Emmy-Noether-Research Group "DNA Hybridnanomaterials"
DNA Nanotechnology, DNA-Silica Hybridnanomaterials, Bionanotechnology, Biophysics
DNA nanotechnology allows for the fabrication of nanometer-sized objects with high precision and selective addressability due to the programmable hybridization of complementary DNA strands. Especially the introduction of the DNA origami technique has resulted in a plethora of objects of different shapes, sizes and complexities with subnanometer precision feature control. DNA origami structures can be assembled with a great number of site-specific and chemically distinct functionalities and ligands. One of our research interests is to use DNA Origami nanostructures to decipher complex cellular signalling cascades and to investigate the interactions of DNA origami-templated silica nanostructures with cells for possible biomedical applications and the creation of highly efficient enzyme cascades.