Selected Publications

Journal Article (59)

1.
Journal Article
Voll, A. M.; Meyners, C.; Taubert, M. C.; Bajaj, T.; Heymann, T.; Merz, S.; Charalampidou, A.; Kolos, J.; Purder, P. L.; Geiger, T. M. et al.; Wessig, P.; Gassen, N. C.; Bracher, A.; Hausch, F.: Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity. Angewandte Chemie International Edition 60, pp. 2 - 9 (2021)
2.
Journal Article
Zinzula, L.; Basquin, J.; Bohn, S.; Beck, F.; Klumpe, S.; Pfeifer, G.; Nagy, I.; Bracher, A.; Hartl, F. U.; Baumeister, W.: High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2 acute respiratory syndrome coronavirus 2. Biochemical and Biophysical Research Communications 538, pp. 54 - 62 (2021)
3.
Journal Article
Flecken, M.; Wang, H.; Popilka, L.; Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes. Cell 183 (2), pp. 457 - 473.e20 (2020)
4.
Journal Article
Bracher, A.; Paul, S. S.; Wang, H.; Wischnewski, N.; Hartl, F. U.; Hayer-Hartl, M.: Structure and conformational cycle of a bacteriophage-encoded chaperonin. PLOS ONE 15 (4), e0230090 (2020)
5.
Journal Article
Mönkemeyer, L.; Klaips, C. L.; Balchin, D.; Körner, R.; Hartl, F. U.; Bracher, A.: Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2. Molecular Cell 74 (1), pp. 88 - 100.e9 (2019)
6.
Journal Article
Wang, H.; Yan, X.; Aigner, H.; Bracher, A.; Nguyen, N. D.; Hee, W. Y.; Long, B. M.; Price, G. D.; Hartl, F. U.; Hayer-Hartl, M.: Rubisco condensate formation by CcmM in beta-carboxysome biogenesis. Nature 566 (7742), pp. 131 - 135 (2019)
7.
Journal Article
Wilson, R. H.; Hayer-Hartl, M.; Bracher, A.: Crystal structure of phosphoribulokinase from Synechococcus sp. strain PCC 6301. Acta Crystallographica Section F: Structural Biology Communications 75 (4), pp. 278 - 289 (2019)
8.
Journal Article
Zinzula, L.; Nagy, I.; Orsini, M.; Weyher-Stingl, E.; Bracher, A.; Baumeister, W.: Structures of Ebola and Reston Virus VP35 Oligomerization Domains and Comparative Biophysical Characterization in All Ebolavirus Species. Structure 27 (1), pp. 39 - 54.e6 (2019)
9.
Journal Article
Pomplun, S.; Sippel, C.; Haehle, A.; Tay, D.; Shima, K.; Klages, A.; Uenal, C. M.; Riess, B.; Toh, H. T.; Hansen, G. et al.; Yoon, H. S.; Bracher, A.; Preiser, P.; Rupp, J.; Steinert, M.; Hausch, F.: Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins. Journal of Medicinal Chemistry 61 (8), pp. 3660 - 3673 (2018)
10.
Journal Article
Yan, X.; Shi, Q.; Bracher, A.; Milicic, G.; Singh, A. K.; Hartl, F. U.; Hayer-Hartl, M.: GroEL Ring Separation and Exchange in the Chaperonin Reaction. Cell 172 (3), pp. 605 - 617.e11 (2018)
11.
Journal Article
Aigner, H.; Wilson, R. H.; Bracher, A.; Calisse, L.; Bhat, J. Y.; Hartl, F. U.; Hayer-Hartl, M.: Plant RuBisCo assembly in E. coli with five chloroplast chaperones including BSD2. Science 358 (6368), pp. 1272 - 1278 (2017)
12.
Journal Article
Bhat, J. Y.; Milicic, G.; Thieulin-Pardo, G.; Bracher, A.; Maxwell, A.; Ciniawsky, S.; Mueller-Cajar, O.; Engen, J. R.; Hartl, F. U.; Wendler, P. et al.; Hayer-Hartl, M.: Mechanism of Enzyme Repair by the AAA(+) Chaperone Rubisco Activase. Molecular Cell 67 (5), pp. 744 - 756.e6 (2017)
13.
Journal Article
Pathare, G. R.; Nagy, I.; Hubert, A.; Thomas, D. R.; Bracher, A.: Crystal structure of the Thermoplasma acidophilum protein Ta1207. Acta Crystallographica Section F: Structural Biology Communications 73, pp. 328 - 335 (2017)
14.
Journal Article
Gaali, S.; Feng, X.; Haehle, A.; Sippel, C.; Bracher, A.; Hausch, F.: Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51. JOURNAL OF MEDICINAL CHEMISTRY 59 (6), pp. 2410 - 2422 (2016)
15.
Journal Article
Hayer-Hartl, M.; Bracher, A.; Hartl, F. U.: The GroEL-GroES Chaperonin Machine: A Nano-Cage for Protein Folding. Trends in Biochemical Sciences: TIBS / International Union of Biochemistry and Molecular Biology. 41 (1; Special Issue: 40 Years of TiBS), pp. 62 - 76 (2016)
16.
Journal Article
Neudegger, T.; Verghese, J.; Hayer-Hartl, M.; Hartl, F. U.; Bracher, A.: Structure of human heat-shock transcription factor 1 in complex with DNA. NATURE STRUCTURAL & MOLECULAR BIOLOGY 23 (2), pp. 140 - 146 (2016)
17.
Journal Article
Bracher, A.; Hauser, T.; Liu, C.; Hartl, F. U.; Hayer-Hartl, M.: Structural Analysis of the Rubisco-Assembly Chaperone RbcX-II from Chlamydomonas reinhardtii. PLOS ONE 10 (8), e0135448 (2015)
18.
Journal Article
Bracher, A.; Sharma, A.; Starling-Windhof, A.; Hartl, F. U.; Hayer-Hartl, M.: Degradation of potent Rubisco inhibitor by selective sugar phosphatase. NATURE PLANTS 1 (1), 14002 (2015)
19.
Journal Article
Bracher, A.; Verghese, J.: The nucleotide exchange factors of Hsp70 molecular chaperones. Frontiers in molecular biosciences 2, 10, pp. 1 - 9 (2015)
20.
Journal Article
Feng, X.; Sippel, C.; Bracher, A.; Hausch, F.: Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands. JOURNAL OF MEDICINAL CHEMISTRY 58 (19), pp. 7796 - 7806 (2015)
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