Manajit Hayer-Hartl

Manajit Hayer-Hartl

Research Group Chaperonin-assisted Protein Folding

Protein Folding and Assembly, Rubisco, GroEL and GroES, Mass Spectrometry

Proteins can only fulfill their tasks in their correct three-dimensional structure. Cellular chaperones are responsible for the correct folding in the cell. However, they can also help scientists to artificially produce important proteins in the test tube. Manajit Hayer-Hartl and her research group "Chaperonin-mediated protein folding" have already succeeded in doing this for the key protein of photosynthesis "RuBisCO". The complex structure of RuBisCO (16 subunits) made it impossible to produce a functional version of the protein in the test tube. Using chaperones and helper proteins, the researchers have succeeded in producing a functional RuBisCO complex.



FASEB Science Research Conference 2020
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