Publications of Matthias Mann

Baek, K.; Scott, D. C.; Henneberg, L. T.; King, M. T.; Mann, M.; Schulman, B. A.: Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell 186 (9), pp. 1895 - 1911 (2023)

Ugur, E.; de la Porte, A.; Qin, W.; Bultmann, S.; Ivanova, A.; Drukker, M.; Mann, M.; Wierer, M.; Leonhardt, H.: Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory components. Nucleic Acids Research 51 (6), pp. 2671 - 2690 (2023)

Rosenberger, F. A.; Thielert, M.; Mann, M.: Making single-cell proteomics biologically relevant. Nature Methods 20 (3), pp. 320 - 323 (2023)

Nagao, H.; Cai, W.; Brandao, B. B.; Wewer Albrechtsen, N. J.; Steger, M.; Gattu, A. K.; Pan, H.; Dreyfuss, J. M.; Wunderlich, F. T.; Mann, M. et al.; Kahn, C. R.: Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling. The Journal of Clinical Investigation 133 (4), e161472 (2023)

Bernhardt, A. M.; Tiedt, S.; Teupser, D.; Dichgans, M.; Meyer, B.; Gempt, J.; Kuhn, P.-H.; Simons, M.; Palleis, C.; Weidinger, E. et al.; Nuebling, G.; Holdt, L.; Hoenikl, L.; Gasperi, C.; Giesbertz, P.; Mueller, S. A.; Breimann, S.; Lichtenthaler, S. F.; Kuster, B.; Mann, M.; Imhof, A.; Barth, T.; Hauck, S. M.; Zetterberg, H.; Otto, M.; Weichert, W.; Hemmer, B.; Levin, J.: A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases. EBioMedicine 89, 104456 (2023)

Murgia, M.; Brocca, L.; Monti, E.; Franchi, M. V. V.; Zwiebel, M.; Steigerwald, S.; Giacomello, E.; Sartori, R.; Zampieri, S.; Capovilla, G. et al.; Gasparini, M.; Biolo, G.; Sandri, M.; Mann, M.; Narici, M. V. V.: Plasma proteome profiling of healthy subjects undergoing bed rest reveals unloading-dependent changes linked to muscle atrophy. Journal of Cachexia, Sarcopenia and Muscle 14 (1), pp. 439 - 451 (2023)

Skowronek, P.; Krohs, F.; Lubeck, M.; Wallmann, G.; Itang, E. C. M.; Koval, P.; Wahle, M.; Thielert, M.; Meier, F.; Willems, S. et al.; Raether, O.; Mann, M.: Synchro-PASEF Allows Precursor-Specific Fragment Ion Extraction and Interference Removal in Data-Independent Acquisition. Molecular & Cellular Proteomics 22 (2), 100489 (2023)

Herchenroether, A.; Gossen, S.; Friedrich, T.; Reim, A.; Daus, N.; Diegmueller, F.; Leers, J.; Sani, H. M.; Gerstner, S.; Schwarz, L. et al.; Stellmacher, I.; Szymkowiak, L. V.; Nist, A.; Stiewe, T.; Borggrefe, T.; Mann, M.; Mackay, J. P.; Bartkuhn, M.; Borchers, A.; Lan, J.; Hake, S. B.: The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs. Nature Communications 14 (1), 472 (2023)

Bader, J. M.; Deigendesch, N.; Misch, M.; Mann, M.; Koch, A.; Meissner, F.: Proteomics separates adult-type diffuse high- grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status. Cell Reports Medicine 4 (1), 100877 (2023)

Nagao, H.; Jayavelu, A. K.; Cai, W.; Pan, H.; Dreyfuss, J. M.; Batista, T. M.; Brandão, B. B.; Mann, M.; Kahn, C. R.: Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis. Nature Communications 14, 57 (2023)

Frank, D.; Patnana, P. K.; Vorwerk, J.; Mao, L.; Gopal, L. M.; Jung, N.; Hennig, T.; Ruhnke, L.; Frenz, J. M.; Kuppusamy, M. et al.; Autry, R.; Wei, L.; Sun, K.; Ahmed, H. M. M.; Kuenstner, A.; Busch, H.; Mueller, H.; Hutter, S.; Hoermann, G.; Liu, L.; Xie, X.; Al-Matary, Y.; Nimmagadda, S. C.; Cano, F. C.; Heuser, M.; Thol, F.; Goehring, G.; Steinemann, D.; Thomale, J.; Leitner, T.; Fischer, A.; Rad, R.; Roellig, C.; Altmann, H.; Kunadt, D.; Berdel, W. E.; Hueve, J.; Neumann, F.; Klingauf, J.; Calderon, V.; Opalka, B.; Duehrsen, U.; Rosenbauer, F.; Dugas, M.; Varghese, J.; Reinhardt, H. C.; von Bubnoff, N.; Moroy, T.; Lenz, G.; Batcha, A. M. N.; Giorgi, M.; Selvam, M.; Wang, E.; Mcweeney, S. K.; Tyner, J. W.; Stoelzel, F.; Mann, M.; Jayavelu, A. K.; Khandanpour, C.: Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy. Blood 142 (25), pp. 2175 - 2191 (2023)

Salehi, S.; Zare, A.; Prezza, G.; Bader, J. M.; Schneider, C.; Fischer, U.; Meissner, F.; Mann, M.; Briese, M.; Sendtner, M.: Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr. Nature Communications 14 (1), 4158 (2023)

Bhatia, H. S.; Brunner, A.-D.; Oeztuerk, F.; Kapoor, S.; Rong, Z.; Mai, H.; Thielert, M.; Ali, M.; Al-Maskari, R.; Paetzold, J. C. et al.; Kofler, F.; Todorov, M. I.; Molbay, M.; Kolabas, Z. I.; Negwer, M.; Hoeher, L.; Steinke, H.; Dima, A.; Gupta, B.; Kaltenecker, D.; Caliskan, O. S.; Brandt, D.; Krahmer, N.; Mueller, S.; Lichtenthaler, S. F.; Hellal, F.; Bechmann, I.; Menze, B.; Theis, F.; Mann, M.; Ertuerk, A.: Spatial proteomics in three-dimensional intact specimens. Cell 185 (26), pp. 5040 - 5058 (2022)

Sherpa, D.; Mueller, J.; Karayel, Ö.; Xu, P.; Yao, Y.; Chrustowicz, J.; Gottemukkala, K. V.; Baumann, C. A.; Gross, A.; Czarnecki, O. et al.; Zhang, W.; Gu, J.; Nilvebrant, J.; Sidhu, S. S.; Murray, P. J.; Mann, M.; Weiss, M. J.; Schulman, B. A.; Alpi, A. F.: Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation. eLife 11, e77937 (2022)

Wirth, A.-K.; Wange, L.; Vosberg, S.; Henrich, K.-O.; Rausch, C.; Oezdemir, E.; Zeller, C. M.; Richter, D.; Feuchtinger, T.; Kaller, M. et al.; Hermeking, H.; Greif, P. A.; Senft, D.; Jurinovic, V.; Bahrami, E.; Jayavelu, A. K.; Westermann, F.; Mann, M.; Enard, W.; Herold, T.; Jeremias, I.: In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance. Leukemia 36 (9), pp. 2863 - 2874 (2022)

Reußwig, K.-U.; Bittmann, J.; Peritore, M.; Courtes, M.; Pardo, B.; Wierer, M.; Mann, M.; Pfander, B.: Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions. Nature Communications 13 (1), 7014 (2022)

Yahya, G.; Menges, P.; Amponsah, P. S.; Ngandiri, D. A.; Schulz, D.; Wallek, A. U.; Kulak, N. A.; Mann, M.; Cramer, P.; Savage, V. et al.; Raeschle, M.; Storchova, Z.: Sublinear scaling of the cellular proteome with ploidy. Nature Communications 13 (1), 6182 (2022)

Diamanti, K.; Cavalli, M.; Pereira, M. J.; Pan, G.; Castillejo-Lopez, C.; Kumar, C.; Mundt, F.; Komorowski, J.; Deshmukh, A. S.; Mann, M. et al.; Korsgren, O.; Eriksson, J. W.; Wadelius, C.: Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues. Cell Reports Medicine 3 (10), 100763 (2022)

Skowronek, P.; Thielert, M.; Voytik, E.; Tanzer, M. C.; Hansen, F. M.; Willems, S.; Karayel, O.; Brunner, A.-D.; Meier, F.; Mann, M.: Rapid and in-depth coverage of the (phospho-) proteome with deep libraries and optimal window design for dia-PASEF. Molecular & Cellular Proteomics 21 (9), 100279 (2022)

Meissner, F.; Geddes-McAlister, J.; Mann, M.; Bantscheff, M.: The emerging role of mass spectrometry-based proteomics in drug discovery. Nature Reviews Drug Discovery 21 (9), pp. 637 - 654 (2022)