Publications of R. Huber

Ramachandran, R.; Hartmann, C.; Song, H. K.; Huber, R.; Bochtler, M.: Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY). Proceedings of the National Academy of Sciences of the United States of America 99 (11), pp. 7396 - 7401 (2002)

Seifert, M. H. J.; Breitenlechner, C. B.; Bossemeyer, D.; Huber, R.; Holak, T. A.; Engh, R. A.: Phosphorylation and flexibility of cyclic-AMP-dependent protein kinase (PKA) using P-31 NMR Spectroscopy. Biochemistry 41 (19), pp. 5968 - 5977 (2002)

Than, M. E.; Henrich, S.; Huber, R.; Ries, A.; Mann, K.; Kühn, K.; Timpl, R.; Bourenkov, G. P.; Bartunik, H. D.; Bode, W.: The 1.9-angstrom crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link. Proceedings of the National Academy of Sciences of the United States of America 99 (10), pp. 6607 - 6612 (2002)

Groll, M.; Nazif, T.; Huber, R.; Bogyo, M.: Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome. Chemistry & Biology 9 (5), pp. 655 - 662 (2002)

Garrido-Franco, M.; Ehlert, S.; Messerschmidt, A.; Marinkovic, S.; Huber, R.; Laber, B.; Bourenkov, G. P.; Clausen, T.: Structure and function of threonine synthase from yeast. Journal of Biological Chemistry 277 (14), pp. 12396 - 12405 (2002)

Krojer, T.; Garrido-Franco, M.; Huber, R.; Ehrmann, M.; Clausen, T.: Crystal structure of DegP (HtrA) reveals a new protease- chaperone machine. Nature 416 (6879), pp. 455 - 459 (2002)

Friedrich, R.; Steinmetzer, T.; Huber, R.; Stürzebecher, J.; Bode, W.: The methyl group of N-alpha(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage. Journal of Molecular Biology 316 (4), pp. 869 - 874 (2002)

Richardson, J. L.; Fuentes-Prior, P.; Sadler, J. E.; Huber, R.; Bode, W.: Characterization of the residues involved in the human alpha- thrombin-haemadin complex: An exosite II-binding inhibitor. Biochemistry 41 (8), pp. 2535 - 2542 (2002)

Schramek, N.; Bracher, A.; Fischer, M.; Auerbach, G.; Nar, H.; Huber, R.; Bacher, A.: Reaction mechanism of GTP cyclohydrolase I: Single turnover experiments using a kinetically competent reaction intermediate. Journal of Molecular Biology 316 (3), pp. 829 - 837 (2002)

Grazulis, S.; Deibert, M.; Rimseliene, R.; Skirgaila, R.; Sasnauskas, G.; Lagunavicius, A.; Repin, V.; Urbanke, C.; Huber, R.; Siksnys, V.: Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence. Nucleic Acids Research 30 (4), pp. 876 - 885 (2002)

Friedrich, R.; Fuentes-Prior, P.; Ong, E.; Coombs, G.; Hunter, M.; Oehler, R.; Pierson, D.; Gonzalez, R.; Huber, R.; Bode, W. et al.; Madison, E. L.: Catalytic domain structures of MT-SP1/matriptase, a matrix- degrading transmembrane serine proteinase. Journal of Biological Chemistry 277 (3), pp. 2160 - 2168 (2002)

Budisa, N.; Rubini, M.; Bae, J. H.; Weyher, E.; Wenger, W.; Golbik, R.; Huber, R.; Moroder, L.: Global replacement of tryptophan with aminotryptophans generates non-invasive protein-based optical pH sensors. Angewandte Chemie-International Edition 41 (21), pp. 4066 - 4069 (2002)

Declerck, N.; Machius, M.; Joyet, P.; Wiegand, G.; Huber, R.; Gaillardin, C.: Engineering the thermostability of Bacillus licheniformis alpha-amylase. Biologia 57 (Suppl. 11), pp. 203 - 211 (2002)

Fischer, M.; Haase, I.; Feicht, R.; Richter, G.; Gerhardt, S.; Changeux, J. P.; Huber, R.; Bacher, A.: Biosynthesis of riboflavin - 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. European Journal of Biochemistry 269 (2), pp. 519 - 526 (2002)

Gerhardt, S.; Haase, I.; Steinbacher, S.; Kaiser, J. T.; Cushman, M.; Bacher, A.; Huber, R.; Fischer, M.: The structural basis of riboflavion binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase. Journal of Molecular Biology 318, pp. 1317 - 1329 (2002)

Kaiser, M.; Groll, M.; Renner, C.; Huber, R.; Moroder, L.: The core structure of TMC-95A is a promising lead for reversible proteasome inhibition. Angewandte Chemie-International Edition 41 (5), pp. 780 - 783 (2002)

Song, H. K.; Mulrooney, S. B.; Huber, R.; Hausinger, R. P.: Crystal structure of Klebsiella aerogenes UreE, a nickel- binding metallochaperone for urease activation. Journal of Biological Chemistry 276 (52), pp. 49359 - 49364 (2001)

Riedl, S. J.; Fuentes-Prior, P.; Renatus, M.; Kairies, N.; Krapp, S.; Huber, R.; Salvesen, G. S.; Bode, W.: Structural basis for the activation of human procaspase-7. Proceedings of the National Academy of Sciences of the United States of America 98 (26), pp. 14790 - 14795 (2001)

Dorowski, A.; Hofmann, A.; Steegborn, C.; Boicu, M.; Huber, R.: Crystal Structure of Paprika Ferredoxin-NADP(+)Reductase – Implications for the Electron Transfer Pathway. J. Biol. Chem. 276 (12), pp. 9253 - 9263 (2001)

Bergner, A.; Oganessyan, V.; Muta, T.; Iwanaga, S.; Typke, D.; Huber, R.; Bode, W.: Crystal structure of coagulogen, the clotting protein from horseshoe crab - a structural homologue of nerve growth factor. EMBO Journal 15 (24), pp. 6789 - 6797 (1996)