Publications of R. Huber

Cunha, C. A.; Macieira, S.; Dias, J. M.; Almeida, G.; Goncalves, L. L.; Costa, C.; Lampreia, J.; Huber, R.; Moura, J. J. G.; Moura, I. et al.; Romao, M. J.: Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774 - The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA). Journal of Biological Chemistry 278 (19), pp. 17455 - 17465 (2003)

Groll, M.; Huber, R.: Substrate access and processing by the 20S proteasome core particle. International Journal of Biochemistry & Cell Biology 35 (5), pp. 606 - 616 (2003)

Engel, M.; Hoffmann, T.; Wagner, L.; Wermann, M.; Heiser, U.; Kiefersauer, R.; Huber, R.; Bode, W.; Demuth, H. U.; Brandstetter, H.: The crystal structure of dipeptidyl peptidase IV(CD26) reveals its functional regulation and enzymatic mechanism. Proceedings of the National Academy of Sciences of the United States of America 100 (9), pp. 5063 - 5068 (2003)

Declerck, N.; Machius, M.; Joyet, P.; Wiegand, G.; Huber, R.; Gaillardin, C.: Hyperthermostabilization of Bacillus licheniformis α-amylase and modulation of its stability over a 50 degrees C temperature range. Protein Engineering 16 (4), pp. 287 - 293 (2003)

Machius, M.; Declerck, N.; Huber, R.; Wiegand, G.: Kinetic stabilization of Bacillus licheniformis alpha-amylase through introduction of hydrophobic residues at the surface. Journal of Biological Chemistry 278 (13), pp. 11546 - 11553 (2003)

Peng, G. H.; Fritzsch, G.; Zickermann, V.; Schaagger, H.; Mentele, R.; Lottspeich, F.; Bostina, M.; Radermacher, M.; Huber, R.; Stetter, K. O. et al.; Michel, H.: Isolation, characterization and electron microscopic single particle analysis of the NADH: ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium Aquifex aeolicus. Biochemistry 42 (10), pp. 3032 - 3039 (2003)

Groll, M.; Brandstetter, H.; Bartunik, H.; Bourenkow, G.; Huber, R.: Investigations on the maturation and regulation of archaebacterial proteasomes. Journal of Molecular Biology 327 (1), pp. 75 - 83 (2003)

Steinbacher, S.; Hernandez-Acosta, P.; Bieseler, B.; Blaesse, M.; Huber, R.; Culianez-Macia, F. A.; Kupke, T.: Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate. Journal of Molecular Biology 327 (1), pp. 193 - 202 (2003)

Bauer, S.; Kemter, K.; Bacher, A.; Huber, R.; Fischer, M.; Steinbacher, S.: Crystal structure of Schizosaccharomyces pombe riboflavin kinase reveals a novel ATP and riboflavin-binding fold. Journal of Molecular Biology 326 (5), pp. 1463 - 1473 (2003)

Dobbek, H.; Huber, R.: Aerobic and anaerobic life on carbon monoxide. Abstracts of Papers of the American Chemical Society 225, p. U56 - U56 (2003)

Messerschmidt, A.; Worbs, M.; Steegborn, C.; Wahl, M. C.; Huber, R.; Laber, B.; Clausen, T.: Determinants of enzymatic specificity in the Cys-Met-metabolism PLP-dependent enzyme family: Crystal structure of cystathionine γ-lyase from yeast and intrafamiliar structure comparison. Biological Chemistry 384 (3), pp. 373 - 386 (2003)

Fischer, M.; Haase, I.; Kis, K.; Meining, W.; Ladenstein, R.; Cushman, M.; Schramek, N.; Huber, R.; Bacher, A.: Enzyme catalysis via control of activation entropy: Site-directed mutagenesis of 6,7-dimethyl-8-ribityl-lumazine synthase. Journal of Molecular Biology 326 (3), pp. 783 - 793 (2003)

Rebelo, J.; Auerbach, G.; Bader, G.; Bracher, A.; Nar, H.; Hösl, C.; Schramek, N.; Kaiser, J.; Bacher, A.; Huber, R. et al.; Fischer, M.: Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I. Journal of Molecular Biology 326 (2), pp. 503 - 516 (2003)

Sichler, K.; Kopetzki, E.; Huber, R.; Bode, W.; Hopfner, K. P.; Brandstetter, H.: Physiological fIXa activation involves a cooperative conformational rearrangement of the 99-loop. Journal of Biological Chemistry 278 (6), pp. 4121 - 4126 (2003)

Krapp, S.; Mimura, Y.; Jefferis, R.; Huber, R.; Sondermann, P.: Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity. Journal of Molecular Biology 325 (5), pp. 979 - 989 (2003)

Kaiser, J. T.; Bruno, S.; Clausen, T.; Huber, R.; Schiaretti, F.; Mozzarelli, A.; Kessler, D.: Snapshots of the cystine lyase C-DES during catalysis - Studies in solution and in the crystalline state. Journal of Biological Chemistry 278 (1), pp. 357 - 365 (2003)

Fischer, M. J.; Schott, A. K.; Kemter, K.; Feicht, R.; Richter, G.; Illarionov, B.; Eisenreich, W.; Gerhardt, S.; Cushman, M.; Steinbacher, S. et al.; Huber, R.; Bacher, A.: Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by ¹⁹F NMR protein perturbation experiments. BMC Biochemistry 4 (1), 18, pp. [1] - [19] (2003)

Kaiser, M.; Milbradt, A. G.; Renner, C.; Assfalg-Machleidt, I.; Groll, M.; Huber, R.; Moroder, L.: Cyclic biphenyl ether tripeptides as proteasome inhibitors. Biopolymers 71 (3), p. 396 - 396 (2003)

Song, H. K.; Bochtler, M.; Azim, M. K.; Hartmann, C.; Huber, R.; Ramachandran, R.: Isolation and characterization of the prokaryotic proteasome homolog HslVU (ClpQY) from Thermotoga maritima and the crystal structure of HslV. Biophysical Chemistry 100 (1-3 Sp. Iss. SI), pp. 437 - 452 (2003)

Kim, J. S.; Groll, M.; Musiol, H.-J.; Behrendt, R.; Kaiser, M.; Moroder, L.; Huber, R.; Brandstetter, H.: Navigation inside a protease: Substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum. Journal of Molecular Biology 324 (5), pp. 1041 - 1050 (2002)