Publications of Brenda A. Schulman

Wallace, I.; Baek, K.; Prabu, J. R.; Vollrath, R.; von Gronau, S.; Schulman, B. A.; Swatek, K. N.: Insights into the ISG15 transfer cascade by the UBE1L activating enzyme. Nature Communications 14 (1), 7970 (2023)

Henneberg, L. T.; Singh, J.; Duda, D. M.; Baek, K.; Yanishevski, D.; Murray, P. J.; Mann, M.; Sidhu, S. S.; Schulman, B. A.: Activity-based profiling of cullin-RING E3 networks by conformation-specific probes. Nature Chemical Biology 19, pp. 1513 - 1523 (2023)

Purser, N.; Tripathi-Giesgen, I.; Li, J.; Scott, D. C.; Horn-Ghetko, D.; Baek, K.; Schulman, B. A.; Alpi, A. F.; Kleiger, G.: Catalysis of non-canonical protein ubiquitylation by the ARIH1 ubiquitin ligase. Biochemical Journal 480 (22), pp. 1817 - 1831 (2023)

Hehl, L. A.; Schulman, B. A.: To be (in a transcriptional complex) or not to be (promoting UBR5 ubiquitylation): That is an answer to how degradation controls gene expression. Molecular Cell 83 (15), pp. 2616 - 2618 (2023)

Kraus, F.; Goodall, E. A.; Smith, I. R.; Jiang, Y.; Paoli, J. C.; Adolf, F.; Zhang, J.; Paulo, J. A.; Schulman, B. A.; Harper, J. W.: PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems. EMBO Reports 24 (8), e56399 (2023)

Berrocal, D. A. P. A.; Vishwanatha, T. M.; Horn-Ghetko, D.; Botsch, J. J.; Hehl, L. A.; Kostrhon, S.; Misra, M.; Dikic, I.; Geurink, P. P.; van Dam, H. et al.; Schulman, B. A.; Mulder, M. P. C.: A Pro-Fluorescent Ubiquitin-Based Probe to Monitor Cysteine-Based E3 Ligase Activity. Angewandte Chemie International Edition 62 (32), e202303319 (2023)

Gonzalez, A.; Covarrubias-Pinto, A.; Bhaskara, R. M.; Glogger, M.; Kuncha, S. K.; Xavier, A.; Seemann, E.; Misra, M.; Hoffmann, M. E.; Bräuning, B. et al.; Balakrishnan, A.; Qualmann, B.; Doetsch, V.; Schulman, B. A.; Kessels, M. M.; Huebner, C. A.; Heilemann, M.; Hummer, G.; Dikic, I.: Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum. Nature 618 (7964), pp. 394 - 401 (2023)

Baek, K.; Scott, D. C.; Henneberg, L. T.; King, M. T.; Mann, M.; Schulman, B. A.: Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell 186 (9), pp. 1895 - 1911 (2023)

Dikic, I.; Schulman, B. A.: An expanded lexicon for the ubiquitin code. Nature Reviews Molecular Cell Biology 24 (4), pp. 273 - 287 (2023)

Scott, D. C.; King, M. T.; Baek, K.; Gee, C. T.; Kalathur, R.; Li, J.; Purser, N.; Nourse, A.; Chai, S. C.; Vaithiyalingam, S. et al.; Chen, T.; Lee, R. E.; Elledge, S. J.; Kleiger, G.; Schulman, B. A.: E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Molecular Cell 83 (5), pp. 770 - 786 (2023)

Li, M.; Tripathi-Giesgen, I.; Schulman, B. A.; Baumeister, W.; Wilfling, F.: In situ snapshots along a mammalian selective autophagy pathway. Proceedings of the National Academy of Sciences of the United States of America 120 (12), e2221712120 (2023)

Nardone, C.; Palanski, B. A.; Scott, D. C.; Timms, R. T.; Barber, K. W.; Gu, X.; Mao, A.; Leng, Y.; Watson, E. V.; Schulman, B. A. et al.; Cole, P. A.; Elledge, S. J.: A central role for regulated protein stability in the control of TFE3 and MITF by nutrients. Molecular Cell 83 (1), pp. 57 - 73 (2023)

Suryo Rahmanto, A.; Blum, C. J.; Scalera, C.; Heidelberger, J. B.; Mesitov, M.; Horn-Ghetko, D.; Gräf, J. F.; Mikicic, I.; Hobrecht, R.; Orekhova, A. et al.; Ostermaier, M.; Ebersberger, S.; Möckel, M. M.; Krapoth, N.; Da Silva Fernandes, N.; Mizi, A.; Zhu, Y.; Chen, J.-X.; Choudhary, C.; Papantonis, A.; Ulrich, H. D.; Schulman, B. A.; König, J.; Beli, P.: K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution. Molecular Cell 83, pp. 4272 - 4289 (2023)

Sherpa, D.; Mueller, J.; Karayel, Ö.; Xu, P.; Yao, Y.; Chrustowicz, J.; Gottemukkala, K. V.; Baumann, C. A.; Gross, A.; Czarnecki, O. et al.; Zhang, W.; Gu, J.; Nilvebrant, J.; Sidhu, S. S.; Murray, P. J.; Mann, M.; Weiss, M. J.; Schulman, B. A.; Alpi, A. F.: Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation. eLife 11, e77937 (2022)

Bieber, A.; Capitanio, C.; Erdmann, P. S.; Fiedler, F.; Beck, F.; Lee, C.-W.; Li, D.; Hummer, G.; Schulman, B. A.; Baumeister, W. et al.; Wilfling, F.: In situ structural analysis reveals membrane shape transitions during autophagosome formation. Proceedings of the National Academy of Sciences of the United States of America 119 (39), e2209823119 (2022)

Hopf, L. V. M.; Baek, K.; Klügel, M.; von Gronau, S.; Xiong, Y.; Schulman, B. A.: Structure of CRL7(FBXW)(8) reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation. Nature Structural & Molecular Biology 29 (9), pp. 854 - 862 (2022)

Langlois, C. R.; Beier, V.; Karayel, O.; Chrustowicz, J.; Sherpa, D.; Mann, M.; Schulman, B. A.: A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters. EMBO Reports 23 (6), e53835 (2022)

Qiao, S.; Lee, C.-W.; Sherpa, D.; Chrustowicz, J.; Cheng, J. D.; Duennebacke, M.; Steigenberger, B.; Karayel, O.; Tung Vu, D.; Gronau, S. v. et al.; Mann, M.; Wilfling, F.; Schulman, B.: Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nature Communications 13 (1), 3041 (2022)

Bludau, I.; Willems, S.; Zeng, W.-F.; Strauss, M. T.; Hansen, F. M.; Tanzer, M. C.; Karayel, O.; Schulman, B. A.; Mann, M.: The structural context of posttranslational modifications at a proteome-wide scale. PLoS Biology 20 (5), e3001636 (2022)

Sherpa, D.; Chrustowicz, J.; Schulman, B.: How the ends signal the end: Regulation by E3 ubiquitin ligases recognizing protein termini. Molecular Cell 82 (8), pp. 1424 - 1438 (2022)