Publikationen von R. Huber

Sichler, K.; Hopfner, K. P.; Kopetzki, E.; Huber, R.; Bode, W.; Brandstetter, H.: The influence of residue 190 in the S1 site of trypsin-like serine proteases on substrate selectivity is universally conserved. FEBS Letters 530 (1-3), S. 220 - 224 (2002)

Goettig, P.; Groll, M.; Kim, J. S.; Huber, R.; Brandstetter, H.: Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism. EMBO Journal 21 (20), S. 5343 - 5352 (2002)

Cushman, M.; Yang, D. L.; Mihalic, J. T.; Chen, J. H.; Gerhardt, S.; Huber, R.; Fischer, M.; Kis, K.; Bacher, A.: Incorporation of an amide into 5-phosphonoalkyl-6-D- ribitylaminopyrimidinedione lumazine synthase inhibitors results in an unexpected reversal of selectivity for riboflavin synthase vs lumazine synthase. Journal of Organic Chemistry 67 (20), S. 6871 - 6877 (2002)

Einsle, O.; Messerschmidt, A.; Huber, R.; Kroneck, P. M. H.; Neese, F.: Mechanism of the six-electron reduction of nitrite to ammonia by cytochrome c nitrite reductase. Journal of the American Chemical Society 124 (39), S. 11737 - 11745 (2002)

Gerhardt, S.; Schott, A. K.; Kairies, N.; Cushman, M.; Illarionov, B.; Eisenreich, W.; Bacher, A.; Huber, R.; Steinbacher, S.; Fischer, M.: Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8- ribityllumazine. Structure 10 (10), S. 1371 - 1381 (2002)

Sichler, K.; Banner, D. W.; D'Arcy, A.; Hopfner, K. P.; Huber, R.; Bode, W.; Kresse, G. B.; Kopetzki, E.; Brandstetter, H.: Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions. Journal of Molecular Biology 322 (3), S. 591 - 603 (2002)

Steiner, T.; Kaiser, J. T.; Marinkovic, S.; Huber, R.; Wahl, M. C.: Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities. EMBO Journal 21 (17), S. 4641 - 4653 (2002)

Raaijmakers, H.; Macieira, S.; Dias, J. M.; Teixeira, S.; Bursakov, S.; Huber, R.; Moura, J. J. G.; Moura, I.; Romao, M. J.: Gene sequence and the 1.8 angstrom crystal structure of the tungsten-containing formate dehydrogenase from Desulfolvibrio gigas. Structure 10 (9), S. 1261 - 1272 (2002)

Garrido-Franco, M.; Laber, B.; Huber, R.; Clausen, T.: Enzyme-ligand complexes of pyridoxine 5 -phosphate synthase: Implications for substrate binding and catalysis. Journal of Molecular Biology 321 (4), S. 601 - 612 (2002)

Atzenhofer, W.; Regelsberger, G.; Jacob, U.; Peschek, G. A.; Furtmüller, P. G.; Huber, R.; Obinger, C.: The 2.0 angstrom resolution structure of the catalytic portion of a cyanobacterial membrane-bound manganese superoxide dismutase. Journal of Molecular Biology 321 (3), S. 479 - 489 (2002)

Marquardt, U.; Zettl, F.; Huber, R.; Bode, W.; Sommerhoff, C. P.: The crystal structure of human alpha 1-tryptase reveals a blocked substrate-binding region. Journal of Molecular Biology 321 (3), S. 491 - 502 (2002)

Braun, N.; Meining, W.; Hars, U.; Fischer, M.; Ladenstein, R.; Huber, R.; Bacher, A.; Weinkauf, S.; Bachmann, L.: Formation of metal nanoclusters on specific surface sites of protein molecules. Journal of Molecular Biology 321 (2), S. 341 - 353 (2002)

Cushman, M.; Yang, D. L.; Gerhardt, S.; Huber, R.; Fischer, M.; Kis, K.; Bacher, A.: Design, synthesis, and evaluation of 6-carboxyalkyl and 6- phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase. Journal of Organic Chemistry 67 (16), S. 5807 - 5816 (2002)

Jozic, D.; Bourenkow, G.; Bartunik, H.; Scholze, H.; Dive, V.; Henrich, B.; Huber, R.; Bode, W.; Maskos, K.: Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides. Structure 10 (8), S. 1097 - 1106 (2002)

Cha, H. J.; Kopetzki, E.; Huber, R.; Lanzendörfer, M.; Brandstetter, H.: Structural basis of the adaptive molecular recognition by MMP9. Journal of Molecular Biology 320 (5), S. 1065 - 1079 (2002)

Brandstetter, H.; Kim, J. S.; Groll, M.; Göttig, P.; Huber, R.: Structural basis for the processive protein degradation by tricorn protease. Biological Chemistry 383 (7-8), S. 1157 - 1165 (2002)

Comellas-Bigler, M.; Fuentes-Prior, P.; Maskos, K.; Huber, R.; Oyama, H.; Uchida, K.; Dunn, B. M.; Oda, K.; Bode, W.: The 1.4 angstrom crystal structure of kumamolysin: A thermostable serine-carboxyl-type proteinase. Structure 10 (6), S. 865 - 876 (2002)

Ramachandran, R.; Hartmann, C.; Song, H. K.; Huber, R.; Bochtler, M.: Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY). Proceedings of the National Academy of Sciences of the United States of America 99 (11), S. 7396 - 7401 (2002)

Seifert, M. H. J.; Breitenlechner, C. B.; Bossemeyer, D.; Huber, R.; Holak, T. A.; Engh, R. A.: Phosphorylation and flexibility of cyclic-AMP-dependent protein kinase (PKA) using P-31 NMR Spectroscopy. Biochemistry 41 (19), S. 5968 - 5977 (2002)

Than, M. E.; Henrich, S.; Huber, R.; Ries, A.; Mann, K.; Kühn, K.; Timpl, R.; Bourenkov, G. P.; Bartunik, H. D.; Bode, W.: The 1.9-angstrom crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link. Proceedings of the National Academy of Sciences of the United States of America 99 (10), S. 6607 - 6612 (2002)