Publications of Wolfram Bode

Journal Article (70)

1.
Journal Article
Debela, M.; Magdolen, V.; Skala, W.; Elsasser, B.; Schneider, E. L.; Craik, C. S.; Biniossek, M. L.; Schilling, O.; Bode, W.; Brandstetter, H. et al.; Goettig, P.: Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin. Scientific Reports 8, 10705 (2018)
2.
Journal Article
Arolas, J. L.; Broder, C.; Jefferson, T.; Guevara, T.; Sterchi, E. E.; Bode, W.; Stocker, W.; Becker-Pauly, C.; Gomis-Ruth, F. X.: Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane. Proceedings of the National Academy of Sciences of the United States of America 109 (40), pp. 16131 - 16136 (2012)
3.
Journal Article
Tochowicz, A.; Goettig, P.; Visse, R.; Shitomi, Y.; Maskos, K.; Nagase, H.; Bode, W.; Itoh, Y.: Crystal structure of MT1-MMP hemopexin domain: identification of the dimer interface. International Journal of Experimental Pathology 91 (6), pp. A39 - A40 (2010)
4.
Journal Article
Tochowicz, A.; Maskos, K.; Huber, R.; Oltenfreiter, R.; Dive, V.; Yiotakis, A.; Zanda, M.; Pourmotabbed, T.; Bode, W.; Goettig, P.: Corrigendum to "Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side Chain to Selectivity" (Journal of Molecular Biology, vol 371, pg 989, 2007). Journal of Molecular Biology 388 (4), pp. 917 - 918 (2009)
5.
Journal Article
Wisniewska, M.; Goettig, P.; Maskos, K.; Belouski, E.; Winters, D.; Hecht, R.; Black, R.; Bode, W.: Structural determinants of the ADAM inhibition by TIMP-3: Crystal structure of the TACE-N-TIMP-3 complex. Journal of Molecular Biology 381 (5), pp. 1307 - 1319 (2008)
6.
Journal Article
Pallares, I.; Fernandez, D.; Comellas-Bigler, M.; Fernandez-Recio, J.; Ventura, S.; Aviles, F. X.; Bode, W.; Vendrell, J.: Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid). Acta Crystallographica Section D-Biological Crystallography 64, pp. 784 - 791 (2008)
7.
Journal Article
Debela, M.; Beaufort, N.; Magdolen, V.; Schechter, N. M.; Craik, C. S.; Schmitt, M.; Bode, W.; Goettig, P.: Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7. Biological Chemistry 389 (6), pp. 623 - 632 (2008)
8.
Journal Article
Friedrich, R.; Riester, D.; Göttig, P.; Thurk, M.; Schwienhorst, A.; Bode, W.: Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue. European Journal of Medicinal Chemistry 43 (6), pp. 1330 - 1335 (2008)
9.
Journal Article
Barazza, A.; Gotz, M.; Cadamuro, S. A.; Goettig, P.; Willem, M.; Steuber, H.; Kohler, T.; Jestel, A.; Reinemer, P.; Renner, C. et al.; Bode, W.; Moroder, L.: Macrocyclic statine-based inhibitors of BACE-1. ChemBioChem 8 (17), pp. 2078 - 2091 (2007)
10.
Journal Article
Debela, M.; Goettig, P.; Magdolen, V.; Huber, R.; Schechter, N. M.; Bode, W.: Structural basis of the zinc inhibition of human tissue kallikrein 5. Journal of Molecular Biology 373 (4), pp. 1017 - 1031 (2007)
11.
Journal Article
Debela, M.; Hess, P.; Magdolen, V.; Schechter, N. M.; Steiner, T.; Huber, R.; Bode, W.; Goettig, P.: Chymotryptic specificity determinants in the 1.0 angstrom structure of the zinc-inhibited human tissue kallikrein 7. Proceedings of the National Academy of Sciences of the United States of America 104 (41), pp. 16086 - 16091 (2007)
12.
Journal Article
Tochowicz, A.; Maskos, K.; Huber, R.; Oltenfreiter, R.; Dive, V.; Yiotakis, A.; Zanda, M.; Bode, W.; Goettig, P.: Crystal structures of MMP-9 complexes with five inhibitors: Contribution of the flexible arg424 side-chain to selectivity. Journal of Molecular Biology 371 (4), pp. 989 - 1006 (2007)
13.
Journal Article
Keil, C.; Maskos, K.; Than, M.; Hoopes, J.T.; Huber, R.; Tan, F.; Deddish, P.A.; Erdös, E.G.; Skidgel, R.A.; Bode, W.: Crystal Structure of the Human Carboxypeptidase N (Kininase I) Catalytic Domain. Journal of Molecular Biology 366, pp. 504 - 516 (2007)
14.
Journal Article
Debela, M.; Magdolen, V.; Grimminger, V.; Sommerhoff, C.; Messerschmidt, A.; Huber, R.; Friedrich, R.; Bode, W.; Goettig, P.: Crystal structures of human tissue kallikrein 4: Activity modulation by a specific zinc binding site. Journal of Molecular Biology 362 (5), pp. 1094 - 1107 (2006)
15.
Journal Article
Debela, M.; Magdolen, V.; Schechter, N.; Valachova, M.; Lottspeich, F.; Craik, C. S.; Choe, Y.; Bode, W.; Goettig, P.: Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences. Journal of Biological Chemistry 281 (35), pp. 25678 - 25688 (2006)
16.
Journal Article
Steiner, H.; Than, M.; Bode, W.; Haass, C.: Pore-forming scissors? A first structural glimpse of gamma-secretase. Trends in Biochemical Sciences 31 (9), pp. 491 - 493 (2006)
17.
Journal Article
Steinmetzer, T.; Schweinitz, A.; Sturzebecher, A.; Donnecke, D.; Uhland, K.; Schuster, O.; Steinmetzer, P.; Muller, F.; Friedrich, R.; Than, M. E. et al.; Bode, W.; Sturzbecher, J.: Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. Journal of Medicinal Chemistry 49 (14), pp. 4116 - 4126 (2006)
18.
Journal Article
Bode, W.: The structure of thrombin: A janus-headed proteinase. Seminars in Thrombosis and Hemostasis 32 (Suppl. Suppl. 1), pp. 16 - 31 (2006)
19.
Journal Article
Rohr, K. B.; Selwood, T.; Marquardt, U.; Huber, R.; Schechter, N. M.; Bode, W.; Than, M. E.: X-ray structures of free and leupeptin-complexed human alpha I-tryptase mutants: Indication for an alpha ->beta-tryptase transition. Journal of Molecular Biology 357 (1), pp. 195 - 209 (2006)
20.
Journal Article
Bode, W.: Structure and interaction modes of thrombin. Blood Cells Molecules and Diseases 36 (2), pp. 122 - 130 (2006)
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