Publications of R. Huber

Than, M. E.; Helm, M.; Simpson, D. J.; Lottspeich, F.; Huber, R.; Gietl, C.: The 2.0 angstrom crystal structure and substrate specificity of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm. Journal of Molecular Biology 336 (5), pp. 1103 - 1116 (2004)

Kim, J. S.; Kluskens, L. D.; de Vos, W. M.; Huber, R.; van der Oost, J.: Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin. Journal of Molecular Biology 335 (3), pp. 787 - 797 (2004)

Svetlitchnyi, V.; Dobbek, H.; Meyer-Klaucke, W.; Meins, T.; Thiele, B.; Römer, P.; Huber, R.; Meyer, O.: A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans. Proceedings of the National Academy of Sciences of the United States of America 101 (2), pp. 446 - 451 (2004)

Krapp, S.; Munster-Kuhnel, A. K.; Kaiser, J. T.; Huber, R.; Tiralongo, J.; Gerardy-Schahn, R.; Jacob, U.: The crystal structure of murine CMP-5-N-acetylneuraminic acid synthetase. Journal of Molecular Biology 334 (4), pp. 625 - 637 (2003)

Breitenlechner, C.; Gassel, M.; Hidaka, H.; Kinzel, V.; Huber, R.; Engh, R. A.; Bossemeyer, D.: Protein kinase a in complex with rho-kinase inhibitors Y-27632, fasudil, and H-1152P: Structural basis of selectivity. Structure 11 (12), pp. 1595 - 1607 (2003)

Steinbacher, S.; Schiffmann, S.; Richter, G.; Huber, R.; Bacher, A.; Fischer, M.: Structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with divalent metal ions and the substrate ribulose 5-phosphate - Implications for the catalytic mechanism. Journal of Biological Chemistry 278 (43), pp. 42256 - 42265 (2003)

Friedrich, R.; Panizzi, P.; Fuentes-Prior, P.; Richter, K.; Verhamme, I.; Anderson, P. J.; Kawabata, S. I.; Huber, R.; Bode, W.; Bock, P. E.: Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation. Nature 425 (6957), pp. 535 - 539 (2003)

Almeida, M. G.; Macieira, S.; Goncalves, L. L.; Huber, R.; Cunha, C. A.; Romao, M. J.; Costa, C.; Lampreia, J.; Moura, J. J. G.; Moura, I.: The isolation and characterization of cytochrome c nitrite reductase subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774 - Re-evaluation of the spectroscopic data and redox properties. European Journal of Biochemistry 270 (19), pp. 3904 - 3915 (2003)

Macieira, S.; Martins, B. M.; Huber, R.: Oxygen-dependent coproporphyrinogen-III oxidase from Escherichia coli: one-step purification and biochemical characterisation. FEMS Microbiology Letters 226 (1), pp. 31 - 37 (2003)

Jozic, D.; Kaiser, J. T.; Huber, R.; Bode, W.; Maskos, K.: X-ray structure of isoaspartyl dipeptidase from E-coli: A dinuclear zinc peptidase evolved from amidohydrolases. Journal of Molecular Biology 332 (1), pp. 243 - 256 (2003)

Breithaupt, C.; Schubart, A.; Zander, H.; Skerra, A.; Huber, R.; Linington, C.; Jacob, U.: Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein. Proceedings of the National Academy of Sciences of the United States of America 100 (16), pp. 9446 - 9451 (2003)

Blaesse, M.; Kupke, T.; Huber, R.; Steinbacher, S.: Structure of MrsD, an FAD-binding protein of the HFCD family. Acta Crystallographica Section D-Biological Crystallography 59, pp. 1414 - 1421 (2003)

Gerhardt, S.; Echt, S.; Busch, M.; Freigang, J.; Auerbach, G.; Bader, G.; Martin, W. F.; Bacher, A.; Huber, R.; Fischer, M.: Structure and properties of an engineered transketolase from maize. Plant Physiology 132 (4), pp. 1941 - 1949 (2003)

Wendt, K. S.; Schall, I.; Huber, R.; Buckel, W.; Jacob, U.: Crystal structure of the carboxyltransferase subunit of the bacterial sodium ion pump glutaconyl-coenzyme A decarboxylase. EMBO Journal 22 (14), pp. 3493 - 3502 (2003)

Henrich, S.; Cameron, A.; Bourenkov, G. P.; Kiefersauer, R.; Huber, R.; Lindberg, I.; Bode, W.; Than, M. E.: The crystal structure of the proprotein processing proteinase furin explains its stringent specificity. Nature Structural Biology 10 (7), pp. 520 - 526 (2003)

Gassel, M.; Breitenlechner, C. B.; Ruger, P.; Jucknischke, U.; Schneider, T.; Huber, R.; Bossemeyer, D.; Engh, R. A.: Mutants of protein kinase a that mimic the ATP-binding site of protein kinase B (AKT). Journal of Molecular Biology 329 (5), pp. 1021 - 1034 (2003)

Steinbacher, S.; Kaiser, J.; Gerhardt, S.; Eisenreich, W.; Huber, R.; Bacher, A.; Rohdich, F.: Crystal structure of the type II isopentenyl diphosphate: Dimethylallyl diphosphate isomerase from Bacillus subtilis. Journal of Molecular Biology 329 (5), pp. 973 - 982 (2003)

Augustin, M. A.; Reichert, A. S.; Betat, H.; Huber, R.; Morl, M.; Steegborn, C.: Crystal structure of the human CCA-adding enzyme: Insights into template-independent polymerization. Journal of Molecular Biology 328 (5), pp. 985 - 994 (2003)

Bae, J. H.; Rubini, M.; Jung, G.; Wiegand, G.; Seifert, M. H. J.; Azim, M. K.; Kim, J. S.; Zumbusch, A.; Holak, T. A.; Moroder, L. et al.; Huber, R.; Budisa, N.: Expansion of the genetic code enables design of a novel "gold'' class of green fluorescent proteins. Journal of Molecular Biology 328 (5), pp. 1071 - 1081 (2003)

Steinbacher, S.; Kaiser, J.; Eisenreich, W.; Huber, R.; Bacher, A.; Rohdich, F.: Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC) - Implications for the catalytic mechanism and anti-malaria drug development. Journal of Biological Chemistry 278 (20), pp. 18401 - 18407 (2003)