Publications of J. Sturzebecher

Journal Article (6)

Journal Article
Zeslawska, E.; Jacob, U.; Sturzebecher, J.; Oleksyn, B. J.: The crystal structures of 3-TAPAP in complexes with the urokinase-type plasminogen activator and picrate. Bioorganic & Medicinal Chemistry Letters 16 (1), pp. 228 - 234 (2006)
Journal Article
Banke, I. J.; Arlt, M. J. E.; Mueller, M. M.; Sperl, S.; Stemberger, A.; Stürzebecher, J.; Amirkhosravi, A.; Moroder, L.; Kruger, A.: Effective inhibition of experimental metastasis and prolongation of survival in mice by a potent factor Xa-specific synthetic serine protease inhibitor with weak anticoagulant activity. Thrombosis and Haemostasis 94 (5), pp. 1084 - 1093 (2005)
Journal Article
Riester, D.; Wirsching, F.; Salinas, G.; Keller, M.; Gebinoga, M.; Kamphausen, S.; Merkwirth, C.; Goetz, R.; Wiesenfeldt, M.; Sturzebecher, J. et al.; Bode, W.; Friedrich, R.; Thurk, M.; Schwienhorst, A.: Thrombin inhibitors identified by computer-assisted multiparameter design. Proceedings of the National Academy of Sciences of the United States of America 102 (24), pp. 8597 - 8602 (2005)
Journal Article
Schweinitz, A.; Steinmetzer, T.; Banke, I. J.; Arlt, M. J. E.; Sturzebecher, A.; Schuster, O.; Geissler, A.; Giersiefen, H.; Zeslawska, E.; Jacob, U. et al.; Kruger, A.; Sturzebecher, J.: Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents. Journal of Biological Chemistry 279 (32), pp. 33613 - 33622 (2004)
Journal Article
Mueller, M. M.; Sperl, S.; Stürzebecher, J.; Bode, W.; Moroder, L.: (R)-3-amidinophenylalanine-derived inhibitors of factor Xa with a novel active-site binding mode. Biological Chemistry 383 (7-8), pp. 1185 - 1191 (2002)
Journal Article
Friedrich, R.; Steinmetzer, T.; Huber, R.; Stürzebecher, J.; Bode, W.: The methyl group of N-alpha(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage. Journal of Molecular Biology 316 (4), pp. 869 - 874 (2002)

Book Chapter (1)

Book Chapter
Bürgle, M.; Sperl, S.; Stürzebecher, J.; Krüger, A.; Schmalix, W.; Kessler, H.; Moroder, L.; Magdolen, V.; Wilhelm, O.G.; Schmitt, M.: The urokinase-type plasminogen activator (uPA) system - A new target for tumor therapy. In: Proteinase and Peptidase Inhibiton: Recent Potential Targets for Drug Development, pp. 231 - 248 (Eds. Smith, H.J.; Simons, C.). Taylor & Francis, London (2002)
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