Publications
2022
Nadia M Huisjes, Thomas M Retzer, Matthias J Scherr, Rohit Agarwal, Lional Rajappa, Barbara Safaric, Anita Minnen, Karl E Duderstadt, Mars, a molecule archive suite for reproducible analysis and reporting of single-molecule properties from bioimages. ELife (2022). PMID: 36098381
Barbara Safaric, Erika Chacin, Matthias J Scherr, Lional T Rajappa, Christian Gebhardt, Christoph F Kurat, Thorben Cordes, Karl E Duderstadt, The fork protection complex recruits FACT to reorganize nucleosomes during replication. Nucleic Acids Res.(2022). PMID: 35061899
Matthias J.Scherr, Syafiq AbdWahab, DirkRemus, Karl E.Duderstadt, Mobile origin-licensing factors confer resistance to conflicts with RNA polymerase. Cell Reports (2022) . PMID: 35320708
Dequeker BJH, Scherr MJ, Brandão HB, Gassler J, Powell S, Gaspar I, Flyamer IM, Lalic A, Tang W, Stocsits R, Davidson IF, Peters JM, Duderstadt KE, Mirny LA, Tachibana K, MCM complexes are barriers that restrict cohesin-mediated loop extrusion. Nature (2022). PMID: 35585235
2021
Bauernfried S, Scherr MJ, Pichlmair A, Duderstadt KE, Hornung V. Human NLRP1 is a sensor for double-stranded RNA. Science (2021). PMID: 33243852
Marta Urbanska, Annemarie Lüdecke, Wim J. Walter, Antoine M. van Oijen, Karl E. Duderstadt, Stefan Diez, Highly-parallel microfluidics-based force spectroscopy on single cytoskeletal motors. Small (2021) PMID: 33759372
2020
Agarwal, R., Duderstadt, K.E. Multiplex flow magnetic tweezers reveal rare enzymatic events with single molecule precision. Nat Communications (2020). PMID: 32948754
2018
van Oijen, A.M., Duderstadt, K.E., Xiao, J., and Fishel, R. Plasticity of Multi-Protein Complexes. Journal of Molecular Biology (2018). PMID: 30102893
Hill, F.R., van Oijen, A.M., and Duderstadt, K.E. Detection of kinetic change points in piece-wise linear single molecule motion. The Journal of Chemical Physics (2018). PMID: 29604840
Duderstadt, K.E. How to Follow a Traveler with a Brownian Swagger. Biophysical Journal 115, 165 (2018). PMID: 29397876
Scherr, M.J., Safaric, B., and Duderstadt, K.E. Noise in the Machine: Alternative Pathway Sampling is the Rule During DNA Replication. Bioessays 77, 1700159 (2018). PMID: 29282758
2017
Lewis, J.S., Spenkelink, L.M., Jergic, S., Wood, E.A., Monachino, E., Horan, N.P., Duderstadt, K.E., Cox, M.M., Robinson, A., Dixon, N.E., and van Oijen, A. M. Single-molecule visualization of fast polymerase turnover in the bacterial replisome. Elife (2017). PMID: 28432790
2016
Duderstadt, K.E., Geertsema, H.J., Stratmann, S.A., Punter, C.M., Kulczyk, A.W., Richardson, C.C., and van Oijen, A.M. Simultaneous Real-Time Imaging of Leading and Lagging Strand Synthesis Reveals the Coordination Dynamics of Single Replisomes. Molecular Cell (2016). PMID: 27889453
Åberg, C., Duderstadt, K.E., and van Oijen, A.M. Stability versus exchange: a paradox in DNA replication. Nucleic Acids Research (2016). PMID: 27112565
2015
Geertsma, H.J., Duderstadt, K.E., and van Oijen, A.M. Single-molecule observation of prokaryotic DNA replication. Methods in Enzymology (2015). PMID: 25916715
2013
Duderstadt, K.E., Reyes-Lamothe, R., van Oijen, A.M., and Sherratt, D.J. Replication-Fork Dynamics. Cold Spring Harbor Perspectives in Biology (2013). PMID: 23881939
Duderstadt, K.E., and Berger, J.M. A structural framework for replication origin opening by AAA+ initiation factors. Curr. Opin. Struc. Biol (2013). PMID: 23266000
2011
Duderstadt, K.E., Chuang, K., and Berger, J.M. DNA stretching by bacterial initiators promotes replication origin opening. Nature (2011). PMID: 21964332
2010
Duderstadt, K.E., Mott, M.L., Crisona, N.J., Chuang, K., Yang, H., and Berger, J.M. Origin remodeling and opening in bacteria rely on distinct assembly states of the DnaA initiator. J. Biol. Chem (2010). PMID: 20595381
Dedeo, M.T., Duderstadt, K.E., Berger, J.M., and Francis, M. B. Nanoscale protein assemblies from a circular permutant of the tobacco mosaic virus. Nano Lett. (2010). PMID: 19924865
2008
Duderstadt, K.E., and Berger, J.M. AAA+ ATPases in the initiation of DNAreplication. Crit. Rev. Biochem. Mol. Biol. (2008). PMID: 18568846
van Petegem, F., Duderstadt, K.E., Clark, K.A., Wang M., and Minor, D.L., Jr. Alanine-scanning mutagenesis defines a conserved energetic hotspot in theCaValpha1 AID-CaVbeta interaction site that is critical for channel modulation. Structure (2008). PMID: 18275819
2007
Hanson, J.A., Duderstadt, K.E., Watkins, L. P., Bhattacharyya, S., Brokaw, J.,Chu, J.W., and Yang, H. Illuminating the mechanistic roles of enzyme conformational dynamics. Proc. Natl. Acad. Sci. U. S. A. (2007). PMID: 17989222
2006
Michelsen, K., Mrowiec, T., Duderstadt, K.E., Frey, S., Minor, D.L., Jr., Mayer, M.P., and Schwappach B. A multimeric membrane protein reveals 14-3-3 isoform specificity in forward transport in yeast. Traffic (2006). PMID: 16734667