Publications

Kamps, J.; Yuste-Checa, P.; Mamashli, F.; Schmitz, M.; Herrera, M. G.; da Silva Correia, S. M.; Gogte, K.; Bader, V.; Zerr, I.; Hartl, F. U. et al.; Bracher, A.; Winklhofer, K. F.; Tatzelt, J.: Regulated Proteolysis Induces Aberrant Phase Transition of Biomolecular Condensates into Aggregates: A Protective Role for the Chaperone Clusterin. Journal of Molecular Biology 436 (23), 168839 (2024)

Wales, T. E.; Pajak, A.; Roeselova, A.; Shivakumaraswamy, S.; Howell, S.; Kjaer, S.; Hartl, F. U.; Engen, J. R.; Balchin, D.: Resolving chaperone-assisted protein folding on the ribosome at the peptide level. Nature Structural & Molecular Biology 31 (12), pp. 1888 - 1897 (2024)

Wagner, J.; Carvajal Alvarez, A. I.; Bracher, A.; Beck, F.; Wan, W.; Bohn, S.; Körner, R.; Baumeister, W.; Fernandez-Busnadiego, R.; Hartl, F. U.: Visualizing chaperonin function in situ by cryo-electron tomography. Nature 633 (8029), pp. 459 - 464 (2024)

Krainer, G.; Jacquat, R. P. B.; Schneider, M. M.; Welsh, T. J.; Fan, J.; Peter, Q. A. E.; Andrzejewska, E. A.; Sneideriene, G.; Czekalska, M. A.; Ausserwoeger, H. et al.; Chai, L.; Arter, W. E.; Saar, K. L.; Herling, T. W.; Franzmann, T. M.; Kosmoliaptsis, V.; Alberti, S.; Hartl, F. U.; Lee, S. F.; Knowles, T. P. J.: Single-molecule digital sizing of proteins in solution. Nature Communications 15 (1), 7740 (2024)

Cairo, L. V.; Hong, X.; Mueller, M. B. D.; Yuste-Checa, P.; Jagadeesan, C.; Bracher, A.; Park, S.-H.; Hayer-Hartl, M.; Hartl, F. U.: Stress-dependent condensate formation regulated by the ubiquitin-related modifier Urm1. Cell 187 (17), pp. 4656 - 4673.e28 (2024)

Shimanovich, U.; Hartl, F. U.: Protein folding: From physico-chemical rules and cellular machineries of protein quality control to AI solutions. Proceedings of the National Academy of Sciences of the United States of America 121 (34), e2411135121 (2024)

Hipp, M. S.; Hartl, F. U.: Interplay of proteostasis capacity and Pprotein aggregation: Implications for cellular function and disease. Journal of Molecular Biology 436 (14), 168615 (2024)

Zhao, D. Y.; Bäuerlein, F. J. B.; Saha, I.; Hartl, F. U.; Baumeister, W.; Wilfling, F.: Autophagy preferentially degrades non-fibrillar polyQ aggregates. Molecular Cell 84 (10), pp. 1980 - 1994 (2024)