Gassler, J.*, Kobayashi, W.*, Gáspár, I.*, Ruangroengkulrith, S.*, Mohanan, A., Gómez Hernández, L.,  Kravchenko, P., Kümmecke, M., Lalic, A., Rifel, N., Ashburn, R., Zaczek, M., Vallot, A., Cuenca Rico, L.,  Ladstätter, S., Tachibana, K. (2022). Zygotic genome activation by the totipotency pioneer factor Nr5a2.  Science Nov.24,  DOI: 10.1126/science.abn7478



Dequeker, B.J.H.*, Scherr M.J.*, Brandão, HB., Gassler, J., Powell, S., Gaspar, I., Flyamer, I.M., Lalic A., Tang, W., Stocsits, R., Davidson, I.F., Peters, J.M., Duderstadt, K.E., Mirny, L.A., Tachibana, K. (2022). MCM complexes are barriers that restrict cohesin-mediated loop extrusion. Nature 606(7912):197-203. DOI: 10.1038/s41586-022-04730-0

• Spotlight: 


Chatzidaki, E.E., Powell, S., Dequeker ,B.J.H., Gassler, J., Silva, M.C.C., Tachibana, K. (2021). Ovulation suppression protects against chromosomal abnormalities in mouse eggs at advanced maternal age. Curr.Biol. 31(18):4038-4051.e7    DOI: 10.1016/j.cub.2021.06.076

• Dispatch: Baumann, K., (2021) Nat. Rev. Mol. Cell Biol. 22, 586


Flyamer, I.M.*, Gassler, J.*, Imakaev, M.*, Brandão, H.B., Ulianov, S. V., Abdennur, N., Razin, S. V., Mirny, L.A., Tachibana-Konwalski, K. (2017). Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition. Nature 544, 110–114.   Doi: 10.1038/nature21711

• Research Highlight: Perdigoto, C. (2017). Nat. Rev. Genet. 18, 327.
• Highlighted in: Akst, J. (2017). The Scientist. December, 28-35. Cover story.
• Recommended in F1000 Prime as being of special significance in its field.


Gassler, J.*, Brandão, H.B.*, Imakaev, M., Flyamer, I.M., Ladstätter, S., Bickmore, W.A., Peters, J., Mirny, L.A., Tachibana, K. (2017). A mechanism of cohesindependent loop extrusion organizes zygotic genome architecture. EMBO J. 36, 3600–3618.   Doi: 10.15252/embj.201798083

• News & Views: Haarhuis, J.H.I., and Rowland, B.D. (2017). EMBO J. 36, 3549-3551.


Ladstätter, S., and Tachibana-Konwalski, K. (2016). A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming. Cell 167, 1774–1787.   Doi: 10.1016/j.cell.2016.11.009

• Preview: Zou, L. (2016). Cell 167, 1676- 1678.
• Highlighted in: Akst, J. (2017). The Scientist. December, 28-35. Cover story.
• 2016 Best Paper Award by the Austrian Academy of Sciences






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