Publications

Young, J. C.; Agashe, V. R.; Siegers, K.; Hartl, F. U.: Pathways of chaperone-mediated protein folding in the cytosol. Nature Reviews Molecular Cell Biology 5 (10), pp. 781 - 791 (2004)

Hartl, U.: Role of molecular chaperones in de novo protein folding and in misfolding disease. Protein Science 13 (Suppl. Suppl. 1), p. 67 - 67 (2004)

Schaffar, G.; Breuer, P.; Boteva, R.; Behrends, C.; Tzvetkov, N.; Strippel, N.; Sakahira, H.; Siegers, K.; Hayer-Hartl, M.; Hartl, F. U.: Cellular toxicity of polyglutamine expansion proteins: Mechanism of transcription factor deactivation. Molecular Cell 15 (1), pp. 95 - 105 (2004)

Etchells, S. A.; Hartl, F. U.: The dynamic tunnel. Nature Structural & Molecular Biology 11 (5), pp. 391 - 392 (2004)

Agashe, V. R.; Guha, S.; Chang, H. C.; Genevaux, P.; Hayer-Hartl, M.; Stemp, M.; Georgopoulos, C.; Hartl, F. U.; Barral, J. M.: Function of trigger factor and DnaK in multidomain protein folding: Increase in yield at the expense of folding speed. Cell 117 (2), pp. 199 - 209 (2004)

Wochnik, G. M.; Young, J. C.; Schmidt, U.; Holsboer, F.; Hartl, F. U.; Rein, T.: Inhibition of GR-mediated transcription by p23 requires interaction with Hsp90. FEBS Letters 560 (1-3), pp. 35 - 38 (2004)

Barral, J. M.; Broadley, S. A.; Schaffar, G.; Hartl, F. U.: Roles of molecular chaperones in protein misfolding diseases. Seminars in Cell & Developmental Biology 15 (1), pp. 17 - 29 (2004)

Genevaux, P.; Keppel, F.; Schwager, F.; Langendijk-Genevaux, P. S.; Hartl, F. U.; Georgopoulos, C.: In vivo analysis of the overlapping functions of DnaK and trigger factor. EMBO Reports 5 (2), pp. 195 - 200 (2004)

Figueiredo, L.; Klunker, D.; Ang, D.; Naylor, D. J.; Kerner, M. J.; Georgopoulos, C.; Hartl, F. U.; Hayer-Hartl, M.: Functional characterization of an archaeal GroEL/GroES chaperonin system - Significance of substrate encapsulation. Journal of Biological Chemistry 279 (2), pp. 1090 - 1099 (2004)

Hartl, F. U.: Molecular chaperone action in polyglutamine aggregation disease. Biophysical Journal 86 (1), p. 166A - 166A (2004)