Publications of U. Rothweiler

Orth, M.; Mayer, B.; Rehm, K.; Rothweiler, U.; Heidmann, D.; Holak, T. A.; Stemmann, O.: Shugoshin is a Mad1/Cdc20-like interactor of Mad2. EMBO Journal 30 (14), pp. 2868 - 2880 (2011)

Rothweiler, U.; Czarna, A.; Weber, L.; Popowicz, G. M.; Brongel, K.; Kowalska, K.; Orth, M.; Stemmann, O.; Holak, T. A.: NMR screening for lead compounds using tryptophan-mutated proteins. Journal of Medicinal Chemistry 51 (16), pp. 5035 - 5042 (2008)

Rothweiler, U.; Czarna, A.; Krajewski, M.; Ciombor, J.; Kalinski, C.; Khazak, V.; Ross, G.; Skobeleva, N.; Weber, L.; Holak, T. A.: Isoquinolin-1-one inhibitors of the MDM2-p53 interaction. ChemMedChem 3 (7), pp. 1118 - 1128 (2008)

Popowicz, G. M.; Czarna, A.; Rothweiler, U.; Szwagierczak, A.; Krajewski, M.; Weber, L.; Holak, T. A.: Molecular basis for the inhibition of p53 by Mdmx. Cell Cycle 6 (19), pp. 2386 - 2392 (2007)

Krajewski, M.; Rothweiler, U.; D'Silva, L.; Majumdar, S.; Klein, C.; Holak, T. A.: An NMR-Based antagonist induced dissociation assay for targeting the ligand-protein and protein-protein interactions in competition binding experiments. Journal of Medicinal Chemistry 50 (18), pp. 4382 - 4387 (2007)

Krajewski, M.; Ozdowy, P.; D'Silva, L.; Rothweiler, U.; Holak, T. A.: NMR indicates that the small molecule RITA does not block p53-MDM2 binding in vitro. Nature Medicine 11 (11), pp. 1135 - 1136 (2005)

D'Silva, L.; Ozdowy, P.; Krajewski, M.; Rothweiler, U.; Singh, M.; Holak, T. A.: Monitoring the effects of antagonists on protein-protein interactions with NMR spectroscopy. Journal of the American Chemical Society 127 (38), pp. 13220 - 13226 (2005)

Rothweiler, U.: Untersuchung von Protein-Protein Wechselwirkungen von Zellzyklusproteinen und deren Störung mittels kleiner organischer Inhibitoren. Dissertation, Technische Universität, München (2007)