Research Interests

Actin-membrane interactions, regulation of focal adhesion proteins

Education & Research Experience

Since 2020 Postdoctoral researcher: MPI of Biochemistry, Petra Schwille Lab
2017-2019 Postdoctoral researcher: MPI of Biochemistry, Naoko Mizuno Lab
2011 - 2016        

PhD in Cell and Molecular Biology, Brandeis University, USA, Avital Rodal Lab

Dissertation: Molecular Mechanisms Regulating Neuronal Membrane Remodeling and Actin Dynamics

2015 Physiology Course, Marine Biology Laboratory, Woods Hole, MA, USA
2011 B.Sc. in Biochemistry, State University of New York at Geneseo

Publications

Litschel TKelley CFHolz DAdeli Koudehi MVogel SKBurbaum LMizuno NVavylonis DSchwille P 
Reconstitution of contractile actomyosin rings in vesicles
bioRxiv (2020) 2020.06.30.180901 [Link]

Kelley CF, Litschel T, Schumacher S, Dedden D, Schwille P, Mizuno N 
Phosphoinositides regulate force-independent interactions between talin, vinculin, and actin
eLife 9 (2020) e56110 [Link]

Dedden D, Schumacher S, Kelley CF, Zacharias M, Biertümpfel C, Fässler R, Mizuno N 
The Architecture of Talin1 Reveals an Autoinhibition Mechanism
Cell 179 (2019) 120-131 [Link]

Stanishneva-Konovalova TB*, Kelley CF*, Eskin TL, Messelaar EM, Wasserman SA, Sokolova OS, Rodal AA
Conformational states underlying autoinhibition of F-BAR domain activity and WASp activation by Nervous Wreck 
PNAS 113 (2016) E5552-61 [Link]
*equal contribution

Kelley CF, Messelaar EM, Eskin T, Wang S ,Song K. , Vishnia K, Becalska AN, Shupliakov O, Hagan MF, Danino D, Sokolova O, Rodal AA 
Membrane charge directs the outcome of F-BAR domain lipid binding and autoregulation 
Cell Reports 13 (2015) 2597-2609 [Link]

Kelley CF, Becalska AN, Berciu C, Nicastro D, Rodal AA 
Assembly of actin filaments and microtubules in Nwk F-BAR-induced membrane deformations 
Communicative and Integrative Biology 8 (2015) e10000703 [Link]

Becalska AN, Kelley CF, Berciu C, Stanishneva-Konovalova TB, Fu X, Wang S, Sokolova OS, Nicastro D, Rodal A.
Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck
Molecular Biology of the Cell 24 (2013) 2406-2418 [Link]

Awards

2019-2021 Marie Curie Individual Fellow
2018-2019 Humboldt Research Fellowship for Post-doctoral Researchers
2017-2018        

EMBO Long-term Fellow

2016 HHMI/Quantitative Biology Interfaces Scholar Award Lecture
2016 MBL Physiology Course Post-Course Research Award
2014 ASCB Compass Outreach Grant
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