Selected Publications

Kolos, J. M.; Pomplun, S.; Jung, S.; Riess, B.; Purder, P. L.; Voll, A. M.; Merz, S.; Gnatzy, M.; Geiger, T. M.; Quist-Lokken, I. et al.; Jatzlau, J.; Knaus, P.; Holien, T.; Bracher, A.; Meyners, C.; Czodrowski, P.; Krewald, V.; Hausch, F.: Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides. Chemical Science 12 (44), pp. 14758 - 14765 (2021)

Schneider, M. M.; Gautam, S.; Herling, T. W.; Andrzejewska, E.; Krainer, G.; Miller, A. M.; Trinkaus, V. A.; Peter, Q. A. E.; Ruggeri, F. S.; Vendruscolo, M. et al.; Bracher, A.; Dobson, C. M.; Hartl, F. U.; Knowles, T. P. J.: The Hsc70 disaggregation machinery removes monomer units directly from alpha-synuclein fibril ends. Nature Communications 12 (1), 5999 (2021)

Voll, A. M.; Meyners, C.; Taubert, M. C.; Bajaj, T.; Heymann, T.; Merz, S.; Charalampidou, A.; Kolos, J.; Purder, P. L.; Geiger, T. M. et al.; Wessig, P.; Gassen, N. C.; Bracher, A.; Hausch, F.: Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity. Angewandte Chemie International Edition 60, pp. 2 - 9 (2021)

Yuste-Checa, P.; Trinkaus, V. A.; Riera-Tur, I.; Imamoglu, R.; Schaller, T. F.; Wang, H.; Dudanova, I.; Hipp, M. S.; Bracher, A.; Hartl, F. U.: The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model. Nature Communications 12 (1), 4863 (2021)

Zinzula, L.; Basquin, J.; Bohn, S.; Beck, F.; Klumpe, S.; Pfeifer, G.; Nagy, I.; Bracher, A.; Hartl, F. U.; Baumeister, W.: High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2 acute respiratory syndrome coronavirus 2. Biochemical and Biophysical Research Communications 538, pp. 54 - 62 (2021)