Research Group Chromosome Biology
Cell division, Meiosis
Chromosomes are initially linked in pairs, for which a molecular adhesive, cohesin, is required. In the course of meiosis, this adhesive is destroyed again in a precisely coordinated process to ensure the correct separation of the chromosomes during the two meiotic divisions. Wolfgang Zachariae's research group "Chromosome biology" uses unicellular baker's yeast for its investigations. In this simple organism, meiosis occurs in a similar way as in humans and can be investigated using a variety of methods. These include genetics, biochemistry, video microscopy and even computer simulations of biochemical reactions.