Publications of Florian Beck

Klumpe, S.; Senti, K. A.; Beck, F.; Sachweh, J.; Hampoelz, B.; Ronchi, P.; Oorschot, V.; Brandstetter, M.; Yeroslaviz, A.; Briggs, J. A. G. et al.; Brennecke, J.; Beck, M.; Plitzko, J. M.: In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography. Cell 188 (8), pp. 2094 - 2110.e18 (2025)

Jerala, R.; Vidmar, S.; Šmidlehner, T.; Aupič, J.; Strmšek, Ž.; Ljubetič, A.; Xiao, F.; Hu, G.; Liu, C.; Beck, F. et al.; Erdmann, P. S.: Beyond Dimerization: Harnessing Tetrameric Coiled‐Coils for Nanostructure Assembly. Angewandte Chemie International Edition 64 (12), e202422075 (2025)

Chakraborty, S.; Martinez Sanchez, A.; Beck, F.; Toro-Nahuelpan, M.; Hwang, I.-Y.; Noh, K.-M.; Baumeister, W.; Mahamid, J.: Cryo-ET suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules. Proceedings of the National Academy of Sciences of the United States of America 122 (5), e2404017121 (2025)

Xu, P.; Schumacher, D.; Liu, C.; Harms, A.; Dickmanns, M.; Beck, F.; Plitzko, J. M.; Baumeister, W.; Søgaard-Andersen, L.: In situ architecture of a nucleoid-associated biomolecular co-condensate that regulates bacterial cell division. Proceedings of the National Academy of Sciences of the United States of America 122 (1), e2419610121 (2025)

Zinzula, L.; Beck, F.; Camasta, M.; Bohn, S.; Liu, C.; Morado, D.; Bracher, A.; Plitzko, J. M.; Baumeister, W.: Cryo-EM structure of single-layered nucleoprotein-RNA complex from Marburg virus. Nature Communications 15 (1), 10307 (2024)

Wagner, J.; Carvajal Alvarez, A. I.; Bracher, A.; Beck, F.; Wan, W.; Bohn, S.; Körner, R.; Baumeister, W.; Fernandez-Busnadiego, R.; Hartl, F. U.: Visualizing chaperonin function in situ by cryo-electron tomography. Nature 633 (8029), pp. 459 - 464 (2024)

Schiotz, O. H.; Kaiser, C. J. O.; Klumpe, S.; Morado, D. R.; Poege, M.; Schneider, J.; Beck, F.; Klebl, D. P.; Thompson, C.; Plitzko, J. M.: Serial Lift-Out: Sampling the molecular anatomy of whole organisms. Nature Methods 21 (9), pp. 1684 - 1692 (2024)

Plitzko, J. M.; Schioetz, O. H.; Kaiser, C. J. O.; Klebl, D. P.; Beck, F.; Brenner, J.; Klumpe, S.: Cryo-FIB Milling for Uni- and Multicellular Samples - the Base for Cryo-Electron Tomography at Molecular Resolution. Microscopy and Microanalysis 30 (Suppl. 1), ozae044969 (2024)

Bieber, A.; Capitanio, C.; Erdmann, P. S.; Fiedler, F.; Beck, F.; Lee, C.-W.; Li, D.; Hummer, G.; Schulman, B. A.; Baumeister, W. et al.; Wilfling, F.: In situ structural analysis reveals membrane shape transitions during autophagosome formation. Proceedings of the National Academy of Sciences of the United States of America 119 (39), e2209823119 (2022)

Jiang, W.; Wagner, J.; Du, W.; Plitzko, J.; Baumeister, W.; Beck, F.; Guo, Q.: A transformation clustering algorithm and its application in polyribosomes structural profiling. Nucleic Acids Research 50 (16), pp. 9001 - 9011 (2022)

Hajarolasvadi, N.; Sunkara, V.; Khavnekar, S.; Beck, F.; Brandt, R.; Baum, D.: Volumetric macromolecule identification in cryo-electron tomograms using capsule networks. BMC Bioinformatics 23 (1), 360 (2022)

Peters, J. J.; Leitz, J.; Guo, Q.; Beck, F.; Baumeister, W.; Brunger, A. T.: A feature-guided, focused 3D signal permutation method for subtomogram averaging. Journal of Structural Biology 214 (2), 107851 (2022)

Khavnekar, S.; Vrbovská, V.; Zaoralová, M.; Kelley, R.; Beck, F.; Klumpe, S.; Kotecha, A.; Plitzko, J.; Erdmann, P. S.: Optimizing Cryo-FIB Lamellas for sub-5Å in situ Structural Biology. bioRxiv: the preprint server for biology (2022)

Erdmann, P. S.; Hou, Z.; Klumpe, S.; Khavnekar, S.; Beck, F.; Wilfling, F.; Plitzko, J. M.; Baumeister, W.: In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Nature Communications 12 (1), 5364 (2021)

Zinzula, L.; Basquin, J.; Bohn, S.; Beck, F.; Klumpe, S.; Pfeifer, G.; Nagy, I.; Bracher, A.; Hartl, F. U.; Baumeister, W.: High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2 acute respiratory syndrome coronavirus 2. Biochemical and Biophysical Research Communications 538, pp. 54 - 62 (2021)

Zinzula, L.; Beck, F.; Klumpe, S.; Bohn, S.; Pfeifer, G.; Bollschweiler, D.; Nagy, I.; Plitzko, J. M.; Baumeister, W.: Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex. Journal of Structural Biology 213 (3), 107750 (2021)

Albert, S.; Wietrzynski, W.; Lee, C.-W.; Schaffer, M.; Beck, F.; Schuller, J. M.; Salome, P. A.; Plitzko, J. M.; Baumeister, W.; Engel, B. D.: Direct visualization of degradation microcompartments at the ER membrane. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (2), pp. 1069 - 1080 (2020)

Jasnin, M.; Beck, F.; Ecke, M.; Fukuda, Y.; Martinez Sanchez, A.; Baumeister, W.; Gerisch, G.: The Architecture of Traveling Actin Waves Revealed by Cryo-Electron Tomography. STRUCTURE 27 (8), pp. 1211 - 1223.e5 (2019)

Majumder, P.; Rudack, T.; Beck, F.; Danev, R.; Pfeifer, G.; Nagy, I.; Baumeister, W.: Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle. Proceedings of the National Academy of Sciences of the United States of America 116 (2), pp. 534 - 539 (2019)

Rast, A.; Schaffer, M.; Albert, S.; Wan, W.; Pfeffer, S.; Beck, F.; Plitzko, J. M.; Nickelsen, J.; Engel, B. D.: Biogenic regions of cyanobacterial thylakoids form contact sites with the plasma membrane. Nature Plants 5 (4), pp. 436 - 446 (2019)