Publications of John A. G. Briggs

Tan, A.; Pak, A. J.; Morado, D. R.; Voth, G. A.; Briggs, J. A. G.: Immature HIV-1 assembles from Gag dimers leaving partial hexamers at lattice edges as potential substrates for proteolytic maturation. Proceedings of the National Academy of Sciences of the United States of America 118 (3), e2020054118 (2021)

Tremel, S.; Ohashi, Y.; Morado, D. R.; Bertram, J.; Perisic, O.; Brandt, L. T. L.; von Wrisberg, M. K.; Chen, Z. A.; Maslen, S. L.; Kovtun, O. et al.; Skehel, M.; Rappsilber, J.; Lang, K.; Munro, S.; Briggs, J. A. G.; Williams, R. L.: Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes. Nature Communications 12 (1), 1564 (2021)

Dick, R. A.; Xu, C. Y.; Morado, D. R.; Kravchuk, V.; Ricana, C. L.; Lyddon, T. D.; Broad, A. M.; Feathers, J. R.; Johnson, M. C.; Vogt, V. M. et al.; Perilla, J. R.; Briggs, J. A. G.; Schur, F. K. M.: Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Plos Pathogens 16 (1), e1008277 (2020)

Erlendsson, S.; Morado, D. R.; Cullen, H. B.; Feschotte, C.; Shepherd, J. D.; Briggs, J. A. G.: Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins. Nature Neuroscience 23 (2), pp. 172 - 175 (2020)

Ginger, L.; Malsam, J.; Sonnen, A. F. P.; Morado, D.; Scheutzow, A.; Sollner, T. H.; Briggs, J. A. G.: Arrangements of proteins at reconstituted synaptic vesicle fusion sites depend on membrane separation. Febs Letters 594 (21), pp. 3450 - 3463 (2020)

Ke, Z. L.; Oton, J. Q.; Qu, K.; Cortese, M.; Zila, V.; McKeane, L.; Nakane, T.; Zivanov, J.; Neufeldt, C. J.; Cerikan, B. et al.; Lu, J. M.; Peukes, J.; Xiong, X. L.; Krausslich, H. G.; Scheres, S. H. W.; Bartenschlager, R.; Briggs, J. A. G.: Structures and distributions of SARS-CoV-2 spike proteins on intact virions. Nature 588 (7838), pp. 498 - 502 (2020)

Kovtun, O.; Dickson, V. K.; Kelly, B. T.; Owen, D. J.; Briggs, J. A. G.: Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Science Advances 6 (30), e1008277 (2020)

Malsam, J.; Barfuss, S.; Trimbuch, T.; Zarebidaki, F.; Sonnen, A. F. P.; Wild, K.; Scheutzow, A.; Rohland, L.; Mayer, M. P.; Sinning, I. et al.; Briggs, J. A. G.; Rosenmund, C.; Sollner, T. H.: Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25. Cell Reports 32 (3), 107926 (2020)

Mlcochova, P.; Collier, D.; Ritchie, A.; Assennato, S. M.; Hosmillo, M.; Goel, N.; Meng, B.; Chatterjee, K.; Mendoza, V.; Temperton, N. et al.; Kiss, L.; James, L. C.; Ciazynska, K. A.; Xiong, X. L.; Briggs, J. A. G.; Nathan, J. A.; Mescia, F.; Bergamaschi, L.; Zhang, H. Y.; Barmpounakis, P.; Demeris, N.; Skells, R.; Lyons, P. A.; Bradley, J.; Baker, S.; Allain, J. P.; Smith, K. G. C.; Bousfield, R.; Wilson, M.; Sparkes, D.; Amoroso, G.; Gkrania-Klotsas, E.; Hardwick, S.; Boyle, A.; Goodfellow, I.; Gupta, R. K.; Cambridge Inst Therapeutic, I.: Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant. Cell Reports Medicine 1 (6), 100099 (2020)

Peukes, J.; Xiong, X. L.; Erlendsson, S.; Qu, K.; Wan, W.; Calder, L. J.; Schraidt, O.; Kummer, S.; Freund, S. M. V.; Krausslich, H. G. et al.; Briggs, J. A. G.: The native structure of the assembled matrix protein 1 of influenza A virus. Nature 587 (7834), pp. 495 - 498 (2020)

Wan, W.; Clarke, M.; Norris, M. J.; Kolesnikova, L.; Koehler, A.; Bornholdt, Z. A.; Becker, S.; Saphire, E. O.; Briggs, J. A. G.: Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers. Elife 9, e59225 (2020)

Xiong, X. L.; Qu, K.; Ciazynska, K. A.; Hosmillo, M.; Carter, A. P.; Ebrahimi, S.; Ke, Z. L.; Scheres, S. H. W.; Bergamaschi, L.; Grice, G. L. et al.; Zhang, Y.; Nathan, J. A.; Baker, S.; James, L. C.; Baxendale, H. E.; Goodfellow, I.; Doffinger, R.; Briggs, J. A. G.; Bradley, J.; Lyons, P. A.; Smith, K. G. C.; Toshner, M.; Elmer, A.; Ribeiro, C.; Kourampa, J.; Jose, S.; Kennet, J.; Rowlands, J.; Meadows, A.; O'Brien, C.; Rastall, R.; Crucusio, C.; Hewitt, S.; Price, J.; Calder, J.; Laura, C.; Bucke, A.; Tordesillas, H.; Harris, J.; Ruffolo, V.; Domingo, J.; Graves, B.; Butcher, H.; Caputo, D.; Le Gresley, E.; Dunmore, B. J.; Martin, J.; Legchenko, E.; Treacy, C.; Huang, C.; Wood, J.; Sutcliffe, R.; Hodgson, J.; Shih, J.; Graf, S.; Tong, Z.; Mescia, F.; Tilly, T.; O'Donnell, C.; Hunter, K.; Pointon, L.; Pond, N.; Wylot, M.; Jones, E.; Fawke, S.; Bullman, B.; Bergamaschi, L.; Turner, L.; Jarvis, I.; Omarjee, O.; De Sa, A.; Marsden, J.; Betancourt, A.; Perera, M.; Epping, M.; Richoz, N.; Bower, G.; Sharma, R.; Nice, F.; Huhn, O.; Stark, H.; Walker, N.; Stirrups, K.; Ovington, N.; Dewhust, E.; Li, E.; Papadia, S.; C, C.-N. C.-B.: A thermostable, closed SARS-CoV-2 spike protein trimer. Nature Structural & Molecular Biology 27 (10), pp. 934 - 941 (2020)

Zheng, A.; Sun, W. N.; Xiong, X. L.; Freyn, A. W.; Peukes, J.; Strohmeier, S.; Nachbagauer, R.; Briggs, J. A. G.; Krammer, F.; Palese, P.: Enhancing Neuraminidase Immunogenicity of Influenza A Viruses by Rewiring RNA Packaging Signals. Journal of Virology 94 (16), e00742-20 (2020)

Bykov, Y. S.; Cohen, N.; Gabrielli, N.; Manenschijn, H.; Welsch, S.; Chlanda, P.; Kukulski, W.; Patil, K. R.; Schuldiner, M.; Briggs, J. A. G.: High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding. Journal of Cell Biology 218 (8), pp. 2797 - 2811 (2019)

Dodonova, S. O.; Prinz, S.; Bilanchone, V.; Sandmeyer, S.; Briggs, J. A. G.: Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 116 (20), pp. 10048 - 10057 (2019)

Metskas, L. A.; Briggs, J. A. G.: Fluorescence-Based Detection of Membrane Fusion State on a Cryo-EM Grid using Correlated Cryo-Fluorescence and Cryo-Electron Microscopy. Microscopy and Microanalysis 25 (4), pp. 942 - 949 (2019)

Kovtun, O.; Leneva, N.; Bykov, Y. S.; Ariotti, N.; Teasdale, R. D.; Schaffer, M.; Engel, B. D.; Owen, D. J.; Briggs, J. A. G.; Collins, B. M.: Structure of the membrane-assembled retromer coat determined by cryo-electron tomography. Nature 561 (7724), pp. 561 - 564 (2018)

Mattei, S.; Tana, A.; Glass, B.; Muller, B.; Krausslich, H. G.; Briggs, J. A. G.: High-resolution structures of HIV-1 Gag cleavage mutants determine structural switch for virus maturation. Proceedings of the National Academy of Sciences of the United States of America 115 (40), pp. E9401 - E9410 (2018)

Pastuzyn, E. D.; Day, C. E.; Kearns, R. B.; Kyrke-Smith, M.; Taibi, A. V.; McCormick, J.; Yoder, N.; Belnap, D. M.; Erlendsson, S.; Morado, D. R. et al.; Briggs, J. A. G.; Feschotte, C.; Shepherd, J. D.: The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. Cell 172 (1-2), pp. 275 - 288 (2018)

Pastuzyn, E. D.; Day, C. E.; Kearns, R. B.; Kyrke-Smith, M.; Taibi, A. V.; McCormick, J.; Yoder, N.; Belnap, D. M.; Erlendsson, S.; Morado, D. R. et al.; Briggs, J. A. G.; Feschotte, C.; Shepherd, J. D.: The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer (vol 172, pg 275, 2018). Cell 173 (1), p. 275 - 275 (2018)