Publications of R. Huber

Declerck, N.; Machius, M.; Joyet, P.; Wiegand, G.; Huber, R.; Gaillardin, C.: Hyperthermostabilization of Bacillus licheniformis α-amylase and modulation of its stability over a 50 degrees C temperature range. Protein Engineering 16 (4), pp. 287 - 293 (2003)

Machius, M.; Declerck, N.; Huber, R.; Wiegand, G.: Kinetic stabilization of Bacillus licheniformis alpha-amylase through introduction of hydrophobic residues at the surface. Journal of Biological Chemistry 278 (13), pp. 11546 - 11553 (2003)

Peng, G. H.; Fritzsch, G.; Zickermann, V.; Schaagger, H.; Mentele, R.; Lottspeich, F.; Bostina, M.; Radermacher, M.; Huber, R.; Stetter, K. O. et al.; Michel, H.: Isolation, characterization and electron microscopic single particle analysis of the NADH: ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium Aquifex aeolicus. Biochemistry 42 (10), pp. 3032 - 3039 (2003)

Groll, M.; Brandstetter, H.; Bartunik, H.; Bourenkow, G.; Huber, R.: Investigations on the maturation and regulation of archaebacterial proteasomes. Journal of Molecular Biology 327 (1), pp. 75 - 83 (2003)

Steinbacher, S.; Hernandez-Acosta, P.; Bieseler, B.; Blaesse, M.; Huber, R.; Culianez-Macia, F. A.; Kupke, T.: Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate. Journal of Molecular Biology 327 (1), pp. 193 - 202 (2003)

Bauer, S.; Kemter, K.; Bacher, A.; Huber, R.; Fischer, M.; Steinbacher, S.: Crystal structure of Schizosaccharomyces pombe riboflavin kinase reveals a novel ATP and riboflavin-binding fold. Journal of Molecular Biology 326 (5), pp. 1463 - 1473 (2003)

Dobbek, H.; Huber, R.: Aerobic and anaerobic life on carbon monoxide. Abstracts of Papers of the American Chemical Society 225, p. U56 - U56 (2003)

Messerschmidt, A.; Worbs, M.; Steegborn, C.; Wahl, M. C.; Huber, R.; Laber, B.; Clausen, T.: Determinants of enzymatic specificity in the Cys-Met-metabolism PLP-dependent enzyme family: Crystal structure of cystathionine γ-lyase from yeast and intrafamiliar structure comparison. Biological Chemistry 384 (3), pp. 373 - 386 (2003)

Fischer, M.; Haase, I.; Kis, K.; Meining, W.; Ladenstein, R.; Cushman, M.; Schramek, N.; Huber, R.; Bacher, A.: Enzyme catalysis via control of activation entropy: Site-directed mutagenesis of 6,7-dimethyl-8-ribityl-lumazine synthase. Journal of Molecular Biology 326 (3), pp. 783 - 793 (2003)

Rebelo, J.; Auerbach, G.; Bader, G.; Bracher, A.; Nar, H.; Hösl, C.; Schramek, N.; Kaiser, J.; Bacher, A.; Huber, R. et al.; Fischer, M.: Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I. Journal of Molecular Biology 326 (2), pp. 503 - 516 (2003)

Sichler, K.; Kopetzki, E.; Huber, R.; Bode, W.; Hopfner, K. P.; Brandstetter, H.: Physiological fIXa activation involves a cooperative conformational rearrangement of the 99-loop. Journal of Biological Chemistry 278 (6), pp. 4121 - 4126 (2003)

Krapp, S.; Mimura, Y.; Jefferis, R.; Huber, R.; Sondermann, P.: Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity. Journal of Molecular Biology 325 (5), pp. 979 - 989 (2003)

Kaiser, J. T.; Bruno, S.; Clausen, T.; Huber, R.; Schiaretti, F.; Mozzarelli, A.; Kessler, D.: Snapshots of the cystine lyase C-DES during catalysis - Studies in solution and in the crystalline state. Journal of Biological Chemistry 278 (1), pp. 357 - 365 (2003)

Fischer, M. J.; Schott, A. K.; Kemter, K.; Feicht, R.; Richter, G.; Illarionov, B.; Eisenreich, W.; Gerhardt, S.; Cushman, M.; Steinbacher, S. et al.; Huber, R.; Bacher, A.: Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by ¹⁹F NMR protein perturbation experiments. BMC Biochemistry 4 (1), 18, pp. [1] - [19] (2003)

Kaiser, M.; Milbradt, A. G.; Renner, C.; Assfalg-Machleidt, I.; Groll, M.; Huber, R.; Moroder, L.: Cyclic biphenyl ether tripeptides as proteasome inhibitors. Biopolymers 71 (3), p. 396 - 396 (2003)

Song, H. K.; Bochtler, M.; Azim, M. K.; Hartmann, C.; Huber, R.; Ramachandran, R.: Isolation and characterization of the prokaryotic proteasome homolog HslVU (ClpQY) from Thermotoga maritima and the crystal structure of HslV. Biophysical Chemistry 100 (1-3 Sp. Iss. SI), pp. 437 - 452 (2003)

Kim, J. S.; Groll, M.; Musiol, H.-J.; Behrendt, R.; Kaiser, M.; Moroder, L.; Huber, R.; Brandstetter, H.: Navigation inside a protease: Substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum. Journal of Molecular Biology 324 (5), pp. 1041 - 1050 (2002)

Dobbek, H.; Gremer, L.; Kiefersauer, R.; Huber, R.; Meyer, O.: Catalysis at a dinuclear [CuSMo(==O)OH] cluster in a CO dehydrogenase resolved at 1.1-angstrom resolution. Proceedings of the National Academy of Sciences of the United States of America 99 (25), pp. 15971 - 15976 (2002)

Rehm, T.; Huber, R.; Holak, T. A.: Application of NMR in structural proteomics: Screening for proteins amenable to structural analysis. Structure 10 (12), pp. 1613 - 1618 (2002)

Fischer, M.; Römisch, W.; Schiffmann, S.; Kelly, M.; Oschkinat, H.; Steinbacher, S.; Huber, R.; Eisenreich, W.; Richter, G.; Bacher, A.: Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii. Journal of Biological Chemistry 277 (44), pp. 41410 - 41416 (2002)