; Costell, M.; Fässler, R. et al.; Ezura, Y.; Noda, M.: Profilin1 Regulates Sternum Development and Endochondral Bone Formation. Journal of Biological Chemistry 287 (40), S. 33545 - 33553 (2012)

Böttcher, R. T.; Stremmel, C.; Meves, A.; Meyer, H.; Widmaier, M.; Tseng, H. Y.; Fässler, R.: Sorting nexin 17 prevents lysosomal degradation of beta(1) integrins by binding to the beta(1)-integrin tail. Nature Cell Biology 14 (6), S. 584 - 592 (2012)

Azimifar, S. B.; Böttcher, R. T.; Zanivan, S.; Grashoff, C.; Krüger, M.; Legate, K. R.; Mann, M.; Fässler, R.: Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor. Journal of Cell Science 125 (2), S. 435 - 448 (2012)

Goerlich, A.; Zimmermann, A. M.; Schober, D.; Böttcher, R. T.; Sassoe-Pognetto, M.; Friauf, E.; Witke, W.; Rust, M. B.: Preserved Morphology and Physiology of Excitatory Synapses in Profilin1-Deficient Mice. PLoS ONE 7 (1), e30068, S. [1] - [8] (2012)

Stremmel, C.; Boettcher, R.; Meves, A.; Fässler, R.: Novel functions of kindlin2 and the beta 1 integrin threonine motif. Journal of Vascular Research 48 (Suppl. 1), S. 179 - 179 (2011)