We are interested in the molecular organization of actin structures in their native environment, and how it enables actin filaments to exert or resist against forces. [more]

Synapses are functional connection points between neurons, transmitting a presynaptic electrical signal (action potential) to the postsynaptic neuron. We use cryo-electron tomography to reveal the architecture of complexes involved in synaptic transmission and to obtain more information about their function. [more]