Publications of Reinhard Fässler

Thievessen, I.; Suhr, F.; Vergarajauregui, S.; Böttcher, R. T.; Brixius, K.; Rosenberger, G.; Dewald, O.; Fleischmann, B. K.; Ghanem, A.; Kruger, M. et al.; Engel, F. B.; Fabry, B.; Bloch, W.; Fässler, R.: The focal adhesion protein beta-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load. Current Biology 32 (14), pp. 3033 - 3047 (2022)

de Faria, J. P.; Vale-Silva, R. S.; Fässler, R.; Werner, H. B.; Relvas, J. B.: Pinch2 regulates myelination in the mouse central nervous system. Development 149 (13), dev200597 (2022)

Zuidema, A.; Atherton, P.; Kreft, M.; Hoekman, L.; Bleijerveld, O. B.; Nagaraj, N.; Chen, N.; Fässler, R.; Sonnenberg, A.: PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins. Journal of Cell Biology 221 (8), e202108027 (2022)

Zuidema, A.; Wang, W.; Kreft, M.; Bleijerveld, O. B.; Hoekman, L.; Aretz, J.; Böttcher, R. T.; Fässler, R.; Sonnenberg, A.: Molecular determinants of alpha V beta 5 localization in flat clathrin lattices - role of alpha V beta 5 in cell adhesion and proliferation. Journal of Cell Science 135 (11), jcs259465 (2022)

Böttcher, R. T.; Strohmeyer, N.; Aretz, J.; Fässler, R.: New insights into the phosphorylation of the threonine motif of the β1 integrin cytoplasmic domain. Life science alliance 5 (4), e202101301 (2022)

Fischer, A.; Wannemacher, J.; Christ, S.; Koopmans, T.; Kadri, S.; Zhao, J. K.; Gouda, M.; Ye, H. F.; Muck-Hausl, M.; Krenn, P. W. et al.; Machens, H. G.; Fässler, R.; Neumann, P. A.; Hauck, S. M.; Rinkevich, Y.: Neutrophils direct preexisting matrix to initiate repair in damaged tissues. Nature Immunology 23 (4), pp. 518 - 531 (2022)

Chen, N.-P.; Aretz, J.; Fässler, R.: CDK1-cyclin-B1-induced kindlin degradation drives focal adhesion disassembly at mitotic entry. Nature Cell Biology (2022)

Sevilla-Movilla, S.; Fuentes, P.; Rodriguez-Garcia, Y.; Arellano-Sanchez, N.; Krenn, P. W.; Isern de Val, S.; Montero-Herradon, S.; Garcia-Ceca, J.; Burdiel-Herencia, V.; Gardeta, S. R. et al.; Aguilera-Montilla, N.; Barrio-Alonso, C.; Crainiciuc, G.; Bouvard, D.; Garcia-Pardo, A.; Zapata, A. G.; Hidalgo, A.; Fässler, R.; Carrasco, Y. R.; Toribio, M. L.; Teixido, J.: ICAP-1 loss impairs CD8(+) thymocyte development and leads to reduced marginal zone B cells in mice. European Journal of Immunology (2022)

Shi, Y.; Berking, A.; Baade, T.; Legate, K. R.; Fässler, R.; Hauck, C. R.: PIP5KI gamma 90-generated phosphatidylinositol-4,5-bisphosphate promotes the uptake of Staphylococcus aureus by host cells. Molecular Microbiology 116, pp. 1249 - 1267 (2021)

Bulus, N.; Brown, K. L.; Mernaugh, G.; Böttcher, A.; Dong, X.; Sanders, C. R.; Pozzi, A.; Fässler, R.; Zent, R.: Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice. The Journal of Biological Chemistry 296, 100361 (2021)

Fischer, L.; Klingner, C.; Schlichthärle, T.; Strauss, M. T.; Böttcher, R. T.; Fässler, R.; Jungmann, R.; Grashoff, C.: Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion. Nature Communications 12 (1), 919 (2021)

Guo, S. S.; Seiwert, A.; Szeto, I. Y.Y.; Fässler, R.: Tissue distribution and subcellular localization of the family of Kidney Ankyrin Repeat Domain (KANK) proteins. Experimental Cell Research 398 (1), 112391 (2021)

Mole, M. A.; Weberling, A.; Fässler, R.; Campbell, A.; Fishel, S.; Zernicka-Goetz, M.: Integrin beta 1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition. Cell Reports 34 (10), 108834 (2021)

Orre, T.; Joly, A.; Karatas, Z.; Kastberger, B.; Cabriel, C.; Böttcher, R. T.; Leveque-Fort, S.; Sibarita, J.-B.; Fässler, R.; Wehrle-Haller, B. et al.; Rossier, O.; Giannone, G.: Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions. Nature Communications 12 (1), 3104 (2021)

Rabanal-Ruiz, Y.; Byron, A.; Wirth, A.; Madsen, R.; Sedlackova, L.; Hewitt, G.; Nelson, G.; Stingele, J.; Wills, J. C.; Zhang, T. et al.; Zeug, A.; Faessler, R.; Vanhaesebroeck, B.; Maddocks, O. D. K.; Ponimaskin, E.; Carroll, B.; Korolchuk I, V.: mTORC1 activity is supported by spatial association with focal adhesions. The Journal of Cell Biology 220 (5), e202004010 (2021)

Ruiz-Ojeda, F. J.; Wang, J.; Baecker, T.; Krueger, M.; Zamani, S.; Rosowski, S.; Gruber, T.; Onogi, Y.; Feuchtinger, A.; Schulz, T. J. et al.; Faessler, R.; Mueller, T. D.; Garcia-Caceres, C.; Meier, M.; Blueher, M.; Ussar, S.: Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis. Molecular Metabolism 45, 101147 (2021)

Brod, F.; Fässler, R.: A FAK conundrum is solved: activation and organization of focal adhesion kinase at the plasma membrane. EMBO Journal 39, e106234 (2020)

Benito-Jardon, M.; Strohmeyer, N.; Ortega-Sanchis, S.; Bharadwaj, M.; Moser, M.; Mueller, D. J.; Fässler, R.; Costell, M.: alpha v-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation. The Journal of Cell Biology 219 (12), e202004198 (2020)

Guo, S. S.; Au, T. Y. K.; Wynn, S.; Aszodi, A.; Chan, D.; Fässler, R.; Cheah, K. S. E.: beta 1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs. Development 147 (22), dev192724 (2020)

Krenn, P. W.; Koschmieder, S.; Fässler, R.: Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches. Proceedings of the National Academy of Sciences of the United States of America 117 (39), pp. 24326 - 24335 (2020)