Publications of Georg H. H. Borner

Ravenhill, B. J.; Oliveira, M.; Wood, G.; Di, Y.; Kite, J.; Wang, X.; Davies, C. T. R.; Lu, Y.; Antrobus, R.; Elliott, G. et al.; Irigoyen, N.; Hughes, D. J.; Lyons, P. A.; Chung, B.; Borner, G. H. H.; Weekes, M. P.: Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11. Cell Reports 44 (2), 115263 (2025)

Wogram, E.; Sümpelmann, F.; Dong, W.; Rawat, E.; Fernández Maestre, I.; Fu, D.; Braswell, B.; Khalil, A.; Buescher, J. M.; Mittler, G. et al.; Borner, G. H. H.; Vlachos, A.; Tholen, S.; Schilling, O.; Bell, G. W.; Rambold, A. S.; Akhtar, A.; Schnell, O.; Beck, J.; Abu-Remaileh, M.; Prinz, M.; Jaenisch, R.: Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes. Immunity 57 (9), pp. 2216 - 2231 (2024)

Saffari, A.; Brechmann, B.; Böger, C.; Saber, W. A.; Jumo, H.; Whye, D.; Wood, D.; Wahlster, L.; Alecu, J. E.; Ziegler, M. et al.; Scheffold, M.; Winden, K.; Hubbs, J.; Buttermore, E. D.; Barrett, L.; Borner, G. H. H.; Davies, A. K.; Ebrahimi-Fakhari, D.; Sahin, M.: High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia. Nature Communications 15, 584 (2024)

Schessner, J. P.; Albrecht, V.; Davies, A. K.; Sinitcyn, P.; Borner, G. H. H.: Deep and fast label-free Dynamic Organellar Mapping. Nature Communications 14 (1), 5252 (2023)

Rodriguez-Silvestre, P.; Laub, M.; Krawczyk, P. A.; Davies, A. K.; Schessner, J. P.; Parveen, R.; Tuck, B. J.; McEwan, W. A.; Borner, G. H.; Kozik, P.: Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells. Science 380 (6651), pp. 1258 - 1265 (2023)

O'Neill, A. C.; Uzbas, F.; Antognolli, G.; Merino, F.; Draganova, K.; Jaeck, A.; Zhang, S.; Pedini, G.; Schessner, J. P.; Cramer, K. et al.; Schepers, A.; Metzger, F.; Esgleas, M.; Smialowski, P.; Guerrini, R.; Falk, S.; Feederle, R.; Freytag, S.; Wang, Z.; Bahlo, M.; Jungmann, R.; Bagni, C.; Borner, G. H. H.; Robertson, S. P.; Hauck, S. M.; Goetz, M.: Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity. Science 376 (6599), eabf9088 (2022)

Davies, A. K.; Alecu, J. E.; Ziegler, M.; Vasilopoulou, C. G.; Merciai, F.; Jumo, H.; Afshar-Saber, W.; Sahin, M.; Ebrahimi-Fakhari, D.; Borner, G. H. H.: AP-4-mediated axonal transport controls endocannabinoid production in neurons. Nature Communications 13 (1), 1058 (2022)

Martin-Jaular, L.; Nevo, N.; Schessner, J. P.; Tkach, M.; Jouve, M.; Dingli, F.; Loew, D.; Witwer, K. W.; Ostrowski, M.; Borner, G. H. H. et al.; Thery, C.: Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV-1 infection. EMBO Journal 40, e105492 (2021)

Borner, G. H. H.: Spatial Proteomics: A Gateway to Understanding Cell Biology. Proteomics 20 (23, SI), 1900328 (2020)

Behne, R.; Teinert, J.; Wimmer, M.; D'Amore, A.; Davies, A. K.; Scarrott, J. M.; Eberhardt, K.; Brechmann, B.; Chen, I. P.-F.; Buttermore, E. D. et al.; Barrett, L.; Dwyer, S.; Chen, T.; Hirst, J.; Wiesener, A.; Segal, D.; Martinuzzi, A.; Duarte, S. T.; Bennett, J. T.; Bourinaris, T.; Houlden, H.; Roubertie, A.; Santorelli, F. M.; Robinson, M.; Azzouz, M.; Lipton, J. O.; Borner, G. H. H.; Sahin, M.; Ebrahimi-Fakhari, D.: Adaptor protein complex 4 deficiency: a paradigm of childhood-onset hereditary spastic paraplegia caused by defective protein trafficking. HUMAN MOLECULAR GENETICS 29 (2), pp. 320 - 334 (2020)

Borner, G. H. H.: Organellar Maps Through Proteomic Profiling - A Conceptual Guide. Molecular and Cellular Proteomics 19 (7), pp. 1076 - 1087 (2020)

Kozik, P.; Gros, M.; Itzhak, D. N.; Joannas, L.; Heurtebise-Chretien, S.; Krawczyk, P. A.; Rodriguez-Silvestre, P.; Alloatti, A.; Magalhaes, J. G.; Del Nery, E. et al.; Borner, G. H. H.; Amigorena, S.: Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity. CELL REPORTS 32 (2), 107905 (2020)

Yu, S.-H.; Ferretti, D.; Schessner, J. P.; Rudolph, J. D.; Borner, G. H. H.; Cox, J.: Expanding the Perseus Software for Omics Data Analysis With Custom Plugins. Current protocols in bioinformatics 71 (1), e105 (2020)

Lundberg, E.; Borner, G. H. H.: Spatial proteomics: a powerful discovery tool for cell biology. Nature Reviews Molecular Cell Biology 20 (5), pp. 285 - 302 (2019)

Schmidt, R. M.; Schessner, J. P.; Borner, G.; Schuck, S.: The proteasome biogenesis regulator Rpn4 cooperates with the unfolded protein response to promote ER stress resistance. eLife 8, e43244 (2019)

Nahorski, M. S.; Borner, G. H. H.; Shaikh, S. S.; Davies, A. K.; Al-Gazali, L.; Antrobus, R.; Woods, C. G.: Clathrin heavy chain 22 contributes to the control of neuropeptide degradation and secretion during neuronal development. Scientific Reports 8, 2340 (2018)

Hirst, J.; Itzhak, D. N.; Antrobus, R.; Borner, G. H. H.; Robinson, M. S.: Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval. PLoS Biology 16 (1), e2004411 (2018)

Davies, A. K.; Itzhak, D. N.; Edgar, J. R.; Archuleta, T. L.; Hirst, J.; Jackson, L. P.; Robinson, M. S.; Borner, G. H. H.: AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A. Nature Communications 9, 3958 (2018)

Itzhak, D. N.; Schessner, J. P.; Borner, G. H. H.: Dynamic Organellar Maps for Spatial Proteomics. Current protocols in cell biology, e81 (2018)

Krahmer, N.; Najafi, B.; Schueder, F.; Quagliarini, F.; Steger, M.; Seitz, S.; Kasper, R.; Salinas, F.; Cox, J.; Uhlenhaut, N. H. et al.; Walther, T. C.; Jungmann, R.; Zeigerer, A.; Borner, G. H. H.; Mann, M.: Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis. Developmental Cell 47 (2), pp. 205 - 221.e7 (2018)