Publications of S. Hart

Roidl, A.; Foo, P.; Wong, W.; Mann, C.; Bechtold, S.; Berger, H. J.; Streit, S.; Ruhe, J. E.; Hart, S.; Ullrich, A. et al.; Ho, H. K.: The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cells. Oncogene 29 (10), pp. 1543 - 1552 (2010)

Ho, H. K.; Pok, S.; Streit, S.; Ruhe, J. E.; Hart, S.; Lim, K. S.; Loo, H. L.; Aung, M. O.; Lim, S. G.; Ullrich, A.: Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention. Journal of Hepatology 50 (1), pp. 118 - 127 (2009)

Ruhe, J. E.; Streit, S.; Hart, S.; Wong, C. H.; Specht, K.; Knyazev, P.; Knyazeva, T.; Tay, L. S.; Loo, H. L.; Foo, P. et al.; Wong, W.; Pok, S.; Lim, S. J.; Ong, H.; Luo, M.; Ho, H. V.; Peng, K.; Lee, T. C.; Bezler, M.; Mann, C.; Gaertner, S.; Hoefler, H.; Iacobelli, S.; Peter, S.; Tay, A.; Brenner, S.; Venkatesh, B.; Ullrich, A.: Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines. Cancer Research 67 (23), pp. 11368 - 11376 (2007)

Ruhe, J. E.; Streit, S.; Hart, S.; Ullrich, A.: EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing. Cellular Signalling 18 (9), pp. 1515 - 1527 (2006)

Fischer, O. M.; Hart, S.; Ullrich, A.: Dissecting the epidermal growth factor receptor signal transactivation pathway. Methods in Molecular Biology 327, pp. 85 - 97 (2006)

Hart, S.; Fischer, O. M.; Prenzel, N.; Zwick-Wallasch, E.; Schneider, M.; Hennighausen, L.; Ullrich, A.: GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways. Biological Chemistry 386 (9), pp. 845 - 855 (2005)

Zhao, L.; Hart, S.; Cheng, J. G.; Melenhorst, J. J.; Bierie, B.; Ernst, M.; Stewart, C.; Schaper, F.; Heinrich, P. C.; Ullrich, A. et al.; Robinson, G. W.; Hennighausen, L.: Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK. Journal of Biological Chemistry 279 (42), pp. 44093 - 44100 (2004)

Fischer, O. M.; Hart, S.; Gschwind, A.; Prenzel, N.; Ullrich, A.: Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor. Molecular and Cellular Biology 24 (12), pp. 5172 - 5183 (2004)

Hart, S.; Fischer, O. M.; Ullrich, A.: Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor. Cancer Research 64 (6), pp. 1943 - 1950 (2004)

Fischer, O. M.; Hart, S.; Gschwind, A.; Ullrich, A.: EGFR signal transactivation in cancer cells. Biochemical Society Transactions 31, pp. 1203 - 1208 (2003)

Fischer, O. M.; Streit, S.; Hart, S.; Ullrich, A.: Beyond Herceptin and Gleevec. Current Opinion in Chemical Biology 7 (4), pp. 490 - 495 (2003)

Gschwind, A.; Hart, S.; Fischer, O. M.; Ullrich, A.: TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO Journal 22 (10), pp. 2411 - 2421 (2003)

Hart, S.: Characterisation of the molecular mechanisms of EGFR signal transactivation in human cancer. Dissertation, Julius-Maximilians-Universität, Würzburg (2004)