Publications of R. Huber

Stanitzek, S.; Augustin, M. A.; Huber, R.; Kupke, T.; Steinbacher, S.: Structural basis of CTP-dependent peptide bond formation in coenzyme A biosynthesis catalyzed by Escherichia coli PPC synthetase. Structure 12 (11), pp. 1977 - 1988 (2004)

Fischer, M.; Schott, A. K.; Romisch, W.; Ramsperger, A.; Augustin, M.; Fidler, A.; Bacher, A.; Richter, G.; Huber, R.; Eisenreich, W.: Evolution of vitamin B-2 biosynthesis. A novel class of riboflavin synthase in Archaea. Journal of Molecular Biology 343 (1), pp. 267 - 278 (2004)

Popowicz, G. M.; Muller, R.; Noegel, A. A.; Schleicher, M.; Huber, R.; Holak, T. A.: Molecular structure of the rod domain of Dictyostelium filamin. Journal of Molecular Biology 342 (5), pp. 1637 - 1646 (2004)

Bonin, I.; Muhlberger, R.; Bourenkov, G. P.; Huber, R.; Bacher, A.; Richter, G.; Wahl, M. C.: Structural basis for the interaction of Escherichia coli NusA with protein N of phage lambda. Proceedings of the National Academy of Sciences of the United States of America 101 (38), pp. 13762 - 13767 (2004)

Kaiser, M.; Groll, M.; Siciliano, C.; Assfalg-Machleidt, I.; Weyher, E.; Kohno, J.; Milbradt, A. G.; Renner, C.; Huber, R.; Moroder, L.: Binding mode of TMC-95A analogues to eukaryotic 20S proteasome. ChemBioChem 5 (9), pp. 1256 - 1266 (2004)

Breithaupt, C.; Schubart, A.; Zander, H.; Skerra, A.; Linington, C.; Huber, R.; Jacob, U.: Structural insights into the multiple sclerosis autoantigen myelin oligodendrocyte glycoprotein and its complex with a pathogenic autoantibody. Journal of Neuroimmunology 154 (1-2 Sp. Iss. Sp. Iss. SI), p. 94 - 94 (2004)

Keil, C.; Huber, R.; Bode, W.; Than, M. E.: Cloning, expression, crystallization and initial crystallographic analysis of the C-terminal domain of the amyloid precursor protein APP. Acta Crystallographica Section D-Biological Crystallography 60, pp. 1614 - 1617 (2004)

Echt, S.; Bauer, S.; Steinbacher, S.; Huber, R.; Bacher, A.; Fischer, M.: Potential anti-infective targets in pathogenic yeasts: Structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans. Journal of Molecular Biology 341 (4), pp. 1085 - 1096 (2004)

Bonin, I.; Martins, B. M.; Purvanov, V.; Fetzner, S.; Huber, R.; Dobbek, H.: Active site geometry and substrate recognition of the molybdenum hydroxylase quinoline 2-oxidoreductase. Structure 12 (8), pp. 1425 - 1435 (2004)

Koch, M.; Breithaupt, C.; Gerhardt, S.; Weber, S.; Cushman, M.; Huber, R.; Bacher, A.; Fischer, M.: Structural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase. European Journal of Biochemistry 271 (15), pp. 3208 - 3214 (2004)

Comellas-Bigler, M.; Maskos, K.; Huber, R.; Oyama, H.; Oda, K.; Bode, W.: 1.2 angstrom crystal structure of the serine carboxyl proteinase pro-kumamolisin: Structure of an intact pro-subtilase. Structure 12 (7), pp. 1313 - 1323 (2004)

Laupitz, R.; Hecht, S.; Amslinger, S.; Zepeck, F.; Kaiser, J.; Richter, G.; Schramek, N.; Steinbacher, S.; Huber, R.; Arigoni, D. et al.; Bacher, A.; Eisenreich, W.; Rohdich, F.: Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. European Journal of Biochemistry 271 (13), pp. 2658 - 2669 (2004)

Breitenlechner, C.; Engh, R. A.; Huber, R.; Kinzel, V.; Bossemeyer, D.; Gassel, M.: The typically disordered n-terminus of PKA can fold as a helix and project the myristoylation site into solution. Biochemistry 43 (24), pp. 7743 - 7749 (2004)

Bauer, S.; Schott, A. K.; Illarionova, V.; Bacher, A.; Huber, R.; Fischer, M.: Biosynthesis of tetrahydrofolate in plants: Crystal structure of 7,8-dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class. Journal of Molecular Biology 339 (4), pp. 967 - 979 (2004)

Bader, G.; Gomez-Ortiz, M.; Haussmann, C.; Bacher, A.; Huber, R.; Fischer, M.: Structure of the molybdenum-cofactor biosynthesis protein MoaB of Escherichia coli. Acta Crystallographica Section D-Biological Crystallography 60, pp. 1068 - 1075 (2004)

Gassel, M.; Breitenlechner, C. B.; Konig, N.; Huber, R.; Engh, R. A.; Bossemeyer, D.: The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. Journal of Biological Chemistry 279 (22), pp. 23679 - 23690 (2004)

Bae, J. H.; Pal, P. P.; Moroder, L.; Huber, R.; Budisa, N.: Crystallographic evidence for isomeric chromophores in 3-fluorotyrosyl-green fluorescent protein. ChemBioChem 5 (5), pp. 720 - 722 (2004)

Koch, M.; Breithaupt, C.; Kiefersauer, R.; Freigang, J.; Huber, R.; Messerschmidt, A.: Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis. EMBO Journal 23 (8), pp. 1720 - 1728 (2004)

Fritze, I. M.; Linden, L.; Freigang, J.; Auerbach, G.; Huber, R.; Steinbacher, S.: The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase. Plant Physiology 134 (4), pp. 1388 - 1400 (2004)

Breitenlechner, C. B.; Wegge, T.; Berillon, L.; Graul, K.; Marzenell, M.; Friebe, W. G.; Thomas, U.; Schumacher, R.; Huber, R.; Engh, R. A. et al.; Masjost, B.: Structure-based optimization of novel azepane derivatives as PKB inhibitors. Journal of Medicinal Chemistry 47 (6), pp. 1375 - 1390 (2004)