Pioneer factor Nr5a2 (red) binds to the still inactive DNA wrapped around histones (gray), of a fertilized egg cell. Thereby, it awakens the genome. Now genes can be read that are necessary for the development of an embryo.

Researchers at the Max Planck Institute of Biochemistry have discovered that the pioneer factor Nr5a2 awakens the inactive genome in the early embryo. more

Prions induce toxic Huntingtin oligomers

A research team at the MPIB was able to identify the toxic form of the Huntingtin protein, which plays a crucial role in Huntington's disease, in a yeast model system. more

Petra Schwille

Petra Schwille, Director at the MPI of Biochemistry in Martinsried, is awarded the Otto Warburg Medal 2021 in recognition of her outstanding research work. more

Science Award for Max Planck Director Elena Conti

Elena Conti, Director at the MPI of Biochemistry in Martinsried receives prestigious Aminoff Prize from the Royal Swedish Academy of Science.

New method for early diagnosis of liver diseases by proteomics

A German-Danish research team led by Matthias Mann has developed a new screening method to identify alcohol-related liver diseases at an early stage through mass spectromy based proteomics. more

Deep Visual Proteomics concept and workflow

A German-Danish research team has developed the groundbreaking "Deep Visual Proteomics" technology. It provides cell-specific, protein-based information and helps to analyze cancer diseases.

For efficient packaging, DNA is placed in loops. The cohesin ring (pink) forms the basis for the loop. The protein complex MCM (yellow) limits the loop formation.

Researchers at the MPI of Biochemistry have discovered that the protein complex MCM has an unexpected influence on the three-dimensional organization of DNA.

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