Publications of R. Huber

Krapp, S.; Munster-Kuhnel, A. K.; Kaiser, J. T.; Huber, R.; Tiralongo, J.; Gerardy-Schahn, R.; Jacob, U.: The crystal structure of murine CMP-5-N-acetylneuraminic acid synthetase. Journal of Molecular Biology 334 (4), pp. 625 - 637 (2003)

Breitenlechner, C.; Gassel, M.; Hidaka, H.; Kinzel, V.; Huber, R.; Engh, R. A.; Bossemeyer, D.: Protein kinase a in complex with rho-kinase inhibitors Y-27632, fasudil, and H-1152P: Structural basis of selectivity. Structure 11 (12), pp. 1595 - 1607 (2003)

Steinbacher, S.; Schiffmann, S.; Richter, G.; Huber, R.; Bacher, A.; Fischer, M.: Structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with divalent metal ions and the substrate ribulose 5-phosphate - Implications for the catalytic mechanism. Journal of Biological Chemistry 278 (43), pp. 42256 - 42265 (2003)

Friedrich, R.; Panizzi, P.; Fuentes-Prior, P.; Richter, K.; Verhamme, I.; Anderson, P. J.; Kawabata, S. I.; Huber, R.; Bode, W.; Bock, P. E.: Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation. Nature 425 (6957), pp. 535 - 539 (2003)

Almeida, M. G.; Macieira, S.; Goncalves, L. L.; Huber, R.; Cunha, C. A.; Romao, M. J.; Costa, C.; Lampreia, J.; Moura, J. J. G.; Moura, I.: The isolation and characterization of cytochrome c nitrite reductase subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774 - Re-evaluation of the spectroscopic data and redox properties. European Journal of Biochemistry 270 (19), pp. 3904 - 3915 (2003)

Macieira, S.; Martins, B. M.; Huber, R.: Oxygen-dependent coproporphyrinogen-III oxidase from Escherichia coli: one-step purification and biochemical characterisation. FEMS Microbiology Letters 226 (1), pp. 31 - 37 (2003)

Jozic, D.; Kaiser, J. T.; Huber, R.; Bode, W.; Maskos, K.: X-ray structure of isoaspartyl dipeptidase from E-coli: A dinuclear zinc peptidase evolved from amidohydrolases. Journal of Molecular Biology 332 (1), pp. 243 - 256 (2003)

Breithaupt, C.; Schubart, A.; Zander, H.; Skerra, A.; Huber, R.; Linington, C.; Jacob, U.: Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein. Proceedings of the National Academy of Sciences of the United States of America 100 (16), pp. 9446 - 9451 (2003)

Blaesse, M.; Kupke, T.; Huber, R.; Steinbacher, S.: Structure of MrsD, an FAD-binding protein of the HFCD family. Acta Crystallographica Section D-Biological Crystallography 59, pp. 1414 - 1421 (2003)

Gerhardt, S.; Echt, S.; Busch, M.; Freigang, J.; Auerbach, G.; Bader, G.; Martin, W. F.; Bacher, A.; Huber, R.; Fischer, M.: Structure and properties of an engineered transketolase from maize. Plant Physiology 132 (4), pp. 1941 - 1949 (2003)

Wendt, K. S.; Schall, I.; Huber, R.; Buckel, W.; Jacob, U.: Crystal structure of the carboxyltransferase subunit of the bacterial sodium ion pump glutaconyl-coenzyme A decarboxylase. EMBO Journal 22 (14), pp. 3493 - 3502 (2003)

Henrich, S.; Cameron, A.; Bourenkov, G. P.; Kiefersauer, R.; Huber, R.; Lindberg, I.; Bode, W.; Than, M. E.: The crystal structure of the proprotein processing proteinase furin explains its stringent specificity. Nature Structural Biology 10 (7), pp. 520 - 526 (2003)

Gassel, M.; Breitenlechner, C. B.; Ruger, P.; Jucknischke, U.; Schneider, T.; Huber, R.; Bossemeyer, D.; Engh, R. A.: Mutants of protein kinase a that mimic the ATP-binding site of protein kinase B (AKT). Journal of Molecular Biology 329 (5), pp. 1021 - 1034 (2003)

Steinbacher, S.; Kaiser, J.; Gerhardt, S.; Eisenreich, W.; Huber, R.; Bacher, A.; Rohdich, F.: Crystal structure of the type II isopentenyl diphosphate: Dimethylallyl diphosphate isomerase from Bacillus subtilis. Journal of Molecular Biology 329 (5), pp. 973 - 982 (2003)

Augustin, M. A.; Reichert, A. S.; Betat, H.; Huber, R.; Morl, M.; Steegborn, C.: Crystal structure of the human CCA-adding enzyme: Insights into template-independent polymerization. Journal of Molecular Biology 328 (5), pp. 985 - 994 (2003)

Bae, J. H.; Rubini, M.; Jung, G.; Wiegand, G.; Seifert, M. H. J.; Azim, M. K.; Kim, J. S.; Zumbusch, A.; Holak, T. A.; Moroder, L. et al.; Huber, R.; Budisa, N.: Expansion of the genetic code enables design of a novel "gold'' class of green fluorescent proteins. Journal of Molecular Biology 328 (5), pp. 1071 - 1081 (2003)

Steinbacher, S.; Kaiser, J.; Eisenreich, W.; Huber, R.; Bacher, A.; Rohdich, F.: Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC) - Implications for the catalytic mechanism and anti-malaria drug development. Journal of Biological Chemistry 278 (20), pp. 18401 - 18407 (2003)

Cunha, C. A.; Macieira, S.; Dias, J. M.; Almeida, G.; Goncalves, L. L.; Costa, C.; Lampreia, J.; Huber, R.; Moura, J. J. G.; Moura, I. et al.; Romao, M. J.: Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774 - The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA). Journal of Biological Chemistry 278 (19), pp. 17455 - 17465 (2003)

Groll, M.; Huber, R.: Substrate access and processing by the 20S proteasome core particle. International Journal of Biochemistry & Cell Biology 35 (5), pp. 606 - 616 (2003)

Engel, M.; Hoffmann, T.; Wagner, L.; Wermann, M.; Heiser, U.; Kiefersauer, R.; Huber, R.; Bode, W.; Demuth, H. U.; Brandstetter, H.: The crystal structure of dipeptidyl peptidase IV(CD26) reveals its functional regulation and enzymatic mechanism. Proceedings of the National Academy of Sciences of the United States of America 100 (9), pp. 5063 - 5068 (2003)