Publications of F. Ulrich Hartl

Gropp, M. H. M.; Klaips, C. L.; Hartl, F. U.: Formation of toxic oligomers of polyQ-expanded Huntingtin by prion-mediated cross-seeding. Molecular Cell 82 (22), pp. 4290 - 4306 (2022)

Riemenschneider, H.; Guo, Q.; Bader, J.; Frottin, F.; Farny, D.; Kleinberger, G.; Haass, C.; Mann, M.; Hartl, F. U.; Baumeister, W. et al.; Hipp, M. S.; Meissner, F.; Fernandez-Busnadiego, R.; Edbauer, D.: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. EMBO Reports 23, e53890 (2022)

Yuste-Checa, P.; Bracher, A.; Hartl, F. U.: The chaperone Clusterin in neurodegeneration-friend or foe? Bioessays, e2100287 (2022)

Blumenstock, S.; Schulz-Trieglaff, K.; Voelkl, K.; Bolender, A.-L.; Lapios, P.; Lindner, J.; Hipp, M. S.; Hartl, F. U.; Klein, R.; Dudanova, I.: Fluc-EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease. EMBO Journal 40 (19), e107260 (2021)

Frottin, F.; Perez-Berlanga, M.; Hartl, F. U.; Hipp, M. S.: Multiple pathways of toxicity induced by c9orf72 dipeptide repeat aggregates and G(4)C(2) RNA in a cellular model. eLife 10, e62718 (2021)

Schneider, M. M.; Gautam, S.; Herling, T. W.; Andrzejewska, E.; Krainer, G.; Miller, A. M.; Trinkaus, V. A.; Peter, Q. A. E.; Ruggeri, F. S.; Vendruscolo, M. et al.; Bracher, A.; Dobson, C. M.; Hartl, F. U.; Knowles, T. P. J.: The Hsc70 disaggregation machinery removes monomer units directly from alpha-synuclein fibril ends. Nature Communications 12 (1), 5999 (2021)

Sitron, C. S.; Hartl, F. U.: A new way of D/Ealing with protein misfolding. Molecular Cell 81 (20), pp. 4114 - 4115 (2021)

Trinkaus, V. A.; Riera-Tur, I.; Martinez Sanchez, A.; Bäuerlein, F. J. B.; Guo, Q.; Arzberger, T.; Baumeister, W.; Dudanova, I.; Hipp, M. S.; Hartl, F. U. et al.; Fernandez-Busnadiego, R.: In situ architecture of neuronal alpha-Synuclein inclusions. Nature Communications 12 (1), 2110 (2021)

Zang, K.; Wang, H.; Hartl, F. U.; Hayer-Hartl, M.: Scaffolding protein CcmM directs multiprotein phase separation in beta-carboxysome biogenesis. Nature Structural and Molecular Biology 28 (11), pp. 909 - 922 (2021)

Zhao, L.; Castanie-Cornet, M.-P.; Kumar, S.; Genevaux, P.; Hayer-Hartl, M.; Hartl, F. U.: Bacterial RF3 senses chaperone function in co-translational folding. Molecular Cell 81 (14), pp. 2914 - 2928 (2021)

Zinzula, L.; Basquin, J.; Bohn, S.; Beck, F.; Klumpe, S.; Pfeifer, G.; Nagy, I.; Bracher, A.; Hartl, F. U.; Baumeister, W.: High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2 acute respiratory syndrome coronavirus 2. Biochemical and Biophysical Research Communications 538, pp. 54 - 62 (2021)

Flecken, M.; Wang, H.; Popilka, L.; Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes. Cell 183 (2), pp. 457 - 473.e20 (2020)

Balchin, D.; Hayer-Hartl, M.; Hartl, F. U.: Recent advances in understanding catalysis of protein folding by molecular chaperones. FEBS Letters 594, pp. 2770 - 2781 (2020)

Bie, A. S.; Coemert, C.; Körner, R.; Corydon, T. J.; Palmfeldt, J.; Hipp, M. S.; Hartl, F. U.; Bross, P.: An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space. Cell Stress & Chaperones 25, pp. 407 - 416 (2020)

Bracher, A.; Paul, S. S.; Wang, H.; Wischnewski, N.; Hartl, F. U.; Hayer-Hartl, M.: Structure and conformational cycle of a bacteriophage-encoded chaperonin. PLOS ONE 15 (4), e0230090 (2020)

Broch Trentini, D.; Pecoraro, M.; Tiwary, S.; Cox, J.; Mann, M.; Hipp, M. S.; Hartl, F. U.: Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (8), pp. 4099 - 4108 (2020)

Dukovski, D.; Villella, A.; Bastos, C.; King, R.; Finley, D.; Kelly, J. W.; Morimoto, R. I.; Hartl, F. U.; Munoz, B.; Lee, P.-S. et al.; Zecevic, M.; Miller, J. P.: Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA. Journal of cystic fibrosis 19 (5), pp. 733 - 741 (2020)

Hayer-Hartl, M.; Hartl, F. U.: Chaperone Machineries of Rubisco - The Most Abundant Enzyme. Trends in biochemical sciences 45 (9), pp. 748 - 763 (2020)

Herrmann, J. M.; Hartl, F. U.; Pfanner, N.: Mitochondria and friends - a special issue in honor of Walter Neupert (1939-2019). BIOLOGICAL CHEMISTRY 401 (6-7), pp. 643 - 644 (2020)

Imamoglu, R.; Balchin, D.; Hayer-Hartl, M.; Hartl, F. U.: Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein. NATURE COMMUNICATIONS 11 (1), 365 (2020)