Infrastructure

Protein Expression

Kühner shakers for expression in E.coli

Kühner shakers for expression in E.coli

Temperature controlled room for baculovirus-infected insect cell expression

Temperature controlled room for baculovirus-infected insect cell expression

CO2-controlled incubators and shakers for mammalian cell expression

CO2-controlled incubators and shakers for mammalian cell expression


Biochemical and Functional Analyses

Various liquid chromatography systems (Äkta Primes, Purifiers and Avant)

Various liquid chromatography systems (Äkta Primes, Purifiers and Avant)

Isotope lab for 32P-labeled-nucleotide-based activity assays

Isotope lab for 32P-labeled-nucleotide-based activity assays

Dissection microscope and dedicated incubators/shakers for yeast genetics

Dissection microscope and dedicated incubators/shakers for yeast genetics


Crystallisation

Robotics

Robotics

Automatic setup of up to 2400 crystallization conditions with a Phoenix nanodispenser robot from Art Robbins InstrumentsOptimization of crystallization conditions using robotics

Xtal-Focus Imaging Stations

Xtal-Focus Imaging Stations

Xtal-Focus Imaging Stations (Leica/Zeiss microscopes coupled to Thermo Fischer robotic arm and carrousel)Storage of plates in vizualization systems in temperature controlled rooms (4°C, 10°C and 19°C)

In-house X-ray generator D8 Venture (Bruker)

In-house X-ray generator D8 Venture (Bruker)

In-house X-ray generator D8 Venture (Bruker), with the newly developed liquid metal jet X-ray source
D8-Venture


Biophysics

Analytical gel filtration

Analytical gel filtration

Analytical gel filtration on Waters HPLC coupled to Viskotek Static Light Scattering analyzer

Isothermal calorimeter

Isothermal calorimeter

Isothermal calorimeter, fluorescence spectrophotometer for binding affinity estimations

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