Publications of Brenda A. Schulman

Journal Article (58)

1.
Journal Article
Liwocha, J.; Li, J.; Purser, N.; Rattanasopa, C.; Maiwald, S.; Krist, D. T.; Scott, D. C.; Steigenberger, B.; Prabu, J. R.; Schulman, B. A. et al.; Kleiger, G.: Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature Structural & Molecular Biology 31, pp. 378 - 389 (2024)
2.
Journal Article
Wallace, I.; Baek, K.; Prabu, J. R.; Vollrath, R.; von Gronau, S.; Schulman, B. A.; Swatek, K. N.: Insights into the ISG15 transfer cascade by the UBE1L activating enzyme. Nature Communications 14 (1), 7970 (2023)
3.
Journal Article
Purser, N.; Tripathi-Giesgen, I.; Li, J.; Scott, D. C.; Horn-Ghetko, D.; Baek, K.; Schulman, B. A.; Alpi, A. F.; Kleiger, G.: Catalysis of non-canonical protein ubiquitylation by the ARIH1 ubiquitin ligase. Biochemical Journal 480 (22), pp. 1817 - 1831 (2023)
4.
Journal Article
Henneberg, L. T.; Singh, J.; Duda, D. M.; Baek, K.; Yanishevski, D.; Murray, P. J.; Mann, M.; Sidhu, S. S.; Schulman, B. A.: Activity-based profiling of cullin-RING E3 networks by conformation-specific probes. Nature Chemical Biology (2023)
5.
Journal Article
Hehl, L. A.; Horn-Ghetko, D.; Prabu, J. R.; Vollrath, R.; Tung Vu, D.; Pérez Berrocal, D. A.; Mulder, M. P. C.; van der Heden van Noort, G. J.; Schulman, B. A.: Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5. Nature Chemical Biology (2023)
6.
Journal Article
Hehl, L. A.; Schulman, B. A.: To be (in a transcriptional complex) or not to be (promoting UBR5 ubiquitylation): That is an answer to how degradation controls gene expression. Molecular Cell 83 (15), pp. 2616 - 2618 (2023)
7.
Journal Article
Berrocal, D. A. P. A.; Vishwanatha, T. M.; Horn-Ghetko, D.; Botsch, J. J.; Hehl, L. A.; Kostrhon, S.; Misra, M.; Dikic, I.; Geurink, P. P.; van Dam, H. et al.; Schulman, B. A.; Mulder, M. P. C.: A Pro-Fluorescent Ubiquitin-Based Probe to Monitor Cysteine-Based E3 Ligase Activity. Angewandte Chemie International Edition 62 (32), e202303319 (2023)
8.
Journal Article
Baek, K.; Scott, D. C.; Henneberg, L. T.; King, M. T.; Mann, M.; Schulman, B. A.: Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell 186 (9), pp. 1895 - 1911 (2023)
9.
Journal Article
Scott, D. C.; King, M. T.; Baek, K.; Gee, C. T.; Kalathur, R.; Li, J.; Purser, N.; Nourse, A.; Chai, S. C.; Vaithiyalingam, S. et al.; Chen, T.; Lee, R. E.; Elledge, S. J.; Kleiger, G.; Schulman, B. A.: E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Molecular Cell 83 (5), pp. 770 - 786 (2023)
10.
Journal Article
Li, M.; Tripathi-Giesgen, I.; Schulman, B. A.; Baumeister, W.; Wilfling, F.: In situ snapshots along a mammalian selective autophagy pathway. Proceedings of the National Academy of Sciences of the United States of America 120 (12), e2221712120 (2023)
11.
Journal Article
Nardone, C.; Palanski, B. A.; Scott, D. C.; Timms, R. T.; Barber, K. W.; Gu, X.; Mao, A.; Leng, Y.; Watson, E. V.; Schulman, B. A. et al.; Cole, P. A.; Elledge, S. J.: A central role for regulated protein stability in the control of TFE3 and MITF by nutrients. Molecular Cell 83 (1), pp. 57 - 73 (2023)
12.
Journal Article
Gonzalez, A.; Covarrubias-Pinto, A.; Bhaskara, R. M.; Glogger, M.; Kuncha, S. K.; Xavier, A.; Seemann, E.; Misra, M.; Hoffmann, M. E.; Bräuning, B. et al.; Balakrishnan, A.; Qualmann, B.; Doetsch, V.; Schulman, B. A.; Kessels, M. M.; Huebner, C. A.; Heilemann, M.; Hummer, G.; Dikic, I.: Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum. Nature, pp. 394 - 401 (2023)
13.
Journal Article
Kraus, F.; Goodall, E. A.; Smith, I. R.; Jiang, Y.; Paoli, J. C.; Adolf, F.; Zhang, J.; Paulo, J. A.; Schulman, B. A.; Harper, J. W.: PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems. EMBO Reports, e56399 (2023)
14.
Journal Article
Sherpa, D.; Mueller, J.; Karayel, Ö.; Xu, P.; Yao, Y.; Chrustowicz, J.; Gottemukkala, K. V.; Baumann, C.; Gross, A.; Czarnecki, O. et al.; Zhang, W.; Gu, J.; Nilvebrant, J.; Sidhu, S. S.; Murray, P. J.; Mann, M.; Weiss, M. J.; Schulman, B. A.; Alpi, A. F.: Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation. eLife 11, e77937 (2022)
15.
Journal Article
Dikic, I.; Schulman, B. A.: An expanded lexicon for the ubiquitin code. Nature Reviews Molecular Cell Biology (2022)
16.
Journal Article
Bieber, A.; Capitanio, C.; Erdmann, P. S.; Fiedler, F.; Beck, F.; Lee, C.-W.; Li, D.; Hummer, G.; Schulman, B. A.; Baumeister, W. et al.; Wilfling, F.: In situ structural analysis reveals membrane shape transitions during autophagosome formation. Proceedings of the National Academy of Sciences of the United States of America 119 (39), e2209823119 (2022)
17.
Journal Article
Hopf, L. V.M.; Baek, K.; Klügel, M.; von Gronau, S.; Xiong, Y.; Schulman, B. A.: Structure of CRL7(FBXW)(8) reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation. Nature Structural and Molecular Biology (2022)
18.
Journal Article
Qiao, S.; Lee, C.-W.; Sherpa, D.; Chrustowicz, J.; Cheng, J. D.; Duennebacke, M.; Steigenberger, B.; Karayel, O.; Tung Vu, D.; Gronau, S. v. et al.; Mann, M.; Wilfling, F.; Schulman, B.: Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nature Communications 13 (1), 3041 (2022)
19.
Journal Article
Bludau, I.; Willems, S.; Zeng, W.-F.; Strauss, M. T.; Hansen, F. M.; Tanzer, M. C.; Karayel, O.; Schulman, B. A.; Mann, M.: The structural context of posttranslational modifications at a proteome-wide scale. PLoS Biology 20 (5), e3001636 (2022)
20.
Journal Article
Sherpa, D.; Chrustowicz, J.; Schulman, B.: How the ends signal the end: Regulation by E3 ubiquitin ligases recognizing protein termini. Molecular Cell 82 (8), pp. 1424 - 1438 (2022)
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