Publications of Matthias Mann

Sirinian, C.; Papanastasiou, A. D.; Karayel, O.; Degn, S. E.; Peroukidis, S.; Chaniotis, D.; Nonni, A.; Repanti, M.; Kriegsmann, M.; Makatsoris, T. et al.; Koutras, A.; Mann, M.; Kalofonos, H. P.: Analysis of RANK-c interaction partners identifies TRAF3 as a critical regulator of breast cancer aggressiveness. Neoplasia 33, 100836 (2022)

Mehta, S.; Buyanbat, A.; Kai, Y.; Karayel, O.; Goldman, S. R.; Seruggia, D.; Zhang, K.; Fujiwara, Y.; Donovan, K. A.; Zhu, Q. et al.; Yang, H.; Nabet, B.; Gray, N. S.; Mann, M.; Fischer, E. S.; Adelman, K.; Orkin, S. H.: Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degra-dation of BCL11A protein in erythroid cells. Cell Chemical Biology 29 (8), pp. 1273 - 1287 (2022)

Mund, A.; Coscia, F.; Kriston, A.; Hollandi, R.; Kovacs, F.; Brunner, A. D.; Migh, E.; Schweizer, L.; Santos, A.; Bzorek, M. et al.; Naimy, S.; Rahbek-Gjerdrum, L. M.; Dyring-Andersen, B.; Bulkescher, J.; Lukas, C.; Eckert, M. A.; Lengyel, E.; Gnann, C.; Lundberg, E.; Horvath, P.; Mann, M.: Deep Visual Proteomics defines single-cell identity and heterogeneity. Nature Biotechnology 40, pp. 1231 - 1240 (2022)

Schaller, T.; Maerkl, B.; Claus, R.; Sholl, L.; Hornick, J. L.; Giannetti, M. P.; Schweizer, L.; Mann, M.; Castells, M.: Mast cells in lung damage of COVID-19 autopsies: A descriptive study. Allergy: European Journal of Allergy and Clinical Immunology 77 (7), pp. 2237 - 2239 (2022)

Karayel, O.; Winter, S.; Padmanabhan, S.; Kuras I, Y.; Tung Vu, D.; Tuncali, I.; Merchant, K.; Wills, A.-M.; Scherzer, C. R.; Mann, M.: Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease. Cell Reports Medicine 3 (6), 100661 (2022)

Mund, A.; Brunner, A.-D.; Mann, M.: Unbiased spatial proteomics with single-cell resolution in tissues. Molecular Cell 82 (12), pp. 2335 - 2349 (2022)

Langlois, C. R.; Beier, V.; Karayel, O.; Chrustowicz, J.; Sherpa, D.; Mann, M.; Schulman, B. A.: A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters. EMBO Reports 23 (6), e53835 (2022)

Riemenschneider, H.; Guo, Q.; Bader, J. M.; Frottin, F.; Farny, D.; Kleinberger, G.; Haass, C.; Mann, M.; Hartl, F. U.; Baumeister, W. et al.; Hipp, M. S.; Meissner, F.; Fernandez-Busnadiego, R.; Edbauer, D.: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. EMBO Reports 23 (6), e53890 (2022)

Niu, L.; Thiele, M.; Geyer, P. E.; Rasmussen, D. N.; Webel, H. E.; Santos, A.; Gupta, R.; Meier, F.; Strauss, M. T.; Kjaergaard, M. et al.; Lindvig, K.; Jacobsen, S.; Rasmussen, S.; Hansen, T.; Krag, A.; Mann, M.: Noninvasive proteomic biomarkers for alcohol-related liver disease. Nature Medicine 28 (6), pp. 1277 - 1287 (2022)

Qiao, S.; Lee, C.-W.; Sherpa, D.; Chrustowicz, J.; Cheng, J. D.; Duennebacke, M.; Steigenberger, B.; Karayel, O.; Tung Vu, D.; Gronau, S. v. et al.; Mann, M.; Wilfling, F.; Schulman, B.: Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nature Communications 13 (1), 3041 (2022)

Bludau, I.; Willems, S.; Zeng, W.-F.; Strauss, M. T.; Hansen, F. M.; Tanzer, M. C.; Karayel, O.; Schulman, B. A.; Mann, M.: The structural context of posttranslational modifications at a proteome-wide scale. PLoS Biology 20 (5), e3001636 (2022)

Fan, Y. X.; Murgia, M.; Linder, M. I.; Mizoguchi, Y.; Wang, C.; Lyszkiewicz, M.; Zietara, N.; Liu, Y. S.; Frenz, S.; Sciuccati, G. et al.; Partida-Gaytan, A.; Alizadeh, Z.; Rezaei, N.; Rehling, P.; Dennerlein, S.; Mann, M.; Klein, C.: HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation. The Journal of Clinical Investigation 132 (9), e153153 (2022)

Niu, L.; Geyer, P. E.; Gupta, R.; Santos, A.; Meier, F.; Doll, S.; Albrechtsen, N. J. W.; Klein, S.; Ortiz, C.; Uschner, F. E. et al.; Schierwagen, R.; Trebicka, J.; Mann, M.: Dynamic human liver proteome atlas reveals functional insights into disease pathways. Molecular Systems Biology 18 (5), e10947 (2022)

Kutzner, K.; Woods, S.; Karayel, O.; Gehring, T.; Yin, H.; Flatley, A.; Grass, C.; Wimberger, N.; Tofaute, M. J.; Seeholzer, T. et al.; Feederle, R.; Mann, M.; Krappmann, D.: Phosphorylation of serine-893 in CARD11 suppresses the formation and activity of the CARD11-BCL10-MALT1 complex in T and B cells. Science Signaling 15 (723), eabk3083 (2022)

Riera Tur, I.; Schäfer, T.; Hornburg, D.; Mishra, A.; da Silva Padilha, M.; Fernandez-Mosquera, L.; Feigenbutz, D.; Auer, P.; Mann, M.; Baumeister, W. et al.; Klein, R.; Meissner, F.; Raimundo, N.; Fernandez-Busnadiego, R.; Dudanova, I.: Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity. Life science alliance 5 (3), e202101185 (2022)

Weckbach, L. T.; Schweizer, L.; Kraechan, A.; Bieber, S.; Ishikawa-Ankerhold, H.; Hausleiter, J.; Massberg, S.; Straub, T.; Klingel, K.; Grabmaier, U. et al.; Zwiebel, M.; Mann, M.; Schulz, C.: Association of complement and MAPK activation with SARS-CoV-2-associated myocardial inflammation. JAMA Cardiology 7 (3), pp. 286 - 297 (2022)

Zeller, C.; Richter, D.; Jurinovic, V.; Valtierra-Gutierrez, I. A.; Jayavelu, A. K.; Mann, M.; Bagnoli, J. W.; Hellmann, I.; Herold, T.; Enard, W. et al.; Vick, B.; Jeremias, I.: Adverse stem cell clones within a single patient's tumor predict clinical outcome in AML patients. Journal of Hematology & Oncology 15, 25 (2022)

Brunner, A.-D.; Thielert, M.; Vasilopoulou, C.; Ammar, C.; Coscia, F.; Mund, A.; Hoerning, O. B.; Bache, N.; Apalategui, A.; Lubeck, M. et al.; Richter, S.; Fischer, D. S.; Raether, O.; Park, M. A.; Meier, F.; Theis, F. J.; Mann, M.: Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation. Molecular Systems Biology 18 (3), e10798 (2022)

Schnoeder, T. M.; Schwarzer, A.; Jayavelu, A. K.; Hsu, C. J.; Kirkpatrick, J.; Dohner, K.; Perner, F.; Eifert, T.; Huber, N.; Arreba-Tutusaus, P. et al.; Dolnik, A.; Assi, S. A.; Nafria, M.; Jiang, L.; Dai, Y. T.; Chen, Z.; Chen, S. J.; Kellaway, S. G.; Ptasinska, A.; Ng, E. S.; Stanley, E. G.; Elefanty, A. G.; Buschbeck, M.; Bierhoff, H.; Brodt, S.; Matziolis, G.; Fischer, K. D.; Hochhaus, A.; Chen, C. W.; Heidenreich, O.; Mann, M.; Lane, S. W.; Bullinger, L.; Ori, A.; von Eyss, B.; Bonifer, C.; Heidel, F. H.: PLCG1 is required for AML1-ETO leukemia stem cell self-renewal. Blood 139 (7), pp. 1080 - 1097 (2022)

Perner, F.; Schnoeder, T. M.; Xiong, Y. J.; Jayavelu, A. K.; Mashamba, N.; Santamaria, N. T.; Huber, N.; Todorova, K.; Hatton, C.; Perner, B. et al.; Eifert, T.; Murphy, C.; Hartmann, M.; Hoell, J. I.; Schroder, N.; Brandt, S.; Hochhaus, A.; Mertens, P. R.; Mann, M.; Armstrong, S. A.; Mandinova, A.; Heidel, F. H.: YBX1 mediates translation of oncogenic transcripts to control cell competition in AML. Leukemia 36 (2), pp. 426 - 437 (2022)