Publications of Reinhard Fässler

Huber, M.; Casares-Arias, J.; Fässler, R.; Mueller, D. J.; Strohmeyer, N.: In mitosis integrins reduce adhesion to extracellular matrix and strengthen adhesion to adjacent cells. Nature Communications 14 (1), 2143 (2023)

Guo, S. S.; Fässler, R.: KANK proteins. Current Biology 32 (19), pp. R990 - R992 (2022)

Thievessen, I.; Suhr, F.; Vergarajauregui, S.; Böttcher, R. T.; Brixius, K.; Rosenberger, G.; Dewald, O.; Fleischmann, B. K.; Ghanem, A.; Kruger, M. et al.; Engel, F. B.; Fabry, B.; Bloch, W.; Fässler, R.: The focal adhesion protein beta-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load. Current Biology 32 (14), pp. 3033 - 3047 (2022)

de Faria, J. P.; Vale-Silva, R. S.; Fässler, R.; Werner, H. B.; Relvas, J. B.: Pinch2 regulates myelination in the mouse central nervous system. Development 149 (13), dev200597 (2022)

Zuidema, A.; Atherton, P.; Kreft, M.; Hoekman, L.; Bleijerveld, O. B.; Nagaraj, N.; Chen, N.; Fässler, R.; Sonnenberg, A.: PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins. Journal of Cell Biology 221 (8), e202108027 (2022)

Zuidema, A.; Wang, W.; Kreft, M.; Bleijerveld, O. B.; Hoekman, L.; Aretz, J.; Böttcher, R. T.; Fässler, R.; Sonnenberg, A.: Molecular determinants of alpha V beta 5 localization in flat clathrin lattices - role of alpha V beta 5 in cell adhesion and proliferation. Journal of Cell Science 135 (11), jcs259465 (2022)

Böttcher, R. T.; Strohmeyer, N.; Aretz, J.; Fässler, R.: New insights into the phosphorylation of the threonine motif of the β1 integrin cytoplasmic domain. Life science alliance 5 (4), e202101301 (2022)

Fischer, A.; Wannemacher, J.; Christ, S.; Koopmans, T.; Kadri, S.; Zhao, J. K.; Gouda, M.; Ye, H. F.; Muck-Hausl, M.; Krenn, P. W. et al.; Machens, H. G.; Fässler, R.; Neumann, P. A.; Hauck, S. M.; Rinkevich, Y.: Neutrophils direct preexisting matrix to initiate repair in damaged tissues. Nature Immunology 23 (4), pp. 518 - 531 (2022)

Chen, N.-P.; Aretz, J.; Fässler, R.: CDK1-cyclin-B1-induced kindlin degradation drives focal adhesion disassembly at mitotic entry. Nature Cell Biology (2022)

Sevilla-Movilla, S.; Fuentes, P.; Rodriguez-Garcia, Y.; Arellano-Sanchez, N.; Krenn, P. W.; Isern de Val, S.; Montero-Herradon, S.; Garcia-Ceca, J.; Burdiel-Herencia, V.; Gardeta, S. R. et al.; Aguilera-Montilla, N.; Barrio-Alonso, C.; Crainiciuc, G.; Bouvard, D.; Garcia-Pardo, A.; Zapata, A. G.; Hidalgo, A.; Fässler, R.; Carrasco, Y. R.; Toribio, M. L.; Teixido, J.: ICAP-1 loss impairs CD8(+) thymocyte development and leads to reduced marginal zone B cells in mice. European Journal of Immunology (2022)

Shi, Y.; Berking, A.; Baade, T.; Legate, K. R.; Fässler, R.; Hauck, C. R.: PIP5KI gamma 90-generated phosphatidylinositol-4,5-bisphosphate promotes the uptake of Staphylococcus aureus by host cells. Molecular Microbiology 116, pp. 1249 - 1267 (2021)

Bulus, N.; Brown, K. L.; Mernaugh, G.; Böttcher, A.; Dong, X.; Sanders, C. R.; Pozzi, A.; Fässler, R.; Zent, R.: Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice. The Journal of Biological Chemistry 296, 100361 (2021)

Fischer, L.; Klingner, C.; Schlichthärle, T.; Strauss, M. T.; Böttcher, R. T.; Fässler, R.; Jungmann, R.; Grashoff, C.: Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion. Nature Communications 12 (1), 919 (2021)

Guo, S. S.; Seiwert, A.; Szeto, I. Y.Y.; Fässler, R.: Tissue distribution and subcellular localization of the family of Kidney Ankyrin Repeat Domain (KANK) proteins. Experimental Cell Research 398 (1), 112391 (2021)

Mole, M. A.; Weberling, A.; Fässler, R.; Campbell, A.; Fishel, S.; Zernicka-Goetz, M.: Integrin beta 1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition. Cell Reports 34 (10), 108834 (2021)

Orre, T.; Joly, A.; Karatas, Z.; Kastberger, B.; Cabriel, C.; Böttcher, R. T.; Leveque-Fort, S.; Sibarita, J.-B.; Fässler, R.; Wehrle-Haller, B. et al.; Rossier, O.; Giannone, G.: Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions. Nature Communications 12 (1), 3104 (2021)

Rabanal-Ruiz, Y.; Byron, A.; Wirth, A.; Madsen, R.; Sedlackova, L.; Hewitt, G.; Nelson, G.; Stingele, J.; Wills, J. C.; Zhang, T. et al.; Zeug, A.; Faessler, R.; Vanhaesebroeck, B.; Maddocks, O. D. K.; Ponimaskin, E.; Carroll, B.; Korolchuk I, V.: mTORC1 activity is supported by spatial association with focal adhesions. The Journal of Cell Biology 220 (5), e202004010 (2021)

Ruiz-Ojeda, F. J.; Wang, J.; Baecker, T.; Krueger, M.; Zamani, S.; Rosowski, S.; Gruber, T.; Onogi, Y.; Feuchtinger, A.; Schulz, T. J. et al.; Faessler, R.; Mueller, T. D.; Garcia-Caceres, C.; Meier, M.; Blueher, M.; Ussar, S.: Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis. Molecular Metabolism 45, 101147 (2021)

Brod, F.; Fässler, R.: A FAK conundrum is solved: activation and organization of focal adhesion kinase at the plasma membrane. EMBO Journal 39, e106234 (2020)

Benito-Jardon, M.; Strohmeyer, N.; Ortega-Sanchis, S.; Bharadwaj, M.; Moser, M.; Mueller, D. J.; Fässler, R.; Costell, M.: alpha v-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation. The Journal of Cell Biology 219 (12), e202004198 (2020)