Publications of Mark S. Hipp

Woerner, A. C.; Frottin, F.; Hornburg, D.; Feng, L. R.; Meissner, F.; Patra, M.; Tatzelt, J.; Mann, M.; Winklhofer, K. F.; Hartl, F. U. et al.; Hipp, M. S.: Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA. Science 351 (6269), pp. 173 - 176 (2016)

Landreh, M.; Sawaya, M. R.; Hipp, M. S.; Eisenberg, D. S.; Wuthrich, K.; Hartl, F. U.: The formation, function and regulation of amyloids: insights from structural biology [Review]. Journal of Internal Medicine 280 (2), pp. 164 - 176 (2016)

Kirstein, J.; Morito, D.; Kakihana, T.; Sugihara, M.; Minnen, A.; Hipp, M. S.; Nussbaum-Krammer, C.; Kasturi, P.; Hartl, F. U.; Nagata, K. et al.; Morimoto, R. I.: Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments. EMBO JOURNAL 34 (18), pp. 2334 - 2349 (2015)

Hipp, M. S.; Park, S.-H.; Hartl, F. U.: Proteostasis impairment in protein-misfolding and -aggregation diseases. Trends in Cell Biology 24 (9), pp. 506 - 514 (2014)

Ripaud, L.; Chumakova, V.; Antonin, M.; Hastie, A. R.; Pinkert, S.; Körner, R.; Ruff, K. M.; Pappu, R. V.; Hornburg, D.; Mann, M. et al.; Hartl, F.-U.; Hipp, M. S.: Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111 (51), pp. 18219 - 18224 (2014)

Park, S.-H.; Kukushkin, Y.; Gupta, R.; Chen, T.; Konagai, A.; Hipp, M. S.; Hayer-Hartl, M.; Hartl, F. U.: PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone. Cell 154 (1), pp. 134 - 145 (2013)

Hipp, M. S.; Bersuker, K.; Kopito, R. R.: Live-cell imaging of ubiquitin-proteasome system function. Methods Mol Biol 832, pp. 463 - 72 (2012)

Hipp, M. S.; Patel, C. N.; Bersuker, K.; Riley, B. E.; Kaiser, S. E.; Shaler, T. A.; Brandeis, M.; Kopito, R. R.: Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease. J Cell Biol 196 (5), pp. 573 - 87 (2012)

Riley, B. E.; Kaiser, S. E.; Shaler, T. A.; Ng, A. C.; Hara, T.; Hipp, M. S.; Lage, K.; Xavier, R. J.; Ryu, K. Y.; Taguchi, K. et al.; Yamamoto, M.; Tanaka, K.; Mizushima, N.; Komatsu, M.; Kopito, R. R.: Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. J Cell Biol 191 (3), pp. 537 - 52 (2010)

Schmidtke, G.; Kalveram, B.; Weber, E.; Bochtler, P.; Lukasiak, S.; Hipp, M. S.; Groettrup, M.: The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10. J Biol Chem 281 (29), pp. 20045 - 54 (2006)

Hipp, M. S.; Kalveram, B.; Raasi, S.; Groettrup, M.; Schmidtke, G.: FAT10, a ubiquitin-independent signal for proteasomal degradation. Mol Cell Biol 25 (9), pp. 3483 - 91 (2005)

Hipp, M. S.; Raasi, S.; Groettrup, M.; Schmidtke, G.: NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation. J Biol Chem 279 (16), pp. 16503 - 10 (2004)

Hipp, M. S.; Urbich, C.; Mayer, P.; Wischhusen, J.; Weller, M.; Kracht, M.; Spyridopoulos, I.: Proteasome inhibition leads to NF-kappaB-independent IL-8 transactivation in human endothelial cells through induction of AP-1. Eur J Immunol 32 (8), pp. 2208 - 17 (2002)

Kim, Y. E.; Hipp, M. S.; Bracher, A.; Hayer-Hartl, M.; Hartl, F. U.: Molecular Chaperone Functions in Protein Folding and Proteostasis. In: ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82, pp. 323 - 355. ANNUAL REVIEWS, 4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0897 USA (2013)

Hipp, M. S.; Bersuker, K.; Kopito, R. R.: Live-Cell Imaging of Ubiquitin–Proteasome System Function. In: Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols, pp. 463 - 472 (Eds. Dohmen, R. J.; Scheffner, M.) (2012)