Publications

(Publications are sorted by date of Epub)

2021

Bashirzadeh, Y.*, Wubshet, N.*, Litschel, T., Schwille, P., Liu, A.P.
(* contributed equally) 
Rapid Encapsulation of Reconstituted Cytoskeleton inside Giant Unilamellar Vesicles
JoVE (2021) Nov 10 doi: 10.3791/63332 [Epub ahead of print]

abstractURL

Schwille, P., Frohn, B. P.
Hidden protein functions and what they may teach to us
Trends in Cell Biol. (2021) doi.org/10.1016/j.tcb.2021.09.006 [Epub ahead of print]

abstractURL

Heermann, T.*, Steiert, F.*, Ramm, B., Hundt, N., Schwille, P.
(* contributed equally) 
Mass-sensitive particle tracking to elucidate the membrane-associated MinDE reaction cycle
Nat. Methods. (2021) Oct;18(10):1239-1246. doi: 10.1038/s41592-021-01260-x [Epub ahead of print]

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Bashirzadeh, Y., Redford, S.A., Lorpaiboon, C., Groaz, A., Litschel, T., Schwille, P., Hocky, G.M., Dinner, A., Liu, A.P.
Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture
Commun. Biol. (2021) Sep 28;4(1):1136. doi: 10.1038/s42003-021-02653-6 [Epub ahead of print]

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Merino-Salomón, A., Babl, L., Schwille, P.
Self-organized protein patterns: The MinCDE and ParABS systems
Curr Opin Cell Biol (2021) Aug 13;72:106-115. doi: 10.1016/j.ceb.2021.07.001 [Epub ahead of print]

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Chattopadhyay, M., Krok, E., Orlikowska, H., Schwille, P., Franquelim, H.G., Piatkowski, L.
Hydration Layer of Only a Few Molecules Controls Lipid Mobility in Biomimetic Membranes
J Am Chem Soc (2021) Aug 3, doi: 10.1021/jacs.1c04314. [Epub ahead of print]

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Stehr, F.*, Stein, J.*, Bauer, J., Niederauer, C., Jungmann, R., Ganzinger, K., Schwille, P.
(* contributed equally) 
Tracking single particles for hours via continuous DNA-mediated fluorophore exchange
Nat Commun (2021) Jul 21;12(1):4432. doi: 10.1038/s41467-021-24223-4. [Epub ahead of print]

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Burbaum, L., Schneider, J., Scholze, S., Böttcher, R.T., Baumeister, W., Schwille, P., Plitzko, J.M., Jasnin, M.
Molecular-scale visualization of sarcomere contraction within native cardiomyocytes
Nat Commun (2021), Jul 2;12(1):4086. doi: 10.1038/s41467-021-24049-0. [Epub ahead of print]

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Ramirez-Diaz, D.A., Merino-Salomón, A., Meyer, F., Heymann, M., Rivas, G., Bramkamp, M., Schwille P.
FtsZ induces membrane deformations via torsional stress upon GTP hydrolysis
Nat Commun (2021), Jun 03;12(1):3310. doi: 10.1038/s41467-021-23387-3. [Epub ahead of print]

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Kretschmer, S., Heermann, T., Tassinari, A., Glock, P., Schwille, P.
Increasing MinD’s Membrane Affinity Yields Standing Wave Oscillations and Functional Gradients on Flat Membranes
ACS Synth Biol (2021), Apr 21, DOI: 10.1021/acssynbio.0c00604 [Epub ahead of print]

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Litschel, T., Kelley, C.F., Holz, D., Adeli Koudehi, M., Vogel, S.K., Burbaum, L., Mizuno, N., Vavylonis, D., Schwille, P.
Reconstitution of contractile actomyosin rings in vesicles
Nat Commun (2021), Apr 15, DOI: 10.1038/s41467-021-22422-7 [Epub ahead of print]

abstractURL

Ramm, B.*, Goychuk, A.*, Khmelinskaia, A., Blumhardt, P., Eto, H., Ganzinger, K., Frey, E., Schwille, P.
(* contributed equally) 
A diffusiophoretic mechanism for ATP-driven transport without motor proteins
Nat Phys 17 (2021), 850-858, DOI: 10.1038/s41567-021-01213-3 [Epub 2021 Apr 05]

abstractURL

Eto, H., Franquelim, H.G., Heymann, M., Schwille, P.
Membrane-coated 3D architectures for bottom-up synthetic biology
Soft Matter 17 (2021), 5456-5466, DOI: 10.1039/D1SM00112D [Epub 2021 Mar 23]

abstractURL

Litschel, T., Schwille, P.
Protein Reconstitution Inside Giant Unilamellar Vesicles
Annu Rev Biophys 50 (2021), 525-48, DOI: 10.1146/annurev-biophys-100620-114132 [Epub 2021 Mar 05]

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Harrington, L., Fletcher, J.M., Heermann, T., Woolfson, D.N., Schwille, P.
De novo design of a reversible phosphorylation-dependent switch for membrane targeting
Nat Commun 12 (2021), 1472, DOI: 10.1038/s41467-021-21622-5 [Epub 2021 Mar 05]

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Fu, M., Franquelim, H.G., Kretschmer, S., Schwille, P.
Non‐equilibrium large‐scale membrane transformations driven by MinDE biochemical reaction cycles
Angew Chem Int Ed Engl. 60 (2021), 6496-6502, DOI: 10.1002/anie.202015184 [Epub 2021 Jan 26]

abstractURL
2016 - 2020


2020

Heermann, T., Franquelim, H.G., Glock, P., Harrington, L., Schwille, P.
Probing Biomolecular Interactions by a Pattern-Forming Peptide–Conjugate Sensor
Bioconjugate Chem (2020), Dec 14, DOI: 10.1021/acs.bioconjchem.0c00596 [Epub ahead of print]

abstract URL

Sun, H., Jia, H., Ramirez-Diaz, D.A., Budisa, N., Schwille, P.
Fine-tuning protein self-organization by orthogonal chemo-optogenetic tools
Angew Chem Int Ed Engl. 60 (2020), 4501-4506, DOI: 10.1002/anie.202008691 [Epub 2020 Nov 06]

abstract URL

Bashirzadeh, Y., Redford, S.A., Lorpaiboon, C., Groaz, A., Litschel, T., Schwille, P., Hocky, G.M., Dinner, A., Liu, A.P.
Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture
bioRxiv (2020), Oct 03, DOI: 10.1101/2020.10.03.322354 [Epub ahead of print]

abstract URL

Christ, S., Litschel, T., Schwille, P., Lipowsky, R.
Active shape oscillations of giant vesicles with cyclic closure and opening of membrane necks
Soft Matter 17 (2021), 319-330, DOI: 10.1039/d0sm00790k [Epub 2020 Sep 07]

abstract URL

Sohn, L.L., Schwille, P., Hierlemann, A., Tay, S., Samitier, J., Fu, J., Loskill, P.
How Can Microfluidic and Microfabrication Approaches Make Experiments More Physiologically Relevant?
Cell Syst (2020), Aug 29, DOI: 10.1016/j.cels.2020.07.003 [Epub ahead of print]

abstract URL

Ganzinger, K.A., Merino-Salomón, A., García-Soriano, D.A., Butterfield, A.N., Litschel, T., Siedler, F., Schwille P.
FtsZ reorganisation facilitates deformation of giant vesicles in microfluidic traps
Angew Chem Int Ed Engl (2020), Jul 31, DOI: 10.1002/anie.202001928 [Epub ahead of print]

abstract URL

Kelley, C.F., Litschel, T., Schumacher, S., Dedden, D., Schwille, P., Mizuno, N.
Phosphoinositides regulate force-independent interactions between talin, vinculin, and actin
eLife (2020), 9:e56110, DOI: 10.7554/eLife.56110 [Epub 2020 Jul 13]

abstract URL

Litschel, T., Kelley, C. F., Holz, D., Adeli Koudehi, M., Vogel, S. K., Burbaum, L., Mizuno, N., Vavylonis, D., Schwille, P.
Reconstitution of contractile actomyosin rings in vesicles
bioRxiv (2020), DOI: 10.1101/2020.06.30.180901 [Epub 2020 Jul 01]

abstract URL

Garcia-Soriano, D.A., Heermann, T., Raso, A., Rivas, G., Schwille, P.
The speed of FtsZ treadmilling is tightly regulated by membrane binding
Sci Rep 10 (2020), 10447. DOI: 10.1038/s41598-020-67224-x [Epub 2020 Jun 26]

abstract URL

Vogel, S.K., Wölfer, C., Ramirez-Diaz, D.A., Flassig, R.J., Sundmacher, K., Schwille, P.
Symmetry Breaking and Emergence of Directional Flows in Minimal Actomyosin Cortices
Cells (2020), Jun 9;9(6). pii: E1432. DOI: 10.3390/cells9061432 [Epub 2020 Jun 09]

abstract URL

Stehr, F*., Stein, J.*, Bauer, J., Niederauer, C., Jungmann, R., Ganzinger, K.A., Schwille, P.
(* contributed equally) 
Tracking Single Particles for Hours via Continuous DNA-mediated Fluorophore Exchange
bioRxiv (2020), DOI: 10.1101/2020.05.17.100354 [Epub 2020 May 17]

abstract URL

Franquelim, H.G., Dietz, H., Schwille, P.
Reversible membrane deformations by straight DNA origami filaments
Soft Matter 17 (2021), 276-287, DOI: 10.1039/D0SM00150C [Epub 2020 May 06]

abstract URL

Ramm, B., Goychuk, A., Khmelinskaia, A., Blumhardt, P., Ganzinger, K.A., Frey, E., Schwille, P.
ATP driven diffusiophoresis: active cargo transport without motor proteins
bioRxiv (2020), DOI: 10.1101/2020.05.01.072744 [Epub 2020 May 02]

abstract URL

Heermann, T., Ramm, B., Glaser, S., Schwille, P.
Local Self-Enhancement of MinD Membrane Binding in Min Protein Pattern Formation
J Mol Biol 432 (2020), 3191-3204, DOI: 10.1016/j.jmb.2020.03.012 [Epub 2020 Mar 19]

abstract URL

Jia, H., Litschel, T., Heymann, M., Eto, H., Franquelim, H.G., Schwille, P.
Shaping Giant Membrane Vesicles in 3D‐Printed Protein Hydrogel Cages
Small (2020), Feb 27, DOI: 10.1002/smll.201906259 [Epub ahead of print]

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2019

Glock, P., Brauns, F., Halatek, J., Frey, E., Schwille, P.
Design of biochemical pattern forming systems from minimal motifs
eLife (2019), 8:e48646, DOI: 10.7554/eLife.48646 [Epub 2019 Nov 26]

abstract URL

Schueder, F., Stein, J., Stehr, F., Auer, A., Sperl, B., Strauss, M.T., Schwille, P., Jungmann, R.
An order of magnitude faster DNA-PAINT imaging by optimized sequence design and buffer conditions
Nat Methods 16 (2019), 1101-1104, DOI: 10.1038/s41592-019-0584-7 [Epub 2019 Oct 07]

abstract URL

Stein, J.*, Stehr, F.*, Schueler, P., Blumhardt, P., Schueder, F., Mücksch, J., Jungmann, R., Schwille, P.
(* contributed equally) 
Towards absolute molecular numbers in DNA-PAINT
Nano Lett 19 (2019), 8182-8190 , DOI: 10.1021/acs.nanolett.9b03546 [Epub 2019 Sep 19]

abstract URL

Schwille, P.
Division in synthetic cells
Emerging Top Life Sci (2019), Sep 03, DOI: 10.1042/ETLS20190023 [Epub ahead of print]

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Morasch, M., Liu, J., Dirscherl, C.F., Ianeselli, A., Kühnlein, A., Le Vay, K., Schwintek, P., Islam, S., Corpinot, M.K., Scheu, B., Dingwell, D.B., Schwille, P., Mutschler, H., Powner, M.W., Mast, C.B., Braun, D.
Heated gas bubbles enrich, crystallize, dry, phosphorylate and encapsulate prebiotic molecules
Nature Chem (2019), Jul 29, DOI: 10.1038/s41557-019-0299-5 [Epub ahead of print]

abstract URL

Hürtgen, D., Mascarenhas, J., Heymann, M., Murray, S., Schwille, P., Sourjik, V.
Reconstitution and coupling of DNA replication and segregation in a biomimetic system
Chembiochem 20 (2019), 2633-2642, DOI: 10.1002/cbic.201900299 [Epub 2019 Jul 25]

abstract URL

Ramm, B., Heermann, T., Schwille, P.
The E. coli MinCDE system in the regulation of protein patterns and gradients
Cell Mol Life Sci 76 (2019) 4245-4273, DOI: 10.1007/s00018-019-03218-x [Epub 2019 Jul 17]

abstract URL

Jia, H., Schwille, P.
Bottom-up synthetic biology: reconstitution in space and time
Curr Opin Biotechnol 60 (2019) 179-187, DOI: 10.1016/j.copbio.2019.05.008 [Epub 2019 Jun 6]

abstract URL

Betaneli, V., Mücksch, J., Schwille, P.
Fluorescence Correlation Spectroscopy to Examine Protein-Lipid Interactions in Membranes
Methods Mol Biol 2003 (2019) 415-447, DOI: 10.1007/978-1-4939-9512-7_18 [Epub 2019 Jun 20]

abstract URL

Eto, H., Soga, N., Franquelim, H.G., Glock, P., Khmelinskaia, A., Kai, L., Heymann, M., Noji, H., Schwille, P.
Design of sealable custom-shaped cell mimicries based on self-assembled monolayers on CYTOP polymer
ACS Appl Mater Interfaces 11 (2019), 21372-21380, DOI: 10.1021/acsami.9b05073 [Epub 2019 May 28]

abstract URL

Kretschmer, S., Ganzinger, K.A., Franquelim, H.G., Schwille, P.
Synthetic cell division via membrane-transforming molecular assemblies
BMC Biol 17 (2019), 43, DOI: 10.1186/s12915-019-0665-1 [Epub 2019 May 24]

abstract URL

Schuster, P., Schwille, P.
Manfred Eigen (1927-2019)
Angew Chem Int Ed Engl 131 (2019), 9423-9424, DOI: 10.1002/ange.201904708 [Epub 2019 May 24]

abstract URL

Jia, H., Heymann, M., Härtel, T., Kai, L., Schwille, P.
Temperature-sensitive protein expression in protocells
Chem Commun 55 (2019) 6421-6424, DOI: 10.1039/c9cc02734c [Epub 2019 May 16]

abstract URL

Hürtgen, D.*, Härtel, T.*, Murray, S.M., Sourjik, V., Schwille, P.
(* contributed equally)
Functional Modules of Minimal Cell Division for Synthetic Biology
Adv Biosyst 3 (2019), 1800315, DOI: 10.1002/adbi.201800315 [Epub 2019 Apr 2]

abstract URL

Hürtgen, D., Vogel, S.K., Schwille, P.
Cytoskeletal and Actin-Based Polymerization Motors and Their Role in Minimal Cell Design
Adv Biosyst 3 (2019), 1800311, DOI: 10.1002/adbi.201800311 [Epub 2019 Apr 1]

abstract URL

Ramirez-Diaz, D., Merino-Salomon, A., Heymann, M., Schwille, P.
Bidirectional FtsZ filament treadmilling promotes membrane constriction via torsional stress
bioRxiv (2019), DOI: 10.1101/587790 [Epub 2019 Mar 24]

abstract URL

Stehr, F.*, Stein, J.*, Schueder, F., Schwille, P., Jungmann, R.
(* contributed equally)
Flat-top TIRF illumination boosts DNA-PAINT imaging and quantification
Nat Commun (2019)10:1268, DOI: 10.1038/s41467-019-09064-6 [Epub 2019 Mar 20]

abstract URL

Wade, O.K., Woehrstein, J.B., Nickels, P.C., Strauss, S., Stehr, F., Stein, J., Schueder, F., Strauss, M.T., Ganji, M., Schnitzbauer, J., Grabmayr, H., Yin, P., Schwille, P., Jungmann, R.
124-Color Super-resolution Imaging by Engineering DNA-PAINT Blinking Kinetics
Nano Lett 19 (2019), 2641-2646, DOI: 10.1021/acs.nanolett.9b00508 [Epub 2019 Mar 13]

abstract URL

Kol, M., Williams, B., Toombs-Ruane, H., Franquelim, H.G., Korneev, S., Schroeer, C., Schwille, P., Trauner, D., Holthuis, J.C.M., Frank, J.A.
Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides
eLIFE (2019);8:e43230, DOI: 10.7554/eLife.43230 [Epub 2019 Feb 5]

abstract URL

Ganzinger, K.A., Schwille, P.
More from less - bottom-up reconstitution of cell biology
J Cell Sci 132 (2019) jcs227488, DOI: 10.1242/jcs.227488 [Epub 2019 Feb 4]

abstract URL

Kai, L., Schwille, P.
Cell‐Free Protein Synthesis and Its Perspectives for Assembling Cells from the Bottom‐Up
Adv Biosyst 3 (2019) 1800322, DOI: 10.1002/adbi.201800322 [Epub 2019 Feb 4]

abstract URL

2018

Frey, E., Halatek, J., Kretschmer, S., Schwille, P.
in Physics of Biological Membranes, P. Bassereau and P. Sens, Editors. 2018, Springer International Publishing: Cham. p. 229-260

abstract URL

Kempter, S., Khmelinskaia, A., Strauss, M.T., Schwille, P., Jungmann, R., Liedl, T., Bae, W.
Single Particle Tracking and Super-Resolution Imaging of Membrane-Assisted Stop-and-Go Diffusion and Lattice Assembly of DNA Origami
ACS Nano 13 (2018) 996-1002, DOI: 10.1021/acsnano.8b04631 [Epub 2018 Dec 27]

abstract URL

Glock, P., Ramm, B., Heermann, T., Kretschmer, S., Schweizer, J., Mücksch, J., Alagöz, G., Schwille, P.
Stationary patterns in a two-protein reaction-diffusion system
ACS Synth Biol 8 (2018) 148-157, DOI: 10.1021/acssynbio.8b00415 [Epub 2018 Dec 20]

abstract URL

Sonal, Ganzinger, K.A., Vogel, S.K., Mücksch, J., Blumhardt, P., Schwille, P.
Myosin-II activity generates a dynamic steady state with continuous actin turnover in a minimal actin cortex
J Cell Sci (2019) Dec 11, 132, DOI: 10.1242/jcs.219899 [Epub 2018 Dec 11]

abstract URL

Blumhardt, P., Stein, J., Mücksch, J., Stehr, F., Bauer, J., Jungmann, R., Schwille, P.
Photo-Induced Depletion of Binding Sites in DNA-PAINT Microscopy
Molecules 23 (2018) 3165, DOI: 10.3390/molecules23123165 [Epub 2018 Nov 30]

abstract URL

Ye, W., Celiksoy, S., Jakab, A., Khmelinskaia, A., Heermann, T., Raso, A., Wegner, S.V., Rivas, G., Schwille, P., Ahijado-Guzmán, R., Sönnichsen, C.
Plasmonic Nanosensors Reveal a Height Dependence of MinDE Protein Oscillations on Membrane Features
J Am Chem Soc 140 (2018) 17901-17906, DOI: 10.1021/jacs.8b07759 [Epub 2018 Nov 27]

abstract URL

Ramm, B., Schwille, P.
In vitro reconstitution of the bacterial cytoskeleton: expected and unexpected new insights
Microb Biotechnol 12 (2019) 74-76, DOI: 10.1111/1751-7915.13336 [Epub 2018 Nov 08]

abstract URL

Wang, Q., Taschner, M., Ganzinger, K.A., Kelley, C., Villasenor, A., Heymann, M., Schwille, P., Lorentzen, E., Mizuno, N.
Membrane association and remodeling by intraflagellar transport protein IFT172
Nat Commun (2018) 9, 4684, DOI: 10.1038/s41467-018-07037-9 [Epub 2018 Nov 08]

abstract URL

Glock, P., Schwille, P.
Switching protein patterns on membranes
Curr Opin Colloid Interface Sci 38 (2018) 100-107, DOI: 10.1016/j.cocis.2018.10.004 [Epub 2018 Oct 11]

abstract URL

Jia, H., Kai, L., Heymann, M., García-Soriano, D.A., Härtel, T., Schwille, P.
Light-Induced Printing of Protein Structures on Membranes in Vitro
Nano Lett 18 (2018) 7133-7140, DOI: 10.1021/acs.nanolett.8b03187 [Epub 2018 Oct 8]

abstract URL

Litschel, T., Ramm, B., Maas, R., Heymann, M., Schwille, P.
Beating vesicles: Encapsulated protein oscillations cause dynamic membrane deformations
Angew Chem Int Ed Engl 57 (2018) 16286-16290, DOI: 10.1002/anie.201808750 [Epub 2018 Sept 30]

abstract URL

Ramm, B., Glock, P., Mücksch, J., Blumhardt, P., García-Soriano, D.A., Heymann, M., Schwille, P.
The MinDE system is a generic spatial cue for membrane protein distribution in vitro
Nat Comm 9 (2018) 3942, DOI: 10.1038/s41467-018-06310-1 [Epub 2018 Sept 26]

abstract URL

Khmelinskaia, A., Mücksch, J., Petrov, E.P., Franquelim, H.G., Schwille, P.
Control of membrane binding and diffusion of cholesteryl-modified DNA origami nanostructures by DNA spacers
Langmuir 34 (2018) 14921-14931, DOI: 10.1021/acs.langmuir.8b01850 [Epub 2018 Sept 25]

abstract URL

Rideau, E., Dimova, R., Schwille, P., Wurm, F.R., Landfester, K.
Liposomes and polymersomes: a comparative review towards cell mimicking
Chem Soc Rev 47 (2018) 8572-8610, DOI: 10.1039/C8CS00162F [Epub 2018 Sept 4]

abstract URL

Ramm, B.*, Glock, P.*, Schwille P.
(* contributed equally)
In Vitro Reconstitution of Self-Organizing Protein Patterns on Supported Lipid Bilayers
J Vis Exp 137 (2018) e58139, doi:10.3791/58139 [Epub 2018 Jul 29]

abstract URL

Niederauer, C., Blumhardt, P., Mücksch, J., Heymann, M., Lambacher, A., Schwille, P.
Direct characterization of the evanescent field in objective-type total internal reflection fluorescence microscopy
Optics Express 26 (2018) 20492-20506 [Epub 2018 Jul 28]

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Litschel, T., Ganzinger, K.A., Movinkel, T., Heymann, M., Robinson, T., Mutschler, H., Schwille P.
Freeze-thaw cycles induce content exchange between cell-sized lipid vesicles
New J Phys (2018) May 18 [Epub ahead of print]

abstract URL

Ramirez-Diaz, D.A.*, García-Soriano, D.A.*, Raso, A.*, Mücksch, J., Feingold, M., Rivas, G., Schwille P.
(* contributed equally)
Treadmilling analysis reveals new insights into dynamic FtsZ ring architecture
PLoS Biol (2018) May 18;16(5):e2004845, doi: 10.1371/journal.pbio.2004845 [Epub 2018 May 18]

abstract URL

Schwille, P., Spatz, J., Landfester, K., Bodenschatz, E., Herminghaus, S., Sourjik, V., Erb, T., Bastiaens, P., Lipowsky, R., Hyman, A., Dabrock, P., Baret, J.C., Vidakovic-Koch, T., Bieling, P., Dimova, R., Mutschler, H., Robinson, T., Tang, D., Wegner, S., Sundmacher, K.
MaxSynBio - Avenues towards creating cells from the bottom up
Angew Chem Int Ed Engl 57 (2018) 13382-13392 [Epub 2018 May 11]

abstract URL

Steiert, F., Petrov, E.P., Schultz, P., Schwille, P., Weidemann, T.
Photophysical Behavior of mNeonGreen, an Evolutionarily Distant Green Fluorescent Protein
Biophys J 114 (2018) 2419-2431 [Epub 2018 Apr 26]

abstract URL

Mücksch, J.*, Blumhardt, P.*, Strauss, M.T., Petrov, E.P., Jungmann, R., Schwille, P.
(* contributed equally)
Quantifying reversible surface binding via surface-integrated FCS
Nano Lett 18 (2018) 3185-3192 [Epub 2018 Apr 17]

abstract URL

Denk, J.*, Kretschmer, S.*, Halatek, J.*, Hartl, C., Schwille, P., Frey, E.
(* contributed equally)
MinE conformational switching confers robustness on self-organized Min protein patterns
Proc Natl Acad Sci USA 115 (2018) 4553-4558 [Epub 2018 Apr 16]

abstract URL

Kretschmer, S., Harrington, L., Schwille P.
Reverse and forward engineering of protein pattern formation
Phil Trans B (2018) 373, doi: 10.1098/rstb.2017.0104 [Epub 2018 Apr 09]

abstract URL

Khmelinskaia, A.*, Mücksch, J.*, Conci, F., Chwastek, G., Schwille P.
(* contributed equally)
FCS Analysis of Protein Mobility on Lipid Monolayers
Biophys J 114 (2018) 2444-2454 [Epub 2018 Mar 29]

abstract URL

Schwille, P.
There and back again: from the origin of life to single molecules
European Biophysics Journal 47 (2018) 493-498 [Epub 2018 Mar 22]

abstract URL

Franquelim, H.G., Khmelinskaia, A., Sobczak, J.P., Dietz, H., Schwille, P.
Membrane sculpting by curved DNA origami scaffolds
Nature Comm 9 (2018) 811 [Epub 2018 Feb 23]

abstract URL

2017

Glock, P., Broichhagen, J., Kretschmer, S., Blumhardt, P., Mücksch, J., Trauner, D., Schwille, P.
Optical control of a biological reaction-diffusion system
Angew Chem Int Ed Engl 57 (2018) 2362-2366 [Epub 2017 Dec 21]

abstract URL

Miyagi, A.*, Ramm, B.*, Schwille, P., Scheuring, S.
(* contributed equally)
High-speed AFM reveals the inner workings of the MinDE protein oscillator
Nano Lett 18 (2018) 288-296 [Epub 2017 Dec 6]

abstract URL

Schwille, P.
Biology and the art of abstraction
Biophys Rev 9 (2017) 273–275 [Epub 2017 July 29]

abstract URL

Jia, H., Heymann, M., Bernhard, F., Schwille, P., Kai, L.
Cell-free protein synthesis in micro compartments: building a minimal cell from biobricks
N Biotechnol 39 (2017) 199-205 [Epub 2017 July 06]

abstract URL

Schwille, P.
How Simple Could Life Be?
Angew Chem Int Ed Engl 56 (2017) 10998–11002 [Epub 2017 July 05]

abstract URL

Franquelim, H.G., Schwille, P.
Revolving around constriction by ESCRT-III
Nat Cell Biol 19 (2017) 754-756 [Epub 2017 June 29]

abstract URL

Kretschmer, S., Zieske, K., Schwille, P.
Large-scale modulation of reconstituted Min protein patterns and gradients by defined mutations in MinE’s membrane targeting sequence
PLoS ONE 12 (2017) e0179582 [Epub 2017 June 16]

abstract URL

Loose, M., Zieske, K., Schwille, P.
Reconstitution of Protein Dynamics Involved in Bacterial Cell Division
Subcell Biochem 84 (2017) 419-444 [Epub 2017 May 13]

abstract URL

Vogel, S.K., Greiss, F., Khmelinskaia, A., Schwille, P.
Control of lipid domain organization by a biomimetic contractile actomyosin cortex
eLife 2017;6:e24350 [Epub 2017 May 2nd]

abstract URL

2016

Worch, R., Petrasek, Z., Schwille, P., Weidemann, T.
Diffusion of Single-Pass Transmembrane Receptors: From the Plasma Membrane into Giant Liposomes
J Membr Biol 250 (2017) 393-406 [Epub 2016 Nov 8]

abstract URL

Grover, R., Fischer, J., Schwarz, F.W., Walter, W.J., Schwille, P., Diez, S.
Transport efficiency of membrane-anchored kinesin-1 motors depends on motor density and diffusivity
Proc Nat Acad Sci USA 113 (2016) E7185-E7193 [Epub 2016 Nov 1]

abstract URL

Visco, I., Hoege, C., Hyman, A.A., Schwille, P.
In vitro reconstitution of a membrane switch mechanism for the polarity protein LGL
J Mol Biol 428 (2016) 4828-4842 [Epub 2016 Oct 6]

abstract URL

Frank, J.A., Franquelim, H.G., Schwille, P., Trauner, D.
Optical Control of Lipid Rafts with Photoswitchable Ceramides
J Am Chem Soc 138 (2016) 12981-12986 [Epub 2016 Sept 14]

abstract URL

Pylypenko, O., Welz, T., Tittel, J., Kollmar, M., Chardon, F., Malherbe, G., Weiss, S., Michel, C.I.L., Samol-Wolf, A., Grasskamp, A.T., Hume, A., Goud, B., Baron, B., England, P., Titus, M.A., Schwille, P., Weidemann, T., Houdusse, A., Kerkhoff, E. .
Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes
eLife 2016;5:e17523 [Epub 2016 Sept 13]

abstract URL

Zieske, K., Chwastek,G., Schwille, P.
Protein Patterns and Oscillations on Lipid Monolayers and in Microdroplets
Angew Chem Int Ed Engl 55 (2016) 13455-13459 [Epub 2016 Jul 28]

abstract URL

Lambertz, C., Martos, A., Henkel, A., Neiser, A., Kliesch, T.T., Janshoff, A., Schwille, P., Sönnichsen, C.
Single Particle Plasmon Sensors as Label-free Technique to Monitor MinDE Protein Wave Propagation on Membranes
Nano Letters 16 (2016) 3540-3544 [Epub 2016 May 12]

abstract URL

Czogalla, A., Franquelim, H.G., Schwille, P.
DNA Nanostructures on Membranes as Tools for Synthetic Biology
Biophysical Journal 110 (2016) 1698-1707 [Epub 2016 Apr 26]

abstract URL

Khmelinskaia, A., Franquelim, H.G., Petrov, E., Schwille, P.
Effect of anchor positioning on binding and diffusion of elongated 3D DNA nanostructures on lipid membranes
Journal of Physics D - Applied Physics 49 (2016) 194001 [Epub 2016 Apr 13]

abstract URL

Kretschmer, S., Schwille, P.
Pattern formation on membranes and its role in bacterial cell division
Current Opinion in Cell Biology 38 (2016) 52-59 [Epub 2016 Feb 23]

abstract URL

Herold, C., Schwille, P., Petrov, E.
Single DNA molecules on freestanding and supported cationic lipid bilayers: diverse conformational dynamics controlled by the local bilayer properties
Journal of Physics D - Applied Physics 49 (2016) 074001 [Epub 2016 Jan 15]

abstract URL
2011 - 2015


2015

Thomas, F.A., Visco, I., Petrášek, Z., Heinemann, F., Schwille, P.
Diffusion coefficients and dissociation constants of enhanced green fluorescent protein binding to free standing membranes
Data in brief 5 (2015) 537-541 [Epub 2015 Oct 26]

abstract URL

Thomas, F.A., Visco, I., Petrášek, Z., Heinemann, F., Schwille, P.
Introducing a fluorescence-based standard to quantify protein partitioning into membranes
Biochim Biophys Acta 1848 (2015) 2932-2941 [Epub 2015 Sep 2]

abstract URL

Schwille, P.
Jump-starting life? Fundamental aspects of synthetic biology
J Cell Biol 210 (2015) 687-690 [Epub 2015 Aug 31]

abstract URL

Kurgonaite, K., Gandhi, H., Kurth, T., Pautot, S., Schwille, P., Weidemann, T., Bökel, C.
Essential role of endocytosis for Interleukin-4 receptor mediated JAK/STAT signalling
J Cell Sci 128 (2015) 3781-3795 [Epub 2015 Aug 25]

abstract URL

Martos, A., Raso, A., Jimenez, M., Petrasek, Z., Rivas, G., Schwille, P.
FtsZ Polymers Tethered to the Membrane by ZipA Are Susceptible to Spatial Regulation by Min Waves
Biophys J 108 (2015) 2371-2383 [Epub 2015 May 5]

abstract URL

Sezgin, E., Gutmann, T., Buhl, T., Dirkx, R., Grzybek, M., Coskun, Ü., Solimena, M., Simons, K., Levental, I., Schwille, P.
Adaptive lipid packing and bioactivity in membrane domains
PLoS One 2015;10(4):e0123930 [Epub 2015 Apr 23]

abstract URL

Czogalla, A., Kauert, D.J., Franquelim, H.G., Uzunova, V., Zhang, Y., Seidel, R., Schwille, P.
Amphipathic DNA Origami Nanoparticles to Scaffold and Deform Lipid Membrane Vesicles
Angew Chem Int Ed Engl 54 (2015) 6501-6505 [Epub 2015 Apr 16]

abstract URL

Petrasek, Z., Schwille, P.
Simple membrane-based model of the Min oscillator
New J Phys 17 (2015) 043023 [Epub 2015 Apr 14]

abstract URL

Zieske, K., Schwille, P.
Reconstituting geometry-modulated protein patterns in membrane compartments
Methods Cell Biol 128 (2015) 149-163 [Epub 2015 Apr 8]

abstract URL

Kretschmer, S., Schwille, P.
Rekonstitution biologischer Selbstorganisation in vitro
BIOspektrum 21 (2015) 148-150 [Epub 2015 Mar 30]

abstract URL

Arumugam, S., Petrov, E.P., Schwille, P.
Cytoskeletal Pinning Controls Phase Separation in Multicomponent Lipid Membranes
Biophys J 108 (2015) 1104-1113 [Epub 2015 Mar 10]

abstract URL

Tittel, J., Welz, T., Czogalla, A., Dietrich, S., Samol-Wolf, A., Schulte, M., Schwille, P., Weidemann, T., Kerkhoff, E.
Membrane Targeting of the Spir-formin Actin Nucleator Complex Requires a Sequential Handshake of Polar Interactions
J Biol Chem 290 (2015) 6428-6444 [Epub 2015 Jan 06]

abstract URL

 

2014

Kretschmer, S., Schwille, P.
Toward Spatially Regulated Division of Protocells: Insights into the E. coli Min System from in Vitro Studies
Life (Basel) 4 (2014) 915-928 [Epub 2014 Dec 11]

abstract URL

Czogalla, A., Kauert, D.J., Seidel, R., Schwille, P., Petrov, E.P.
DNA Origami Nanoneedles on Freestanding Lipid Membranes as a Tool To Observe Isotropic-Nematic Transition in Two Dimensions
Nano Lett. 5 (2015) 649-655 [Epub 2014 Dec 05]

abstract URL

Gandhi, H., Remigiusz, W., Kurgonaite, K., Hintersteiner, M., Schwille, P., Bökel, C., Weidemann, T.
Dynamics and Interaction of Interleukin-4 Receptor Subunits in Living Cells
Biophysical Journal 107 (2014) 2515-2527

abstract URL

Zieske, K., Schwille, P.
Reconstitution of self-organizing protein gradients as spatial cues in cell-free systems
eLife 2014;10.7554/eLife.03949 [Epub 2014 Oct 1]

abstract URL

Weidemann, T., Mücksch, J., Schwille, P.
Fluorescence fluctuation microscopy: a diversified arsenal of methods to investigate molecular dynamics inside cells
Curr Opin Struct Biol 28 (2014) 69-76 [Epub 2014 Aug 12]

abstract URL

Rivas, G., Vogel, S.K., Schwille, P.
Reconstitution of cytoskeletal protein assemblies for large-scale membrane transformation
Curr Opin Chem Biol 22 (2014) 18-26 [Epub 2014 Aug 11]

abstract URL

Bacia, K., Haustein, E., Schwille, P.
Fluorescence correlation spectroscopy: principles and applications
Cold Spring Harb Protoc 7 (2014) 709-725 doi:10.1101/pdb.top081802 [Epub 2014 Jul 1]

abstract URL

Zieske, K., Schweizer, J., Schwille, P.
Surface topology assisted alignment of Min protein waves
FEBS Lett 588 (2014) 2545-2549 [Epub 2014 Jun 14]

abstract URL

Härtel, T., Schwille, P.
ESCRT-III mediated cell division in Sulfolobus acidocaldarius - a reconstitution perspective
Front Microbiol (2014) Jun 4;5:257 [Epub 2014 Jun 4]

abstract URL

Visco, I., Chiantia, S., Schwille, P.
Asymmetric supported lipid bilayer formation via methyl-β-cyclodextrin mediated lipid exchange: influence of asymmetry on lipid dynamics and phase behavior
Langmuir 30 (2014) 7475-7484 [Epub 2014 Jun 2]

abstract URL

Müller, P., Schwille, P., Weidemann, T.
PyCorrFit - generic data evaluation for fluorescence correlation spectroscopy
Bioinformatics 30 (2014) 2532-2533 [Epub 2014 May 13]

abstract URL

Arumugam, S., Petrasek, Z., Schwille, P.
MinCDE exploits the dynamic nature of FtsZ filaments for its spatial regulation
Proc Nat Acad Sci USA 111 (2014) E1192-1200 [Epub 2014 Mar 18]

abstract URL

Petrasek, Z., Wiedemann, J., Schwille, P.
Towards a spectrum-based bar code for identification of weakly fluorescent microparticles
Methods Appl Fluoresc 2 (2014) 015004 [Epub 2014 Feb 24]

abstract URL

Schwille, P.
Bacterial Cell Division: A Swirling Ring to Rule Them All?
Curr Biol 24 (2014) R157-R159 [Epub 2014 Feb 17]

abstract URL

Reichert, A.S., Schwille, P.
Highlight issue: Membranes in Motion
Biol Chem 395 (2014) 251-251 [Epub 2014 Jan 15]

abstract URL

Müller, P., Schwille, P., Weidemann, T.
Scanning Fluorescence Correlation Spectroscopy (SFCS) with a Scan Path Perpendicular to the Membrane Plane
Methods Mol Biol 1076 (2014) 635-651 [Epub 2013 Oct 14]

abstract URL

 

2013

Ehrlich, H., Rigby, J.K., Botting, J.P., Tsurkan, M.V., Werner, C., Schwille, P., Petrasek, Z., Pisera, A., Simon, P., Sivkov, V.N., Vyalikh, D.V., Molodtsov, S.L., Kurek, D., Kammer, M., Hunoldt, S., Born, R., Stawski, D., Steinhof, A., Bazhenov, V.V., Geisler, T.
Discovery of 505-million-year old chitin in the basal demosponge Vauxia gracilenta
Scientific Reports 3 (2013) ArtNo. 3497 [Epub 2013 Dec 13]

abstract URL

Bisicchia, P., Arumugam, S., Schwille, P., Sherratt, D.
MinC, MinD, and MinE Drive Counter-oscillation of Early-Cell-Division Proteins Prior to Escherichia coli Septum Formation
MBio 4 (2013) e00856-13 [Epub 2013 Dec 10]

abstract URL

Bonny, M., Fischer-Friedrich, E., Loose, M., Schwille, P., Kruse, K.
Membrane Binding of MinE Allows for a Comprehensive Description of Min-Protein Pattern Formation
PLoS Comput Biol 9 (2013) e1003347 [Epub 2013 Dec 5]

abstract URL

Gaitzsch, J., Voit, B., Schwille, P., Appelhans, D., Janke, A., Strempel, M.
Cross-linked and pH Sensitive Supported Polymer Bilayers from Polymersomes – Studies Concerning Thickness, Rigidity and Fluidity
Soft Matter 10 (2014) 75-82 [Epub 2013 Oct 10]

abstract URL

Martos, A., Petrasek, Z., Schwille, P.
Propagation of MinCDE waves on free-standing membranes
Environ Microbiol 15 (2013) 3319-3326 [Epub 2013 Oct 7]

abstract URL

Vogel, S.K., Heinemann, F., Chwastek, G., Schwille, P.
The design of MACs (Minimal Actin Cortices)
Cytoskeleton (Hoboken) 70 (2013) 706-717 [Epub 2013 Aug 28]

abstract URL

Özhan, G., Sezgin, E., Wehner, D., Pfister, A.S., Kühl, S.J., Kagermeier-Schenk, B., Kühl, M., Schwille, P., Weidinger, G.
Lypd6 Enhances Wnt/β-Catenin Signaling by Promoting Lrp6 Phosphorylation in Raft Plasma Membrane Domains
Dev Cell 26 (2013) 331-345 [Epub 2013 Aug 26]

abstract URL

Keller, H., Worch, R., Schwille, P.
Model membrane systems
Methods Mol Biol 1008 (2013) 417-438 [Epub 2013 Jun 09]

abstract URL

Klamp, T., Camps, M., Nieto, B., Guasch, F., Ranasinghe, R.T., Wiedemann, J., Petrasek, Z., Schwille, P., Klenerman, D., Sauer, M.
Highly Rapid Amplification-Free and Quantitative DNA Imaging Assay
Sci Rep 3 (2013) 1852 [Epub 2013 May 16]

abstract URL

Chwastek, G., Schwille, P.
A Monolayer Assay Tailored to Investigate Lipid-Protein Systems
ChemPhysChem 14 (2013) 1877-1881 [Epub 2013 Apr 18]

abstract URL

Heinemann, F., Vogel, S.K., Schwille, P.
Lateral Membrane Diffusion Modulated by a Minimal Actin Cortex
Biophys J 104 (2013) 1465-1475 [Epub 2013 Apr 2]

abstract URL

Sezgin, E., Chwastek, G., Aydogan, G., Levental, I., Simons, K., Schwille, P.
Photoconversion of Bodipy-Labeled Lipid Analogues
ChemBioChem 14 (2013) 695-698 [Epub 2013 Mar 19]

abstract URL

Kotlarz, D., Ziętara, N., Uzel, G., Weidemann, T., Braun, C.J., Diestelhorst, J., Krawitz, P.M., Robinson, P.N., Hecht, J., Puchałka, J., Gertz, E.M., Schäffer, A.A., Lawrence, M.G., Kardava, L., Pfeifer, D., Baumann, U., Pfister, E.-D., Hanson, E.P., Schambach, A., Jacobs, R., Kreipe, H., Moir, S., Milner, J.D., Schwille, P., Mundlos, S., Klein, C.
Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome
J Exp Med 210 (2013) 433-443 [Epub 2013 Feb 25]

abstract URL

Sahoo, H., Schwille, P.
Influence of glycosaminoglycans on lipid dynamics in supported phospholipid bilayers
Soft Matter 9 (2013) 3859-3865 [Epub 2013 Feb 25]

abstract URL

Schwille, P.
Chemistry Needed: Synthetic Biology as a New Incentive for Interdisciplinarity
Angew Chem Int Ed 52 (2013) 2616-2617 [Epub 2013 Feb 20]

abstract URL

Yu, J.H., Kwon, S.H., Petrášek, Z., Park, O.K., Jun, S.W., Shin, K., Choi, M., Park, Y.I., Park, K., Na, H.B., Lee, N., Lee, D.W., Kim, J.H., Schwille, P., Hyeon, T.
High-resolution three-photon biomedical imaging using doped ZnS nanocrystals
Nat Mater 12 (2013) 359-366 [Epub 2013 Feb 17]

abstract URL

Jalmar, O., François-Moutal, L., García-Sáez, A.J., Perry, M., Granjon, T., Gonzalvez, F., Gottlieb, E., Ayala-Sanmartin, J., Klösgen, B., Schwille, P., Petit, P.X.
Caspase-8 binding to cardiolipin in giant unilamellar vesicles provides a functional docking platform for bid
PLoS One 2013;8(2):e55250 [Epub 2013 Feb 13]

abstract URL

Tüngler, V., Staroske, W., Kind, B., Dobrick, M., Kretschmer, S., Schmidt, F., Krug, C., Lorenz, M., Chara, O., Schwille, P., Lee-Kirsch, M.A.
Single-stranded nucleic acids promote SAMHD1 complex formation
J Mol Med (Berl). 91 (2013) 759-770 [Epub 2013 Jan 31]

abstract URL

Vogel, S.K., Petrasek, Z., Heinemann, F., Schwille, P.
Myosin motors fragment and compact membrane-bound actin filaments
eLife 2013;2:e00116. [Epub 2013 Jan 8]

abstract URL

Betaneli, V., Schwille, P.
Fluorescence correlation spectroscopy to examine protein-lipid interactions in membranes
Methods Mol Biol 974 (2013) 253-278

abstract URL

Weidemann, T., Schwille, P.
Dual-color fluorescence cross-correlation spectroscopy with continuous laser excitation in a confocal setup
Methods Enzymol 518 (2013) 43-70

abstract URL

Zieske, K., Schwille, P.
Reconstitution of Pole-to-Pole Oscillations of Min Proteins in Microengineered Polydimethylsiloxane Compartments
Angew Chem Int Ed Engl. 52 (2013) 459-462 [Epub 2012 Nov 26]

abstract URL

Keller, H., Kräusslich, H.G., Schwille, P.
Multimerizable HIV Gag derivative binds to the liquid-disordered phase in model membranes
Cell Microbiol 15 (2013) 237-247 [Epub 2012 Dec 12]

abstract URL

Czogalla, A., Petrov, E.P., Kauert, D.J., Uzunova, V., Zhang, Y., Seidel, R., Schwille, P.
Switchable domain partitioning and diffusion of DNA origami rods on membranes
Faraday Discuss 161 (2013) 31-43 [Epub 2012 Oct 8]

abstract URL

 

2012

Molnar, E., Swamy, M., Holzer, M., Beck-Garcia, K., Worch, R., Thiele, C., Guigas, G., Boye, K., Luescher, I.F., Schwille, P., Schubert, R., Schamel, W.W.
Cholesterol and sphingomyelin drive ligand-independent T-cell antigen receptor nanoclustering
J Biol Chem 287 (2012) 42664-42674 [Epub 2012 Oct 22]

abstract URL

Martos, A., Jiménez, M., Rivas, G., Schwille, P.
Towards a bottom-up reconstitution of bacterial cell division
Trends Cell Biol 22 (2012) 634-643 [Epub 2012 Oct 12]

abstract URL

Schweizer, J., Loose, M., Bonny, M., Kruse, K., Mönch, I. Schwille, P.
Geometry sensing by self-organized protein patterns Proc Natl Acad Sci USA 109 (2012) 15283-15288

abstract URL

Arumugam, S., Chwastek, G., Fischer-Freidrich, E., Ehrig, C., Mönch, I. Schwille, P.
Surface Topology Engineering of Membranes for the Mechanical Investigation of the Tubulin Homologue FtsZ
Angew Chem Int Ed Engl 51 (2012) 11858-11862

abstract URL

Saenz, J.P., Sezgin, E., Schwille, P., Simons, K.
Functional convergence of hopanoids and sterols in membrane ordering
Proc Natl Acad Sci USA 109 (2012) 14236-14240

abstract URL

Heinemann, F., Betaneli, V., Thomas, F.A., Schwille, P.
Quantifying lipid diffusion by fluorescence correlation br/ectroscopy - a critical treatise Langmuir 28 (2012) 13395-13404

abstract URL

Sezgin, E., Schwille, P.
Model membrane platforms to study protein-membrane interactions
Mol Membr Biol 29 (2012) 144-154 [Epub 2012 Jul 26]

abstract URL

Betaneli, V., Worch, R., Schwille, P.
Effect of temperature on the formation of liquid phase-separating giant unilamellar vesicles (GUV)
Chem Phys Lipids 165 (2012) 630-637

abstract URL

Petrov, E.P., Petrosyan, R., Schwille, P.
Translational and rotational diffusion of micrometer-sized solid domains in lipid membranes
Soft Matter 8 (2012) 7552-7555

abstract URL

Sezgin, E., Kaiser, HJ., Baumgart, T., Schwille, P., Simons, K., Levental, I.
Elucidating membrane structure and protein behavior using giant plasma membrane vesicles
Nature Protocols 7 (2012) 1042-1051

abstract URL

Vogel, SK., Schwille, P.
Minimal systems to study membrane-cytoskeleton interactions.
Curr Opin Biotechnol 23 (2012) 758-765

abstract URL

Sezgin, E., Levental, I., Grzybek, M., Schwarzmann, G., Mueller, V., Honigmann, A., Belov, VN., Eggeling, C., Coskun, U., Simons, K., Schwille, P.
Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes
Biochim Biophys Acta 1818(7) (2012) 1777-84

abstract URL

Herold, C., Chwastek, G., Schwille, P., Petrov, EP.
Efficient Electroformation of Supergiant Unilamellar Vesicles Containing Cationic Lipids on ITO-Coated Electrodes
Langmuir 28(13) (2012) 5518-21

abstract URL

Ries, J., Schwille, P.
Fluorescence correlation spectroscopy
Bioessays 34(5) (2012) 361-368

abstract URL

Mütze, J., Iyer, V., Macklin, J., Colonell, J., Karsh, B., Petrasek, Z., Schwille, P., Looger, L., Lavis, L., Harris, T.
Excitation Spectra and Brightness Optimization of Two-Photon Excited Probes
Biophys J 102(4) (2012) 934-944

abstract URL

Bacia, K., Petrasek, Z., Schwille, P.
Correcting for Spectral Cross-Talk in Dual-Color Fluorescence Cross-Correlation Spectroscopy.
Chemphyschem 13(5) (2012) 1221-1231

abstract URL

Herold, C., Leduc, C., Stock, R., Diez, S., Schwille, P.
Long-Range Transport of Giant Vesicles along Microtubule Networks.
Chemphyschem 13(4) (2012) 1001-1006

abstract URL

Betaneli, V., Petrov, EP., Schwille, P.
The Role of Lipids in VDAC Oligomerization
Biophys J 102(3) (2012) 523-31

abstract URL

Dubavik, A., Sezgin, E., Lesnyak, V., Gaponik, N., Schwille, P., Eychmuller, A.
Penetration of Amphiphilic Quantum Dots through Model and Cellular Plasma Membranes
ACS Nano 6(3) (2012) 2150-2156

abstract URL

Ohrt, T., Mütze, J., Svoboda, P., Schwille, P.
Intracellular localization and routing of miRNA and RNAi pathway components
Curr Top Med Chem 12(2) (2012) 79-88

abstract URL

Schweizer, J., Schwille, P.
Synthetic biology: a new access to our understanding of biological phenomena
Bioforum 35(1) (2012) 25-27

abstract URL

Schwille, P.
Biological self-organization in the test tube - a way to artificial cells?
Nova Acta Leopold 116(394) (2012) 119-130

abstract  

Schwille, P.
Biological self-organization in a test tube - a process for an artificial cell?
Naturwiss Rundsch 65(8) (2012) 393-398

abstract  

 

2011

Petrasek, Z., Derenko, S., Schwille, P.
Circular scanning fluorescence correlation spectroscopy on membranes.
Opt Express 19(25) (2011) 25006-21

abstract URL

Weidemann, T., Worch, R., Kurgonaite, K., Hintersteiner, M., Bökel, C., Schwille, P.
Single Cell Analysis of Ligand Binding and Complex Formation of Interleukin-4 Receptor Subunits
Biophys J 101(10) (2011) 2360-9

abstract URL

Schwille, P.
Bottom-up synthetic biology: engineering in a tinkerer's world.
Science 333(6047) (2011) 1252-4

abstract Free
access!

Garcia-Saez, A., Buschhorn, S., Keller, H., Anderluh, G., Simons, K. & Schwille, P.
Oligomerization and pore formation by Equinatoxin II inhibit endocytosis and lead to plasma membrane reorganization.
J Biol Chem 286(43) (2011) 37768-77

abstract URL

Heinemann, F. & Schwille, P.
Preparation of Micrometer-Sized Free-Standing Membranes.
Chemphyschem 12(14) (2011) 2568-71

abstract URL

Arumugam, S., Chwastek, G. & Schwille, P.
Protein-membrane interactions: the virtue of minimal systems in systems biology.
Wiley Interdiscip Rev Syst Biol Med 3(3) (2011) 269-280

abstract URL

Boldajipour, B., Doitsidou, M., Tarbashevich, K., Laguri, C., Yu, S.R., Ries, J., Dumstrei, K., Thelen, S., Dörries, J., Messerschmidt, E.M., Thelen, M., Schwille, P., Brand, M., Lortat-Jacob, H. & Raz, E.
Cxcl12 evolution - subfunctionalization of a ligand through altered interaction with the chemokine receptor.
Development (2011) 138 2909-2914

abstract URL

Ohrt, T., Staroske, W., Mütze, J., Crell, K., Landthaler, M. & Schwille, P.
Fluorescence cross-correlation spectroscopy reveals mechanistic insights on the effect of 2’-O-methyl modified siRNAs in living cells.
Biophys J (2011) 100(12) 2981-2990

abstract URL

Sezgin, E. & Schwille, P.
Fluorescence Techniques to Study Lipid Dynamics.
Cold Spring Harb Perspect Biol. (2011) 3(11)

abstract URL

Loose, M., Kruse, K. & Schwille, P.
Protein self-organization: lessons from the min system.
Annu Rev Biophys (2011) 40 315-336

abstract URL

Ehrig, J., Petrov, E.P. & Schwille, P.
Phase separation and near-critical fluctuations in two-component lipid membranes: Monte Carlo simulations on experimentally relevant scales.
New J Phys (2011) 13(4) (2011) 045019

abstract URL

Loose, M., Fischer-Friedrich, E., Herold, C., Kruse, K. & Schwille, P.
Min protein patterns emerge from rapid rebinding and membrane interaction of MinE.
Nat Struct Mol Biol (2011) 18 577-583

abstract URL

Sahoo, H. & Schwille, P.
FRET and FCS - Friends or Foes?
ChemPhysChem (2011) 12(3) 532-541

abstract URL

Gaitzsch, J., Appelhans, D., Gräfe, D., Schwille, P. & Voit, B.
Photo-crosslinked and pH sensitive polymersomes for triggering the loading and release of cargo.
Chem Commun (2011) 47 3466-3468

abstract URL

Franquelim, H.G., Chiantia, S., Veiga, A.S., Santos, N.C., Schwille, P. & Castanho M.A.
Anti-HIV-1 antibodies 2F5 and 4E10 interact differently with lipids to bind their epitopes.
AIDS (2011) 25(4) 419-28

abstract URL

Ehrig, J., Petrov, E.P. & Schwille, P.
Near-critical fluctuations and cytoskeleton-assisted phase separation lead to subdiffusion in cell membranes.
Biophys J 100(1) (2011) 80-9

abstract URL

Chiantia, S., Schwille, P., Klymchenko, A.S. & London E.
Asymmetric GUVs Prepared by MbCD-Mediated Lipid Exchange: An FCS Study.
Biophys J 100(1) (2011) L1-3

abstract URL

Carlotto, S., Fortunati, I., Ferrante, C., Schwille, P., Polimeno, A.
Time correlated fluorescence characterization of an asymmetrically focused flow in a microfluidic device
Microfluid Nanofluid 10 (2011) 551-561 [Epub 2010 Sep 14]

abstract URL

Mütze, J., Ohrt, T. & Schwille, P.
Fluorescence correlation spectroscopy in vivo.
Laser & Photonics Reviews 5(1) (2011) 52–67

 

2006 - 2010


2010

Kim, S.A., Sanabria, H., Digman, M.A., Gratton, E., Schwille, P., Zipfel, W.R. & Waxham, M.N.
Quantifying translational mobility in neurons: comparison between current optical techniques.
J Neurosci 30(49) (2010) 16409-16

 
abstract URL

Apellaniz, B., Nieva, J.L., Schwille, P. & Garcia-Saez, A.J.
All-or-none versus graded: single-vesicle analysis reveals lipid composition effects on membrane permeabilization.
Biophys J 99(11) (2010) 3619-28

 
abstract URL

Worch, R., Bökel, C., Höfinger, S., Schwille, P. & Weidemann T.
Focus on composition and interaction potential of single-pass transmembrane domains.
Proteomics 10(23) (2010) 4196-208

 
abstract URL

Fuertes, G., Garcia-Saez, A.J., Esteban-Martin, S., Gimenez, D., Sanchez-Munoz, O.L., Schwille P., & Salgado J.
Pores formed by baxαlpha5 relax to a smaller size and keep at equilibrium.
Biophys J 99(9) (2010), 2917-25

 
abstract URL

Plochberger B., Stockner T., Chiantia S., Brameshuber M., Weghuber J., Hermetter A., Schwille P. & Schütz G.J.
Cholesterol Slows down the Lateral Mobility of an Oxidized Phospholipid in a Supported Lipid Bilayer.
Langmuir 26(22) (2010) 17322-17329

 
abstract URL

Klose, C., Ejsing, C.S., Garcia-Saez, A.J., Kaiser, H.J., Sampaio, J.L., Surma, M.A., Shevchenko, A., Schwille, P. & Simons, K.
Yeast lipids can phase separate into micrometer-scale membrane domains.
J Biol Chem 285(39) (2010) 30224-32

 
abstract URL

Petrasek, Z., Ries, J. & Schwille, P.
Scanning FCS for the Characterization of Protein Dynamics in Live Cells.
Methods Enzymol. 472C (2010) 317-343

 
abstract URL

Ries, J., Bayer, M., Csúcs, G., Dirkx, R., Solimena, M., Ewers, H. & Schwille, P.
Automated suppression of sample-related artifacts in Fluorescence Correlation Spectroscopy.
Opt. Express 18 (2010) 11073-11082

 
abstract URL

Stirnnagel, K., Luftenegger, D., Stange, A., Swiersy, A., Mullers, E., Reh, J., Stanke, N., Grosze, A., Chiantia, S., Keller, H., Schwille, P., Hanenberg, H., Zentgraf, H. & Lindemann, D.
Analysis of Prototype Foamy Virus particle-host cell interaction with autofluorescent retroviral particles.
Retrovirology 7(1) (2010) 45

 
abstract URL

Herold, C., Schwille, P. & Petrov, E. P.
DNA condensation at freestanding cationic lipid bilayers.
Phys Rev Lett 104 (2010) 148102

 
abstract URL

Apellaniz, B., García-Sáez, A.J., Huarte, N., Kunert, R., Vorauer-Uhl, K., Katinger, H., Schwille P. & Nieva, J.L.
Confocal microscopy of giant vesicles supports the absence of HIV-1 neutralizing 2F5 antibody reactivity to plasma membrane phospholipids.
FEBS Lett 584(8) (2010) 1591-1596

 
abstract URL

Ewers, H., Römer, W., Smith, A. E., Bacia, K., Dmitrieff, S., Chai, W., Mancini, R., Kartenbeck, J., Chambon, V., Berland, L., Oppenheim, A., Schwarzmann, G., Feizi, T., Schwille, P., Sens, P., Helenius, A. & Johannes, L.
GM1 structure determines SV40-induced membrane invagination and infection.
Nat Cell Biol 12 (2010) 11-8

 
abstract URL

García-Sáez, A. J., Carrer, D. C. & Schwille, P.
Fluorescence correlation spectroscopy for the study of membrane dynamics and organization in giant unilamellar vesicles.
Methods Mol Biol 606 (2010) 493-508

 
abstract URL

García-Sáez, A.J. & Schwille, P.
Stability of lipid domains.
FEBS Lett 584(9) (2010), 1653-8

 
abstract URL

Mütze, J., Ohrt, T., Petrasek, Z. & Schwille, P.
In vivo Fluorescence Correlation and Cross-Correlation Spectroscopy. In: Single Molecule Spectroscopy in Chemistry, Physics and Biology. Nobel Symposium. (Gräslund, A.; Rigler, R.; Widengren, J., eds.)
Springer (2010)

 
abstract URL

Ehrig, J. PJ., Petrov, P. & Schwille, P.
Near-critical fluctuations and cytoskeleton-assisted phase separation lead to subdiffusion in cell membranes.
arXiv.org, e-Print Arch., Phys. (2010) 1-26, arXiv:1010 1207v1011

abstract URL

Ehrig, J. PJ., Petrov, P. & Schwille, P.
Phase separation and near-critical fluctuations in two-component lipid membranes: Monte Carlo simulations on experimentally relevant scales.
arXiv.org, e-Print Arch., Phys. (2010) 1-36, arXiv:1009 4860v1001

abstract URL

Ries, J., Petrasek, Z., Garcia-Saez, A.J. & Schwille, P.
A comprehensive framework for fluorescence cross-correlation spectroscopy
New J Phys 12 (2010)

abstract URL

2009

Dasgupta, U., Bamba, T., Chiantia, S., Karim, P., Tayoun, A. N. A., Yonamine, I., Rawat, S. S., Rao, R. P., Nagashima, K., Fukusaki, E., Puri, V., Dolph, P. J., Schwille, P., Acharya, J. K. & Acharya, U.
Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction.
Proc Natl Acad Sci U S A 106(47) (2009), 20063-8

 
abstract URL

Weidemann, T. & Schwille, P.
Fluorescence Correlation Spectroscopy in Living Cells. In: Handbook of Single Molecule Biophysics. (P. Hinterdorfer and A. Van Oijen, eds.)
Springer (2009)

 
  URL

Petrov, E. P., Bläul, C. & Schwille, P.
Memory in blinking dynamics of silver nanoparticles. In: Physics, Chemistry and Application of Nanostructures. (V.E. Borisenko, V.S. Gurin and S.V. Gaponenko, eds.)
World Scientific, Singapore (2009) 172-175

 
   

Carrer, D. C., Kummer, E., Chwastek, G., Chiantia, S. & Schwille, P.
Asymmetry determines the effects of natural ceramides on model membranes.
Soft Matter 5 (2009) 3279 - 3286

 
abstract URL

Loose, M. & Schwille, P.
Biomimetic membrane systems to study cellular organization.
J Struct Biol 168 (2009) 143-151

 
abstract URL

García-Sáez, A. J., Ries, J., Orzáez, M., Pérez-Payà, E. & Schwille, P.
Membrane promotes tBID interaction with BCL(XL).
Nat Struct Mol Biol 16 (2009) 1178 - 1185

 
abstract URL

Yu, S. R., Burkhardt, M., Nowak, M., Ries, J., Petrásek, Z., Scholpp, S., Schwille, P. & Brand, M.
Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules.
Nature 461 (2009) 533-536

 
abstract URL

Ries, J., Yu, S. R., Burkhardt, M., Brand, M. & Schwille, P.
Modular scanning FCS quantifies receptor-ligand interactions in living multicellular organisms.
Nat Methods 6 (2009) 643-645

 
abstract URL

Keller, H., Lorizate, M. & Schwille, P.
PI(4,5)P(2) Degradation Promotes the Formation of Cytoskeleton-Free Model Membrane Systems.
Chemphyschem 10 (2009) 2805 - 2812

 
abstract URL

Ivashyna, O., García-Sáez, A. J., Ries, J., Christenson, E. T., Schwille, P. & Schlesinger, P. H.
Detergent-activated BAX protein is a monomer.
J Biol Chem 284 (2009) 23935-23946

 
abstract URL

García-Sáez, A. J. & Schwille, P.
Surface analysis of membrane dynamics.
Biochim Biophys Acta 1798(4) (2010), 766-76

 
abstract URL

Ries, J., Chiantia, S. & Schwille, P.
Accurate determination of membrane dynamics with line-scan FCS.
Biophys J 96 (2009) 1999-2008

 
abstract URL

Weinmann, L., Höck, J., Ivacevic, T., Ohrt, T., Mütze, J., Schwille, P., Kremmer, E., Benes, V., Urlaub, H. & Meister, G.
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.
Cell 136 (2009) 496-507

 
abstract URL

Chiantia, S., Ries, J. & Schwille, P.
Fluorescence correlation spectroscopy in membrane structure elucidation.
Biochim Biophys Acta 1788 (2009) 225-233

 
abstract URL

Schwille, P. & Diez, S.
Synthetic biology of minimal systems.
Crit Rev Biochem Mol Biol 44 (2009) 223-242

 
abstract URL

Gärtner, M., Mütze, J., Ohrt, T. & Schwille, P.
Fluorescence Lifetime Correlation Spectroscopy for precise concentration detection in vivo by background subtraction.
Proc SPIE 7368 (2009) 73681V-73681V-7

 
abstract URL

Schwille, P., Heinze, K., Dittrich P., & Haustein, E.
Two-Photon Fluorescence Correlation Spectroscopy. In: Biomedical Optical Imaging. (Fujimoto, J. G., Farkas, D., eds.)
Oxford University Press (2009)

 
abstract URL

2008

Petrásek, Z., Hoege, C., Mashaghi, A., Ohrt, T., Hyman, A. A. & Schwille, P.
Characterization of protein dynamics in asymmetric cell division by scanning fluorescence correlation spectroscopy.
Biophys J 95 (2008) 5476-5486

 
abstract URL

Ohrt, T., Mütze, J., Staroske, W., Weinmann, L., Höck, J., Crell, K., Meister, G. & Schwille, P.
Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells.
Nucleic Acids Res 36 (2008) 6439-6449

 
abstract URL

Merkle, D., Kahya, N. & Schwille, P.
Reconstitution and anchoring of cytoskeleton inside giant unilamellar vesicles.
Chembiochem 9 (2008) 2673-2681

 
abstract URL

Krishnan, M., Petrásek, Z., Mönch, I. & Schwille, P.
Electrostatic self-assembly of charged colloids and macromolecules in a fluidic nanoslit.
Small 4 (2008) 1900-1906

 
  URL

Petrásek, Z. & Schwille, P.
Fluctuations as a source of information in fluorescence microscopy.
J R Soc Interface 6 (2009) S15-S25

 
abstract URL

García-Sáez, A. J. & Schwille, P.
Fluorescence correlation spectroscopy for the study of membrane dynamics and protein/lipid interactions.
Methods 46 (2008) 116-122

 
abstract URL

Carrer, D. C., Schmidt, A. W., Knölker, H. & Schwille, P.
Membrane domain-disrupting effects of 4-substitued cholesterol derivatives.
Langmuir 24 (2008) 8807-8812

 
abstract URL

Schön, P., García-Sáez, A. J., Malovrh, P., Bacia, K., Anderluh, G. & Schwille, P.
Equinatoxin II permeabilizing activity depends on the presence of sphingomyelin and lipid phase coexistence.
Biophys J 95 (2008) 691-698

 
abstract URL

Ries, J., Petrov, E. P. & Schwille, P.
Total internal reflection fluorescence correlation spectroscopy: effects of lateral diffusion and surface-generated fluorescence.
Biophys J 95 (2008) 390-399

 
abstract URL

Lingwood, D., Ries, J., Schwille, P. & Simons, K.
Plasma membranes are poised for activation of raft phase coalescence at physiological temperature.
Proc Natl Acad Sci U S A 105 (2008) 10005-10010

 
abstract URL

Felten, M., Staroske, W., Jaeger, M. S., Schwille, P. & Duschl, C.
Accumulation and filtering of nanoparticles in microchannels using electrohydrodynamically induced vortical flows.
Electrophoresis 29 (2008) 2987-2996

 
abstract URL

Ries, J. & Schwille, P.
New concepts for fluorescence correlation spectroscopy on membranes.
Phys Chem Chem Phys 10 (2008) 3487-3497

 
abstract URL

Renner, L., Osaki, T., Chiantia, S., Schwille, P., Pompe, T. & Werner, C.
Supported Lipid Bilayers on Spacious and pH-Responsive Polymer Cushions with Varied Hydrophilicity.
J Phys Chem B 112 (2008) 6373-6378

 
abstract URL

Merkle, D., Zheng, D., Ohrt, T., Crell, K. & Schwille, P.
Cellular dynamics of Ku: characterization and purification of Ku-eGFP.
Chembiochem 9 (2008) 1251-1259

 
abstract URL

Loose, M., Fischer-Friedrich, E., Ries, J., Kruse, K. & Schwille, P.
Spatial regulators for bacterial cell division self-organize into surface waves in vitro.
Science 320 (2008) 789-792

 
abstract URL

Chiantia, S., Ries, J., Chwastek, G., Carrer, D., Li, Z., Bittman, R. & Schwille, P.
Role of ceramide in membrane protein organization investigated by combined AFM and FCS.
Biochim Biophys Acta 1778 (2008) 1356-1364

 
abstract URL

Rajendran, L., Schneider, A., Schlechtingen, G., Weidlich, S., Ries, J., Braxmeier, T., Schwille, P., Schulz, J. B., Schroeder, C., Simons, M., Jennings, G., Knölker, H. & Simons, K.
Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting.
Science 320 (2008) 520-523

 
abstract URL

Petrov, E. P. & Schwille, P.
Translational diffusion in lipid membranes beyond the Saffman-Delbruck approximation.
Biophys J 94 (2008) L41-L43

 
abstract URL

Trajkovic, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B. & Simons, M.
Ceramide triggers budding of exosome vesicles into multivesicular endosomes.
Science 319 (2008) 1244-1247

 
abstract URL

Petrásek, Z. & Schwille, P.
Precise measurement of diffusion coefficients using scanning fluorescence correlation spectroscopy.
Biophys J 94 (2008) 1437-1448

 
abstract URL

Ries, J., Ruckstuhl, T., Verdes, D. & Schwille, P.
Supercritical angle fluorescence correlation spectroscopy.
Biophys J 94 (2008) 221-229

 
abstract URL

Petrásek, Z. & Schwille, P.
Photobleaching in two-photon scanning fluorescence correlation spectroscopy.
Chemphyschem 9 (2008) 147-158

 
abstract URL

Ries, J., Klose, C., Walch-Solimena, C. & Schwille, P.
How to measure slow diffusion in yeast cell membranes.
Proc SPIE 6991 (2008)

 
abstract URL

Petrasek, Z., Hoege, C., Hyman, A.A. & Schwille, P.
Two-photon fluorescence imaging and correlation analysis applied to protein dynamics in C. elegans embryo.
Proc SPIE 6860 (2008)

abstract URL

Petrásek, Z. & Schwille, P.
Scanning fluorescence correlation spectroscopy. In: Single Molecules and Nanotechnology. (Rigler, R. and Vogel, H., eds.)
Springer (2008) 81-106

 
abstract URL

Ohrt, T. & Schwille, P.
siRNA modifications and sub-cellular localization: a question of intracellular transport?
Curr Pharm Des 14 (2008) 3674-3685

 
abstract  

Kahya, N., Merkle, D. & Schwille, P.
Pushing the Complexity of Model Bilayers: Novel Prospects for Membrane Biophysics. In: Fluorescence of Supermolecules, Polymers, and Nanosystems. (M. N. Berberan-Santos, eds.)
Springer (2008) 339-359

 
abstract URL

Haustein, E. & Schwille, P.
Ultrashort Laser Pulses in Single Molecule Spectroscopy. In: Ultrashort Laser Pulses in Biology and Medicine. (M. Braun, P. Gilch and W. Zinth, eds.)
Springer (2008) 279-311

 
abstract URL

Haustein, E. & Schwille, P.
Fluorescence correlation spectrosocpy in vitro and in vivo
Singl-Mol Tech (2008) 259-278

   

Kahya, N. & Schwille, P.
Ceramide-mediated domain organization in giant unilamellar vesicles
Phys Mag 30 (2008) 25-30

   

2007

Mütze, J., Petrásek, Z. & Schwille, P.
Independence of maximum single molecule fluorescence count rate on the temporal and spectral laser pulse width in two-photon FCS.
J Fluoresc 17 (2007) 805-810

 
abstract URL

Kim, S. A., Heinze, K. G. & Schwille, P.
Fluorescence correlation spectroscopy in living cells.
Nat Methods 4 (2007) 963-973

 
abstract URL

García-Sáez, A. J., Chiantia, S. & Schwille, P.
Effect of line tension on the lateral organization of lipid membranes.
J Biol Chem 282 (2007) 33537-33544

 
abstract URL

Baumgärtner, P., Geiger, M., Zieseniss, S., Malleier, J., Huntington, J. A., Hochrainer, K., Bielek, E., Stoeckelhuber, M., Lauber, K., Scherfeld, D., Schwille, P., Wäldele, K., Beyer, K. & Engelmann, B.
Phosphatidylethanolamine critically supports internalization of cell-penetrating protein C inhibitor.
J Cell Biol 179 (2007) 793-804

 
abstract URL

Haustein, E. & Schwille, P.
Trends in fluorescence imaging and related techniques to unravel biological information.
HFSP J 1 (2007) 169-180

 
abstract URL

García-Sáez, A. J. & Schwille, P.
Single molecule techniques for the study of membrane proteins.
Appl Microbiol Biotechnol 76 (2007) 257-266

 
abstract URL

García-Sáez, A. J., Chiantia, S., Salgado, J. & Schwille, P.
Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM.
Biophys J 93 (2007) 103-112

 
abstract URL

Chiantia, S., Kahya, N. & Schwille, P.
Raft Domain Reorganization Driven by Short- and Long-Chain Ceramide: A Combined AFM and FCS Study.
Langmuir 23 (2007) 7659-7665

 
abstract URL

Henkel, A. W., Dittrich, P. S., Groemer, T. W., Lemke, E. A., Klingauf, J., Klafki, H. W., Lewczuk, P., Esselmann, H., Schwille, P., Kornhuber, J. & Wiltfang, J.
Immune complexes of auto-antibodies against Abeta1-42 peptides patrol cerebrospinal fluid of non-Alzheimer's patients.
Mol Psychiatry 12 (2007) 601-610

 
abstract URL

Krishnan, M., Mönch, I. & Schwille, P.
Spontaneous stretching of DNA in a two-dimensional nanoslit.
Nano Lett 7 (2007) 1270-1275

 
abstract URL

Haustein, E. & Schwille, P.
Fluorescence correlation spectroscopy: novel variations of an established technique.
Annu Rev Biophys Biomol Struct 36 (2007) 151-169

 
abstract URL

Petrov, E. & Schwille, P.
State of the art and novel trends in fluorescence correlation spectroscopy. In: Standardization and Quality Assurance in Fluorescence Measurements II. Bioanalytical and Biomedical Applications. (U. Resch-Genger, eds.)
Springer (2008) 145-197

 
abstract URL

Petrásek, Z., Krishnan, M., Mönch, I. & Schwille, P.
Simultaneous two-photon fluorescence correlation spectroscopy and lifetime imaging of dye molecules in submicrometer fluidic structures.
Microsc Res Tech 70 (2007) 459-466

 
abstract URL

Bacia, K. & Schwille, P.
Practical guidelines for dual-color fluorescence cross-correlation spectroscopy.
Nat Protoc 2 (2007) 2842-2856

 
abstract URL

Bacia, K. & Schwille, P.
Fluorescence correlation spectroscopy.
Methods Mol Biol 398 (2007) 73-84

 
abstract  

Schwille, P.
Two-photon cross-correlation spectroscopy: analysing the interactions of single molecules in the live cell.
Wiss Z Tech Unic Dresden 56 (2007) 119-124

   

2006

Petrov, E. P., Ohrt, T., Winkler, R. G. & Schwille, P.
Diffusion and segmental dynamics of double-stranded DNA.
Phys Rev Lett 97APS (2006) 258101

 
abstract URL

Meacci, G., Ries, J., Fischer-Friedrich, E., Kahya, N., Schwille, P. & Kruse, K.
Mobility of Min-proteins in Escherichia coli measured by fluorescence correlation spectroscopy.
Phys Biol 3 (2006) 255-263

 
abstract URL

Chiantia, S., Ries, J., Kahya, N. & Schwille, P.
Combined AFM and two-focus SFCS study of Raft-exhibiting model membranes.
Chemphyschem 7 (2006) 2409-2418

 
abstract URL

Ries, J. & Schwille, P.
Studying slow membrane dynamics with continuous wave scanning fluorescence correlation spectroscopy.
Biophys J 91 (2006) 1915-1924

 
abstract URL

Kahya, N. & Schwille, P.
How phospholipid-cholesterol interactions modulate lipid lateral diffusion, as revealed by fluorescence correlation spectroscopy.
J Fluoresc 16 (2006) 671-678

 
abstract URL

Chiantia, S., Kahya, N., Ries, J. & Schwille, P.
Effects of ceramide on liquid-ordered domains investigated by simultaneous AFM and FCS.
Biophys J 90 (2006) 4500-4508

 
abstract URL

Burkhardt, M. & Schwille, P.
Electron multiplying CCD based detection for spatially resolved fluorescence correlation spectroscopy
Optics Express 14 (2006) 5013-5020

 
abstract URL

Becker, C. F. W., Seidel, R., Jahnz, M., Bacia, K., Niederhausen, T., Alexandrov, K., Schwille, P., Goody, R. S. & Engelhard, M.
C-terminal fluorescence labeling of proteins for interaction studies on the single-molecule level.
Chembiochem 7 (2006) 891-895

 
  URL

Schäfer, S. P., Dittrich, P. S., Petrov, E. P. & Schwille, P.
Single molecule fluorescence imaging of the photoinduced conversion and bleaching behavior of the fluorescent protein Kaede.
Microsc Res Tech 69 (2006) 210-219

 
abstract URL

Ohrt, T., Merkle, D., Birkenfeld, K., Echeverri, C. J. & Schwille, P.
In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5.
Nucleic Acids Res 34 (2006) 1369-1380

 
abstract URL

Becker, W., Bergmann, A., Haustein, E., Petrasek, Z., Schwille, P., Biskup, C., Kelbauskas, L., Benndorf, K., Klöcker, N., Anhut, T., Riemann, I. & König, K.
Fluorescence lifetime images and correlation spectra obtained by multidimensional TCSPC.
Proc SPIE (2006) 144-152

 
abstract  

Becker, W., Bergmann, A., Haustein, E., Petrasek, Z., Schwille, P., Biskup, C., Kelbauskas, L., Benndorf, K., Klöcker, N., Anhut, T., Riemann, I. & König, K.
Fluorescence lifetime images and correlation spectra obtained by multidimensional time-correlated single photon counting.
Microsc Res Tech 69 (2006) 186-195

 
abstract URL

Bacia, K., Kim, S. A. & Schwille, P.
Fluorescence cross-correlation spectroscopy in living cells.
Nat Methods 3 (2006) 83-89

 
abstract URL

Kahya, N. & Schwille, P.
Fluorescence correlation studies of lipid domains in model membranes.
Mol Membr Biol 23 (2006) 29-39

 
abstract URL

Gast, F. U., Dittrich, P. S., Schwille, P., Weigel, M., Mertig, M., Opitz, J., Queitsch, U., Diez, S., Lincoln, B., Wottawah, F., Schinkinger, S., Guck, J., Kas, J., Smolinski, J., Salchert, K., Werner, C., Duschl, C., Jager, M. S., Uhlig, K., Geggier, P. & Howitz, S.
The microscopy cell (MicCell), a versatile modular flowthrough system for cell biology, biomaterial research, and nanotechnology
Microfluidics and Nanofluidics 2 (2006) 21-36

 

2001 - 2005


2005

Kalvodova, L., Kahya, N., Schwille, P., Ehehalt, R., Verkade, P., Drechsel, D. & Simons, K.
Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro.
J Biol Chem 280 (2005) 36815-36823

 
abstract URL

Dittrich, P. S., Schäfer, S. P. & Schwille, P.
Characterization of the photoconversion on reaction of the fluorescent protein Kaede on the single-molecule level.
Biophys J 89 (2005) 3446-3455

 
abstract URL

Kohl, T., Haustein, E. & Schwille, P.
Determining protease activity in vivo by fluorescence cross-correlation analysis.
Biophys J 89 (2005) 2770-2782

 
abstract URL

Burkhardt, M., Heinze, K. G. & Schwille, P.
Four-color fluorescence correlation spectroscopy realized in a grating-based detection platform.
Opt Lett 30 (2005) 2266-2268

 
abstract URL

Chiantia, S., Kahya, N. & Schwille, P.
Dehydration damage of domain-exhibiting supported bilayers: an AFM study on the protective effects of disaccharides and other stabilizing substances.
Langmuir 21 (2005) 6317-6323

 
abstract URL

Kim, S. A., Heinze, K. G., Bacia, K., Waxham, M. N. & Schwille, P.
Two-photon cross-correlation analysis of intracellular reactions with variable stoichiometry.
Biophys J 88 (2005) 4319-4336

 
abstract URL

Kahya, N., Scherfeld, D. & Schwille, P.
Differential lipid packing abilities and dynamics in giant unilamellar vesicles composed of short-chain saturated glycerol-phospholipids, sphingomyelin and cholesterol.
Chem Phys Lipids 135 (2005) 169-180

 
abstract URL

Kahya, N., Brown, D. A. & Schwille, P.
Raft partitioning and dynamic behavior of human placental alkaline phosphatase in giant unilamellar vesicles.
Biochemistry 44 (2005) 7479-7489

 
abstract URL

Jahnz, M., Medina, M. A. & Schwille, P.
A novel homogenous assay for topoisomerase II action and inhibition.
Chembiochem 6 (2005) 920-926

 
abstract URL

Dittrich, P. S., Jahnz, M. & Schwille, P.
A new embedded process for compartmentalized cell-free protein expression and on-line detection in microfluidic devices.
Chembiochem 6 (2005) 811-814

 
  URL

Berezhna, S., Schaefer, S., Heintzmann, R., Jahnz, M., Boese, G., Deniz, A. & Schwille, P.
New effects in polynucleotide release from cationic lipid carriers revealed by confocal imaging, fluorescence cross-correlation spectroscopy and single particle tracking.
Biochim Biophys Acta 1669 (2005) 193-207

 
abstract URL

Bacia, K., Schwille, P. & Kurzchalia, T.
Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes.
Proc Natl Acad Sci U S A 102 (2005) 3272-3277

 
abstract URL

Stagi, M., Dittrich, P. S., Frank, N., Iliev, A. I., Schwille, P. & Neumann, H.
Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide.
J Neurosci 25 (2005) 352-362

 
abstract URL

Gordon, S. P., Berezhna, S., Scherfeld, D., Kahya, N. & Schwille, P.
Characterization of interaction between cationic lipid-oligonucleotide complexes and cellular membrane lipids using confocal imaging and fluorescence correlation spectroscopy.
Biophys J 88 (2005) 305-316

 
abstract URL

Kohl, T. & Schwille, P.
Fluorescence correlation spectroscopy with autofluorescent proteins.
Adv Biochem Eng Biotechnol 95 (2005) 107-142

 
abstract  

Jahnz, M. & Schwille, P.
An ultrasensitive site-specific DNA recombination assay based on dual-color fluorescence cross-correlation spectroscopy.
Nucleic Acids Res 33 (2005) e60

 
abstract URL

Schwille, P.
Fluorescence correlation spectroscopy: Perspectives for in vivo characterization of single-molecule dynamics.
Visions Cell Nucl (2005) 248-267

   

2004

Haustein, E. & Schwille, P.
Single-molecule spectroscopic methods.
Curr Opin Struct Biol 14 (2004) 531-540

 
abstract URL

Böse, G., Schwille, P. & Lamparter, T.
The mobility of phytochrome within protonemal tip cells of the moss Ceratodon purpureus, monitored by fluorescence correlation spectroscopy.
Biophys J 87 (2004) 2013-2021

 
abstract URL

Bacia, K., Schuette, C. G., Kahya, N., Jahn, R. & Schwille, P.
SNAREs prefer liquid-disordered over "raft" (liquid-ordered) domains when reconstituted into giant unilamellar vesicles.
J Biol Chem 279 (2004) 37951-37955

 
abstract URL

Bacia, K., Scherfeld, D., Kahya, N. & Schwille, P.
Fluorescence correlation spectroscopy relates rafts in model and native membranes.
Biophys J 87 (2004) 1034-1043

 
abstract URL

Kahya, N., Scherfeld, D., Bacia, K. & Schwille, P.
Lipid domain formation and dynamics in giant unilamellar vesicles explored by fluorescence correlation spectroscopy.
J Struct Biol 147 (2004) 77-89

 
abstract URL

Jahnz, M. & Schwille, P.
Enzyme assays for confocal single molecule spectroscopy.
Curr Pharm Biotechnol 5 (2004) 221-229

 
abstract URL

Kim, S. A., Heinze, K. G., Waxham, M. N. & Schwille, P.
Intracellular calmodulin availability accessed with two-photon cross-correlation.
Proc Natl Acad Sci U S A 101 (2004) 105-110

 
abstract URL

Heinze, K. G., Jahnz, M. & Schwille, P.
Triple-color coincidence analysis: one step further in following higher order molecular complex formation.
Biophys J 86 (2004) 506-516

 
abstract URL

Dittrich, P. S., Muller, B. & Schwille, P.
Studying reaction kinetics by simultaneous FRET and cross-correlation analysis in a miniaturized continuous flow reactor
PHys Chem Chem Phys 6 (2004) 4416-4420

 
abstract URL

Berezhna, S. & Schwille, P.
Single molecule fluorescence microscopy for studies of non-viral DNA carriers. In: Fluorescence Techniques in Non-Viral Gene Therapy. (N. Adjimatera, A. P. Neal and I. S. Blagbrough, eds.)
Springer (2004) 201-228

 
   

Dittrich, P.S., Jahnz, M. & Schwille, P.
A novel approach for miniaturized in vitro protein expression in microfluidic channels
Spec Publ - R Soc Chem 296 (2004) 52-54

 

   

2003

Scherfeld, D., Kahya, N. & Schwille, P.
Lipid dynamics and domain formation in model membranes composed of ternary mixtures of unsaturated and saturated phosphatidylcholines and cholesterol.
Biophys J 85 (2003) 3758-3768

 
abstract  

Schwille, P.
TIR-FCS: staying on the surface can sometimes be better.
Biophys J 85 (2003) 2783-2784

 
   

Opitz, N., Rothwell, P. J., Oeke, B. & Schwille, P. S.
Single molecule FCS-based oxygen sensor (O-2-FCSensor): a new intrinsically calibrated oxygen sensor utilizing fluorescence correlation spectroscopy (FCS) with single fluorescent molecule detection sensitivity
Sensors and Actuators B-Chemical 96 (2003) 460-467

 
abstract  

Dittrich, P. S. & Schwille, P.
An integrated microfluidic system for reaction, high-sensitivity detection, and sorting of fluorescent cells and particles.
Anal Chem 75 (2003) 5767-5774

 
abstract URL

Pyenta, P. S., Schwille, P., Webb, W. W., Holowka, D. & Baird, B.
Lateral diffusion of membrane lipid-anchored probes before and after aggregation of cell surface IgE-receptors
J Phys Chem A 107 (2003) 8310-8318

 
abstract  

Kim, S. A. & Schwille, P.
Intracellular applications of fluorescence correlation spectroscopy: prospects for neuroscience.
Curr Opin Neurobiol 13 (2003) 583-590

 
abstract  

Kahya, N., Scherfeld, D., Bacia, K., Poolman, B. & Schwille, P.
Probing lipid mobility of raft-exhibiting model membranes by fluorescence correlation spectroscopy.
J Biol Chem 278 (2003) 28109-28115

 
abstract URL

Haustein, E., Jahnz, M. & Schwille, P.
Triple FRET: a tool for studying long-range molecular interactions.
Chemphyschem 4 (2003) 745-748

 
  URL

Haustein, E. & Schwille, P.
Ultrasensitive investigations of biological systems by fluorescence correlation spectroscopy.
Methods 29 (2003) 153-166

 
abstract  

Bacia, K. & Schwille, P.
A dynamic view of cellular processes by in vivo fluorescence auto- and cross-correlation spectroscopy.
Methods 29 (2003) 74-85

 
abstract  

2002

Schwille, P., Koltermann, A. & Kettling, U.
Optical single molecule methods and their application in biophysics and biotechnology.
Naturwiss Rundsch 55 (2002) 237-244

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abstract URL

Kohl, T., Heinze, K. G., Kuhlemann, R., Koltermann, A. & Schwille, P.
A protease assay for two-photon crosscorrelation and FRET analysis based solely on fluorescent proteins.
Proc Natl Acad Sci U S A 99 (2002) 12161-12166

 
abstract URL

Heinze, K. G., Rarbach, M., Jahnz, M. & Schwille, P.
Two-photon fluorescence coincidence analysis: rapid measurements of enzyme kinetics.
Biophys J 83 (2002) 1671-1681

 
abstract  

Dittrich, P. S. & Schwille, P.
Spatial two-photon fluorescence cross-correlation spectroscopy for controlling molecular transport in microfluidic structures.
Anal Chem 74 (2002) 4472-4479

 
abstract  

Medina, M. A. & Schwille, P.
Fluorescence correlation spectroscopy for the detection and study of single molecules in biology.
Bioessays 24 (2002) 758-764

 
abstract URL

Bacia, K., Majoul, I. V. & Schwille, P.
Probing the endocytic pathway in live cells using dual-color fluorescence cross-correlation analysis.
Biophys J 83 (2002) 1184-1193

 
abstract  

Schwille, P. & Haustein, E.
Fluorescence Correlation Spectroscopy: A Tutorial for the Biophysics Textbook Online
BTOL (2002)

 
  URL

Amediek, A., Haustein, E., Scherfeld, D. & Schwille, P.
Scanning dual-color cross-correlation analysis for dynamic co-localization studies of immobile molecules
Single Molecules 3 (2002) 201-210

 
abstract  

2001

Dittrich, P. S. & Schwille, P.
Photobleaching and stabilization of fluorophores used for single-molecule analysis with one- and two-photon excitation
App Phys B 73 (2001) 829-837

 
abstract  

Malvezzi-Campeggi, F., Jahnz, M., Heinze, K. G., Dittrich, P. & Schwille, P.
Light-induced flickering of DsRed provides evidence for distinct and interconvertible fluorescent states.
Biophys J 81 (2001) 1776-1785

 
abstract  

Schwille, P. & Kettling, U.
Analyzing single protein molecules using optical methods.
Curr Opin Biotechnol 12 (2001) 382-386

 
abstract  

Schwille, P.
Fluorescence correlation spectroscopy and its potential for intracellular applications.
Cell Biochem Biophys 34 (2001) 383-408

 
abstract  

Schwille, P. & Heinze, K. G.
Two-photon fluorescence cross-correlation spectroscopy
Chemphyschem 2 (2001) 269-272

 
abstract  

Dittrich, P., Malvezzi-Campeggi, F., Jahnz, M. & Schwille, P.
Accessing molecular dynamics in cells by fluorescence correlation spectroscopy.
Biol Chem 382 (2001) 491-494

 
abstract  

Heinze, G., Koltermann, A. & Schwille, P.
Simultaneous two-photon excitation of distinct labels for dual-color fluorescence crosscorrelation analysis (vol 97, pg 10377, 2000)
Proc Natl Acad Sci U S A 98 (2001) 777-777

 
abstract  

Schwille, P.
Cross-correlation analysis in FCS. In: Fluorescence correlation spectroscopy. Theory and applications. (E.L. Elson and R. Rigler eds.)
Springer (2001) 360-378

 

1996 - 2000


2000

Köhler, R. H., Schwille, P., Webb, W. W. & Hanson, M. R.
Active protein transport through plastid tubules: velocity quantified by fluorescence correlation spectroscopy.
J Cell Sci 113 ( Pt 22) (2000) 3921-3930

 
abstract  

Heinze, K. G., Koltermann, A. & Schwille, P.
Simultaneous two-photon excitation of distinct labels for dual-color fluorescence crosscorrelation analysis.
Proc Natl Acad Sci U S A 97 (2000) 10377-10382

 
abstract URL

Widengren, J. & Schwille, P.
Characterization of photoinduced isomerization and back-isomerization of the cyanine dye Cy5 by fluorescence correlation spectroscopy
J Phys Chem A 104 (2000) 6416-6428

 
abstract  

Schwille, P., Kummer, S., Heikal, A. A., Moerner, W. E. & Webb, W. W.
Fluorescence correlation spectroscopy reveals fast optical excitation-driven intramolecular dynamics of yellow fluorescent proteins.
Proc Natl Acad Sci U S A 97 (2000) 151-156

 
abstract  

1999

Schwille, P., Haupts, U., Maiti, S. & Webb, W. W.
Molecular dynamics in living cells observed by fluorescence correlation spectroscopy with one- and two-photon excitation.
Biophys J 77 (1999) 2251-2265

 
abstract  

Schwille, P., Korlach, J. & Webb, W. W.
Fluorescence correlation spectroscopy with single-molecule sensitivity on cell and model membranes.
Cytometry 36 (1999) 176-182

 
abstract  

Korlach, J., Schwille, P., Webb, W. W. & Feigenson, G. W.
Characterization of lipid bilayer phases by confocal microscopy and fluorescence correlation spectroscopy.
Proc Natl Acad Sci U S A 96 (1999) 8461-8466

 
abstract  

1998

Haupts, U., Maiti, S., Schwille, P. & Webb, W. W.
Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy.
Proc Natl Acad Sci U S A 95 (1998) 13573-13578

 
abstract  

Kettling, U., Koltermann, A., Schwille, P. & Eigen, M.
Real-time enzyme kinetics monitored by dual-color fluorescence cross-correlation spectroscopy.
Proc Natl Acad Sci U S A 95 (1998) 1416-1420

 
abstract  

Bieschke, J. & Schwille, P.
Aggregation of prion protein investigated by dual-color fluorescence cross-correlation spectroscopy
Fluorescent Microscopy and Fluorescent Probes, J.Slavik, ed 2 (1998) 81-86

 
   

1997

Schwille, P., Bieschke, J. & Oehlenschläger, F.
Kinetic investigations by fluorescence correlation spectroscopy: the analytical and diagnostic potential of diffusion studies.
Biophys Chem 66 (1997) 211-228

 
abstract  

Schwille, P., Meyer-Almes, F. J. & Rigler, R.
Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution.
Biophys J 72 (1997) 1878-1886

 
abstract  

Dörre, K., Brakmann, S., Brinkmeier, M., Han, K., Riebeseel, K., Schwille, P., Stephan, J., Wetzel, T., Lapczyna, M., Stuke, M., Bader, R., Hinz, M., Seliger, H., Holm, J., Eigen, M. & Rigler, R.
Techniques for single molecule sequencing.
Bioimaging 5 (1997) 139-152

 
abstract  

1996

Walter, N. G., Schwille, P. & Eigen, M.
Fluorescence correlation analysis of probe diffusion simplifies quantitative pathogen detection by PCR.
Proc Natl Acad Sci U S A 93 (1996) 12805-12810

 
abstract  

Oehlenschläger, F., Schwille, P. & Eigen, M.
Detection of HIV-1 RNA by nucleic acid sequence-based amplification combined with fluorescence correlation spectroscopy.
Proc Natl Acad Sci U S A 93 (1996) 12811-12816

 
abstract  

Schwille, P., Oehlenschläger, F. & Walter, N. G.
Quantitative hybridization kinetics of DNA probes to RNA in solution followed by diffusional fluorescence correlation analysis.
Biochemistry 35 (1996) 10182-10193

 
abstract URL

 

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