Publikationen von F. Ulrich Hartl

Leitman, J.; Hartl, F. U.; Lederkremer, G. Z.: Soluble forms of polyQ-expanded huntingtin rather than large aggregates cause endoplasmic reticulum stress. NATURE COMMUNICATIONS 4, 2753 (2013)

Hartl, F. U.; Hayer-Hartl, M.: THE FIRST CHAPERONIN. NATURE REVIEWS MOLECULAR CELL BIOLOGY 14 (10), S. 611 - 611 (2013)

Li, Z.; Hartl, F. U.; Bracher, A.: Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle. NATURE STRUCTURAL & MOLECULAR BIOLOGY 20 (8), S. 929 - 935 (2013)

Park, S.-H.; Kukushkin, Y.; Gupta, R.; Chen, T.; Konagai, A.; Hipp, M. S.; Hayer-Hartl, M.; Hartl, F. U.: PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone. Cell 154 (1), S. 134 - 145 (2013)

Rüßmann, F.; Stemp, M. J.; Mönkemeyer, L.; Etchells, S. A.; Bracher, A.; Hartl, F.-U.: Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109 (52), S. 21208 - 21215 (2012)

Herzog, F.; Kahraman, A.; Boehringer, D.; Mak, R.; Bracher, A.; Walzthoeni, T.; Leitner, A.; Beck, M.; Hartl, F.-U.; Ban, N. et al.; Malmstroem, L.; Aebersold, R.: Structural Probing of a Protein Phosphatase 2A Network by Chemical Cross-Linking and Mass Spectrometry. SCIENCE 337 (6100), S. 1348 - 1352 (2012)

Tsai, Y. C. C.; Mueller-Cajar, O.; Saschenbrecker, S.; Hartl, F. U.; Hayer-Hartl, M.: Chaperonin Cofactors, Cpn10 and Cpn20, of Green Algae and Plants Function as Hetero-oligomeric Ring Complexes. Journal of Biological Chemistry 287 (24), S. 20471 - 20481 (2012)

Leitner, A.; Joachimiak, L. A.; Bracher, A.; Mönkemeyer, L.; Walzthoeni, T.; Chen, B.; Pechmann, S.; Holmes, S.; Cong, Y.; Ma, B. X. et al.; Ludtke, S.; Chiu, W.; Hartl, F. U.; Aebersold, R.; Frydman, J.: The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT. Structure 20 (5), S. 814 - 825 (2012)

Calloni, G.; Chen, T.; Schermann, S. M.; Chang, H.-c.; Genevaux, P.; Agostini, F.; Gaetano Tartaglia, G.; Hayer-Hartl, M.; Hartl, F. U.: DnaK Functions as a Central Hub in the E. coli Chaperone Network. CELL REPORTS 1 (3), S. 251 - 264 (2012)

Lamond, A. I.; Uhlen, M.; Horning, S.; Makarov, A.; Robinson, C. V.; Serrano, L.; Hartl, F. U.; Baumeister, W.; Werenskiold, A. K.; Andersen, J. S. et al.; Vorm, O.; Linial, M.; Aebersold, R.; Mann, M.: Advancing Cell Biology Through Proteomics in Space and Time (PROSPECTS). Molecular & Cellular Proteomics 11 (Special Issue: Prospects in Space and Time), O112.017731, S. [1] - [12] (2012)

Sharma, K.; Vabulas, R. M.; Macek, B.; Pinkert, S.; Cox, J.; Mann, M.; Hartl, F. U.: Quantitative Proteomics Reveals That Hsp90 Inhibition Preferentially Targets Kinases and the DNA Damage Response. Special Issue: Prospects in Space and Time, M111.014654, S. [1] - [12] (2011)

Stotz, M.; Mueller-Cajar, O.; Ciniawsky, S.; Wendler, P.; Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Structure of green-type Rubisco activase from tobacco. Nature Structural & Molecular Biology 18 (12), S. 1366 - 1370 (2011)

Mueller-Cajar, O.; Stotz, M.; Wendler, P.; Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Structure and function of the AAA(+) protein CbbX, a red-type Rubisco activase. Nature 479 (7372), S. 194 - 199 (2011)

Gupta, R.; Kasturi, P.; Bracher, A.; Loew, C.; Zheng, M.; Villella, A.; Garza, D.; Hartl, F. U.; Raychaudhuri, S.: Firefly luciferase mutants as sensors of proteome stress. Nature Methods 8 (10), S. 879 - 886 (2011)

Hartl, F. U.: Chaperone-assisted protein folding: the path to discovery from a personal perspective. Nature Medicine 17 (10), S. 1206 - 1210 (2011)

Bracher, A.; Starling-Windhof, A.; Hartl, F. U.; Hayer-Hartl, M.: Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco. Nature Structural & Molecular Biology 18 (8), S. 875 - 880 (2011)

Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Molecular chaperones in protein folding and proteostasis. Nature 475 (7356), S. 324 - 332 (2011)

Resenberger, U. K.; Harmeier, A.; Woerner, A. C.; Goodman, J. L.; Müller, V.; Krishnan, R.; Vabulas, R. M.; Kretzschmar, H. A.; Lindquist, S.; Hartl, F. U. et al.; Multhaup, G.; Winklhofer, K. F.; Tatzelt, J.: The cellular prion protein mediates neurotoxic signalling of beta-sheet-rich conformers independent of prion replication. EMBO Journal 30 (10), S. 2057 - 2070 (2011)

Vabulas, R. M.; Hartl, F. U.: Aberrant protein interactions in amyloid disease. Cell Cycle 10 (10), S. 1512 - 1513 (2011)

Olzscha, H.; Schermann, S. M.; Woerner, A. C.; Pinkert, S.; Hecht, M. H.; Tartaglia, G. G.; Vendruscolo, M.; Hayer-Hartl, M.; Hartl, F. U.; Vabulas, R. M.: Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions. Cell 144 (1), S. 67 - 78 (2011)