Publications of John A. G. Briggs

Journal Article (125)

1.
Journal Article
Banerjee, P.; Qu, K.; Briggs, J. A. G.; Voth, G. A.: Molecular dynamics simulations of HIV-1 matrix-membrane interactions at different stages of viral maturation. Biophysical Journal 123 (3), pp. 389 - 406 (2024)
2.
Journal Article
Highland, C. M.; Tan, A.; Ricana, C. L.; Briggs, J. A. G.; Dick, R. A.: Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18), e2220545120 (2023)
3.
Journal Article
Gaynor, K. U. U.; Vaysburd, M.; Harman, M. A. J.; Albecka, A.; Jeffrey, P.; Beswick, P.; Papa, G.; Chen, L.; Mallery, D.; McGuinness, B. et al.; Van Rietschoten, K.; Stanway, S.; Brear, P.; Lulla, A.; Ciazynska, K.; Chang, V. T. T.; Sharp, J.; Neary, M.; Box, H.; Herriott, J.; Kijak, E.; Tatham, L.; Bentley, E. G. G.; Sharma, P.; Kirby, A.; Han, X.; Stewart, J. P. P.; Owen, A.; Briggs, J. A. G.; Hyvonen, M.; Skynner, M. J. J.; James, L. C. C.: Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2. Nature Communications 14 (1), 3852 (2023)
4.
Journal Article
Stacey, J. C. V.; Tan, A.; Lu, J. M.; James, L. C.; Dick, R. A.; Briggs, J. A. G.: Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding. Proceedings of the National Academy of Sciences of the United States of America 120 (16), e222055712 (2023)
5.
Journal Article
Taylor, R. J.; Tagiltsev, G.; Briggs, J. A. G.: The structure of COPI vesicles and regulation of vesicle turnover. FEBS Letters (2022)
6.
Journal Article
Zivanov, J.; Otón, J.; Ke, Z.; von Kügelgen, A.; Pyle, E.; Qu, K.; Morado, D.; Castaño-Díez, D.; Zanetti, G.; Bharat, T. A. et al.; Briggs, J. A. G.; Scheres, S. H.: A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0. eLife 11, e83724 (2022)
7.
Journal Article
He, P.; Liu, B.; Gao, X.; Yan, Q.; Pei, R.; Sun, J.; Chen, Q.; Hou, R.; Li, Z.; Zhang, Y. et al.; Zhao, J.; Sun, H.; Feng, B.; Wang, Q.; Yi, H.; Hu, P.; Li, P.; Zhang, Y.; Chen, Z.; Niu, X.; Zhong, X.; Jin, L.; Liu, X.; Qu, K.; Ciazynska, K. A.; Carter, A. P.; Briggs, J. A. G.; Chen, J.; Liu, J.; Chen, X.; He, J.; Chen, L.; Xiong, X.: SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nature Microbiology 7, pp. 1635 - 1649 (2022)
8.
Journal Article
Qu, K.; Chen, Q.; Ciazynska, K. A.; Liu, B.; Zhang, X.; Wang, J.; He, Y.; Guan, J.; He, J.; Liu, T. et al.; Zhang, X.; Carter, A. P.; Xiong, X.; Briggs, J. A. G.: Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. PLoS Pathogens 18 (7), e1010583 (2022)
9.
Journal Article
Meng, B.; Abdullahi, A.; Ferreira, I. A. T. M.; Goonawardane, N.; Saito, A.; Kimura, I.; Yamasoba, D.; Gerber, P. P.; Fatihi, S.; Rathore, S. et al.; Zepeda, S. K.; Papa, G.; Kemp, S. A.; Ikeda, T.; Toyoda, M.; Tan, T. S.; Kuramochi, J.; Mitsunaga, S.; Ueno, T.; Shirakawa, K.; Takaori-Kondo, A.; Brevini, T.; Mallery, D. L.; Charles, O. J.; Bowen, J. E.; Joshi, A.; Walls, A. C.; Jackson, L.; Martin, D.; Smith, K. G. C.; Bradley, J.; Briggs, J. A. G.; Choi, J.; Madissoon, E.; Meyer, K. B.; Mlcochova, P.; Ceron-Gutierrez, L.; Doffinger, R.; Teichmann, S. A.; Fisher, A. J.; Pizzuto, M. S.; de Marco, A.; Corti, D.; Hosmillo, M.; Lee, J. H.; James, L. C.; Thukral, L.; Veesler, D.; Sigal, A.; Sampaziotis, F.; Goodfellow, I. G.; Matheson, N. J.; Sato, K.; Gupta, R. K.: Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity. Nature 603, pp. 706 - 714 (2022)
10.
Journal Article
Yu, A.; Lee, E. M. Y.; Briggs, J. A. G.; Ganser-Pornillos, B. K.; Pornillos, O.; Voth, G. A.: Strain and rupture of HIV-1 capsids during uncoating. Proceedings of the National Academy of Sciences of the United States of America 119 (10), e2117781119 (2022)
11.
Journal Article
Pak, A. J.; Yu, A.; Ke, Z.; Briggs, J. A. G.; Voth, G. A.: Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core. Nature Communications 13, 1002 (2022)
12.
Journal Article
Zaccai, N. R.; Kadlecova, Z.; Dickson, V. K.; Korobchevskaya, K.; Kamenicky, J.; Kovtun, O.; Umasankar, P. K.; Wrobel, A. G.; Kaufman, J. G. G.; Gray, S. R. et al.; Qu, K.; Evans, P. R.; Fritzsche, M.; Sroubek, F.; Hoening, S.; Briggs, J. A. G.; Kelly, B. T.; Owen, D. J.; Traub, L. M.: FCHO controls AP2's initiating role in endocytosis through a Ptdlns(4,5)P-2-dependent switch. Science Advances 8 (17), eahn2018 (2022)
13.
Journal Article
Baxendale, H. E.; Wells, D.; Gronlund, J.; Nadesalingham, A.; Paloniemi, M.; Carnell, G.; Tonks, P.; Ceron-Gutierrez, L.; Ebrahimi, S.; Sayer, A. et al.; Briggs, J. A. G.; Ziong, X.; Nathan, J. A.; Grice, G.; James, L. C.; Luptak, J.; Pai, S.; Heeney, J. L.; Lear, S.; Doffinger, R.: Critical Care Workers Have Lower Seroprevalence of SARS-CoV-2 IgG Compared with Non-patient Facing Staff in First Wave of COVID19. Journal of Critical Care Medicine 7 (3), pp. 199 - 210 (2021)
14.
Journal Article
Carnell, G. W.; Ciazynska, K. A.; Wells, D. A.; Xiong, X.; Aguinam, E. T.; McLaughlin, S. H.; Mallery, D.; Ebrahimi, S.; Ceron-Gutierrez, L.; Asbach, B. et al.; Einhauser, S.; Wagner, R.; James, L. C.; Doffinger, R.; Heeney, J. L.; Briggs, J. A. G.; Parrish, C. R.: SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses. Journal of Virology 95 (15), e00203-21 (2021)
15.
Journal Article
Kemp, S. A.; Collier, D. A.; Datir, R. P.; Ferreira, I.; Gayed, S.; Jahun, A.; Hosmillo, M.; Rees-Spear, C.; Mlcochova, P.; Lumb, I. U. et al.; Roberts, D. J.; Chandra, A.; Temperton, N.; Sharrocks, K.; Blane, E.; Modis, Y.; Leigh, K. E.; Briggs, J. A. G.; van Gils, M. J.; Smith, K. G. C.; Bradley, J. R.; Smith, C.; Doffinger, R.; Ceron-Gutierrez, L.; Barcenas-Morales, G.; Pollock, D. D.; Goldstein, R. A.; Smielewska, A.; Skittrall, J. P.; Gouliouris, T.; Goodfellow, I. G.; Gkrania-Klotsas, E.; Illingworth, C. J. R.; McCoy, L. E.; Gupta, R. K.; C, C.-N. B. C.-1.; Consor, C.-G. U. C.-U.: SARS-CoV-2 evolution during treatment of chronic infection. Nature 592 (7853), pp. 277 - 282 (2021)
16.
Journal Article
Leneva, N.; Kovtun, O.; Morado, D. R.; Briggs, J. A. G.; Owen, D. J.: Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly. Science Advances 7 (13), eabf8598 (2021)
17.
Journal Article
Mallery, D. L.; Kleinpeter, A. B.; Renner, N.; Faysal, K. M. R.; Novikova, M.; Kiss, L.; Wilson, M. S. C.; Ahsan, B.; Ke, Z. L.; Briggs, J. A. G. et al.; Saiardi, A.; Bocking, T.; Freed, E. O.; James, L. C.: A stable immature lattice packages IP6 for HIV capsid maturation. Science Advances 7 (11), eabe4716 (2021)
18.
Journal Article
Peukes, J.; Xiong, X.; Briggs, J. A. G.: New structural insights into the multifunctional influenza A matrix protein 1. FEBS Letters 595 (20), pp. 2535 - 2543 (2021)
19.
Journal Article
Qu, K.; Ke, Z. L.; Zila, V.; Anders-Osswein, M.; Glass, B.; Mucksch, F.; Muller, R.; Schultz, C.; Muller, B.; Krausslich, H. G. et al.; Briggs, J. A. G.: Maturation of the matrix and viral membrane of HIV-1. Science 373 (6555), pp. 700 - 704 (2021)
20.
Journal Article
Tan, A.; Pak, A. J.; Morado, D. R.; Voth, G. A.; Briggs, J. A. G.: Immature HIV-1 assembles from Gag dimers leaving partial hexamers at lattice edges as potential substrates for proteolytic maturation. Proceedings of the National Academy of Sciences of the United States of America 118 (3), e2020054118 (2021)
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