Publications of Robert Huber
All genres
Journal Article (208)
1.
Journal Article
Facile Multicomponent Synthesis of Oxazolidinones from Primary Amines and Cesium (Hydrogen)Carbonate. European Journal of Organic Chemistry, e202300135 (2023)
2.
Journal Article
Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angewandte Chemie International Edition, e202210498 (2022)
3.
Journal Article
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair. EMBO Reports, e54136 (2022)
4.
Journal Article
7 (2), eabd4413 (2021)
Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Science Advances 5.
Journal Article
117 (6), pp. 2894 - 2905 (2020)
A precisely positioned MED12 activation helix stimulates CDK8 kinase activity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 6.
Journal Article
117 (3), pp. 1414 - 1418 (2020)
Activation by substoichiometric inhibition. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 7.
Journal Article
115 (17), pp. E3932 - E3939 (2018)
Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues. Proceedings of the National Academy of Sciences of the United States of America 8.
Journal Article
115 (7), pp. E1437 - E1445 (2018)
Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer. Proceedings of the National Academy of Sciences of the United States of America 9.
Journal Article
113 (40), pp. 11196 - 11201 (2016)
Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proceedings of the National Academy of Sciences of the United States of America 10.
Journal Article
21 (47), pp. 16887 - 16894 (2015)
Design, Synthesis, and Biological Evaluation of Quercetagetin Analogues as JNK1 Inhibitors. CHEMISTRY-A EUROPEAN JOURNAL 11.
Journal Article
98 (3), pp. 473 - 483 (2015)
Flt3 is a target of coumestrol in protecting against UVB-induced skin photoaging. BIOCHEMICAL PHARMACOLOGY 12.
Journal Article
111 (46), pp. 16496 - 16501 (2014)
Cerebral small vessel disease-related protease HtrA1 processes latent TGF-beta binding protein 1 and facilitates TGF-beta signaling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 13.
Journal Article
70, pp. 1224 - 1232 (2014)
IR laser-induced protein crystal transformation. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 14.
Journal Article
426 (22), pp. 3744 - 3756 (2014)
Structural Analysis of the Human Fibroblast Growth Factor Receptor 4 Kinase. JOURNAL OF MOLECULAR BIOLOGY 15.
Journal Article
425 (2), pp. 411 - 423 (2013)
Structural and Functional Analysis of the Natural JNK1 Inhibitor Quercetagetin. JOURNAL OF MOLECULAR BIOLOGY 16.
Journal Article
52 (1), pp. 68 - 73 (2013)
"How I Chose Research on Proteases or, More Correctly, How it Chose Me". ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 17.
Journal Article
110 (20), pp. 8081 - 8086 (2013)
Structure-kinetic relationship study of CDK8/CycC specific compounds. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 18.
Journal Article
287 (25), pp. 20931 - 20941 (2012)
Human High Temperature Requirement Serine Protease A1 (HTRA1) Degrades Tau Protein Aggregates. Journal of Biological Chemistry 19.
Journal Article
13 (3), pp. 402 - 408 (2012)
Chemical Biology Approaches Reveal Conserved Features of a C-Terminal Processing PDZ Protease. ChemBioChem 20.
Journal Article
134 (1), pp. 103 - 106 (2012)
Structure of the Stapled p53 Peptide Bound to Mdm2. Journal of the American Chemical Society