Publications of Florian Beck

Eisele, M. R.; Reed, R. G.; Rudack, T.; Schweitzer, A.; Beck, F.; Nagy, I.; Pfeifer, G.; Plitzko, J. M.; Baumeister, W.; Tomko Jr., R. J. et al.; Sakata, E.: Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating. Cell Reports 24 (5), pp. 1301 - 1315.e5 (2018)

Guo, Q.; Lehmer, C.; Martinez Sanchez, A.; Rudack, T.; Beck, F.; Hartmann, H.; Perez-Berlanga, M.; Frottin, F.; Hipp, M. S.; Hartl, F. U. et al.; Edbauer, D.; Baumeister, W.; Fernandez-Busnadiego, R.: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell 172 (4), pp. 696 - 705.e12 (2018)

Wehmer, M.; Rudack, T.; Beck, F.; Aufderheide, A.; Pfeifer, G.; Plitzko, J. M.; Förster, F.; Schulten, K.; Baumeister, W.; Sakata, E.: Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proceedings of the National Academy of Sciences of the United States of America 114 (6), pp. 1305 - 1310 (2017)

Albert, S.; Schaffer, M.; Beck, F.; Mosalaganti, S.; Asano, S.; Thomas, H. F.; Plitzko, J. M.; Beck, M.; Baumeister, W.; Engel, B. D.: Proteasomes tether to two distinct sites at the nuclear pore complex. Proceedings of the National Academy of Sciences of the United States of America 114 (52), pp. 13726 - 13731 (2017)

Fukuda, Y.; Beck, F.; Plitzko, J. M.; Baumeister, W.: In situ structural studies of tripeptidyl peptidase II (TPPII) reveal spatial association with proteasomes. Proceedings of the National Academy of Sciences of the United States of America 114 (17), pp. 4412 - 4417 (2017)

Wang, X.; Cimermancic, P.; Yu, C.; Schweitzer, A.; Chopra, N.; Engel, J. L.; Greenberg, C.; Huszagh, A. S.; Beck, F.; Sakata, E. et al.; Yang, Y.; Novitsky, E. J.; Leitner, A.; Nanni, P.; Kahraman, A.; Guo, X.; Dixon, J. E.; Rychnovsky, S. D.; Aebersold, R.; Baumeister, W.; Sali, A.; Huang, L.: Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Molecular and Cellular Proteomics 16 (5), pp. 840 - 854 (2017)

Schuller, J. M.; Beck, F.; Lossl, P.; Heck, A. J. R.; Förster, F.: Nucleotide-dependent conformational changes of the AAA+ ATPase p97 revisited. FEBS LETTERS 590 (5), pp. 595 - 604 (2016)

Schweitzer, A.; Aufderheide, A.; Rudack, T.; Beck, F.; Pfeifer, G.; Plitzko, J. M.; Sakata, E.; Schulten, K.; Förster, F.; Baumeister, W.: Structure of the human 26S proteasome at a resolution of 3.9 angstrom. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113 (28), pp. 7816 - 7821 (2016)

Asano, S.; Fukuda, Y.; Beck, F.; Aufderheide, A.; Förster, F.; Danev, R.; Baumeister, W.: A molecular census of 26S proteasomes in intact neurons. SCIENCE 347 (6220), pp. 439 - 442 (2015)

Aufderheide, A.; Beck, F.; Stengel, F.; Hartwig, M.; Schweitzer, A.; Pfeifer, G.; Goldberg, A. L.; Sakata, E.; Baumeister, W.; Förster, F.: Structural characterization of the interaction of Ubp6 with the 26S proteasome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112 (28), pp. 8626 - 8631 (2015)

Unverdorben, P.; Beck, F.; Sledz, P.; Schweitzer, A.; Pfeifer, G.; Plitzko, J. M.; Baumeister, W.; Förster, F.: Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111 (15), pp. 5544 - 5549 (2014)

Sledz, P.; Unverdorben, P.; Beck, F.; Pfeifer, G.; Schweitzer, A.; Förster, F.; Baumeister, W.: Structure of the 26S proteasome with ATP-gamma S bound provides insights into the mechanism of nucleotide-dependent substrate translocation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110 (18), pp. 7264 - 7269 (2013)

Bohn, S.; Sakata, E.; Beck, F.; Pathare, G. R.; Schnitger, J.; Nagy, I.; Baumeister, W.; Förster, F.: Localization of the regulatory particle subunit Semi in the 26S proteasome. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 435 (2), pp. 250 - 254 (2013)

Beck, F.; Unverdorben, P.; Bohn, S.; Schweitzer, A.; Pfeifer, G.; Sakata, E.; Nickell, S.; Plitzko, J. M.; Villa, E.; Baumeister, W. et al.; Förster, F.: Near-atomic resolution structural model of the yeast 26S proteasome. Proceedings of the National Academy of Sciences of the United States of America 109 (37), pp. 14870 - 14875 (2012)

Lasker, K.; Förster, F.; Bohn, S.; Walzthoeni, T.; Villa, E.; Unverdorben, P.; Beck, F.; Aebersold, R.; Sali, A.; Baumeister, W.: Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proceedings of the National Academy of Sciences of the United States of America 109 (5), pp. 1380 - 1387 (2012)

Sakata, E.; Bohn, S.; Mihalache, O.; Kiss, P.; Beck, F.; Nagy, I.; Nickell, S.; Tanaka, K.; Saeki, Y.; Förster, F. et al.; Baumeister, W.: Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America 109 (5), pp. 1479 - 1484 (2012)

Korinek, A.; Beck, F.; Baumeister, W.; Nickell, S.; Plitzko, J. M.: Computer controlled cryo-electron microscopy - TOM2 a software package for high-throughput applications. Journal of Structural Biology 175 (3), pp. 394 - 405 (2011)

Bohn, S.; Beck, F.; Sakata, E.; Walzthoeni, T.; Beck, M.; Aebersold, R.; Förster, F.; Baumeister, W.; Nickell, S.: Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Proceedings of the National Academy of Sciences of the United States of America 107 (49), pp. 20992 - 20997 (2010)

Stölken, M.; Beck, F.; Haller, T.; Hegerl, R.; Gutsche, I.; Carazo, J. M.; Baumeister, W.; Scheres, S. H. W.; Nickell, S.: Maximum likelihood based classification of electron tomographic data. Journal of Structural Biology 173 [2011] (1), pp. 77 - 85 (2010)

Förster, F.; Lasker, K.; Beck, F.; Nickell, S.; Sali, A.; Baumeister, W.: An atomic model AAA-ATPase/20S core particle sub-complex ofthe 26S proteasome. Biochemical and Biophysical Research Communications 388 (2), pp. 228 - 233 (2009)